Annotation Detail for CASP14
Basic Information Top
| Gene Symbol: | CASP14 ( MGC119078,MGC119079 ) |
|---|---|
| Gene Full Name: | caspase 14, apoptosis-related cysteine peptidase |
| Band: | 19p13.12 |
| Quick Links | Entrez ID:23581; OMIM: 605848; Uniprot ID:CASPE_HUMAN; ENSEMBL ID: ENSG00000105141; HGNC ID: 1502 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.466057
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 1 / 564012 | 1 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 60 / 1939121 | 30 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 3 / 17475 | 171 |  |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 1 / 136302 | 7 |  |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 61 / 3360307 | 18 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 2 / 124949 | 16 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 31 / 90257 | 343 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 3 / 29757 | 100 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 0 / 1100989 | 0 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 3 / 91610 | 32 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 61 / 210574 | 289 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 55 / 232878 | 236 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_13763_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.03 ± 1.07 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.5 ± 0.21 | |
| Basal Part of Pons | 1.24 ± 0.43 | |
| Cerebellar Cortex | 1.4 ± 0.72 | |
| Cerebellar Nuclei | 1.85 ± 0.66 | |
| Claustrum | 2.45 ± 0.95 | |
| Epithalamus | 1.47 ± 0.9 | |
| Frontal Lobe | 1.39 ± 0.63 | |
| Globus Pallidus | 2.28 ± 0.68 | |
| Hypothalamus | 1.67 ± 0.62 | |
| Insula | 1.45 ± 0.52 | |
| Limbic Lobe | 1.6 ± 0.78 | |
| Mesencephalon | 1.71 ± 0.76 | |
| Myelencephalon | 1.62 ± 0.7 | |
| Occipital Lobe | 1.69 ± 0.69 | |
| Parietal Lobe | 1.66 ± 0.88 | |
| Pontine Tegmentum | 1.65 ± 0.71 | |
| Striatum | 1.67 ± 0.54 | |
| Subthalamus | 1.67 ± 0.65 | |
| Temporal Lobe | 1.49 ± 0.73 | |
| Thalamus | 1.56 ± 0.7 | |
| White Matter | 2.07 ± 0.06 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Casp14 | CB | Cerebellum | 2.5 | |
| 2.82 | | |||
| Casp14 | CTX | Cerebral cortex | 0.49 | |
| 0.51 | | |||
| Casp14 | HIP | Hippocampal region | 0.21 | |
| 0.24 | | |||
| Casp14 | HPF | Hippocampal formation | 0.25 | |
| 0.28 | | |||
| Casp14 | HY | Hypothalamus | 0.08 | |
| 0.09 | | |||
| Casp14 | LSX | Lateral septal complex | 0.06 | |
| 0.04 | | |||
| Casp14 | MB | Midbrain | 0.82 | |
| 0.89 | | |||
| Casp14 | MY | Medulla | 2.09 | |
| 3.17 | | |||
| Casp14 | OLF | Olfactory bulb | 2.25 | |
| 2.81 | | |||
| Casp14 | P | Pons | 2.92 | |
| 4.39 | | |||
| Casp14 | PAL | Pallidum | 0.06 | |
| 0.04 | | |||
| Casp14 | RHP | Retrohippocampal region | 0.33 | |
| 0.34 | | |||
| Casp14 | sAMY | Striatum-like amygdalar nuclei | 0.08 | |
| 0.31 | | |||
| Casp14 | STR | Striatum | 0.09 | |
| 0.12 | | |||
| Casp14 | STRd | Striatum dorsal region | 0.09 | |
| 0.13 | | |||
| Casp14 | STRv | Striatum ventral region | 0.1 | |
| 0.06 | | |||
| Casp14 | TH | Thalamus | 0.1 | |
| 0.1 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| CASPE_HUMAN_183 | 14 | 183 | 196 | GSCFIQTLVDVFTK | PRIDE |
| PAp00044679 | 11 | 105 | 115 | LENLFEALNNK | Peptide Atlas |