AutismKB 2.0

Annotation Detail for PDSS1


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Basic Information Top
Gene Symbol:PDSS1 ( COQ1,DPS,MGC70953,RP13-16H11.3,SPS,TPRT,TPT,hDPS1 )
Gene Full Name: prenyl (decaprenyl) diphosphate synthase, subunit 1
Band: 10p12.1
Quick LinksEntrez ID:23590; OMIM: 607429; Uniprot ID:DPS1_HUMAN; ENSEMBL ID: ENSG00000148459; HGNC ID: 17759
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult59 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor15 / 114246131
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal43 / 336030712
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor18 / 125191143
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood2 / 12347816
bone3 / 7165541
bone marrow0 / 488010 
brain7 / 11009896
cervix1 / 4817120
connective tissue20 / 149255133
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye2 / 2110549
heart1 / 8962611
intestine20 / 23447285
kidney10 / 21177747
larynx1 / 2414541
liver2 / 2077439
lung5 / 33697414
lymph0 / 442700 
lymph node2 / 9161021
mammary gland3 / 15327119
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate1 / 1893455
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach2 / 9661920
testis4 / 33044212
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220865_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts90.3
Adipocyte5
AdrenalCortex5.35
Adrenalgland4.3
Amygdala5.5
Appendix5.15
AtrioventricularNode4.3
BDCA4+_DentriticCells6.3
Bonemarrow5.15
BronchialEpithelialCells5.3
CD105+_Endothelial15.8
CD14+_Monocytes5.6
CD19+_BCells(neg._sel.)5.35
CD33+_Myeloid38.2
CD34+29.55
CD4+_Tcells5.2
CD56+_NKCells5.95
CD71+_EarlyErythroid4.75
CD8+_Tcells4.8
CardiacMyocytes7.1
Caudatenucleus4.6
Cerebellum4.15
CerebellumPeduncles5.9
CiliaryGanglion4.2
CingulateCortex5.3
Colorectaladenocarcinoma5.7
DorsalRootGanglion4
FetalThyroid5
Fetalbrain5.05
Fetalliver4.5
Fetallung4.15
GlobusPallidus3.75
Heart6.7
Hypothalamus5.6
Kidney4.3
Leukemia_chronicMyelogenousK-5625
Leukemia_promyelocytic-HL-6012.65
Leukemialymphoblastic(MOLT-4)59.3
Liver6.7
Lung5.65
Lymphnode4.45
Lymphoma_burkitts(Daudi)12.55
Lymphoma_burkitts(Raji)7.35
MedullaOblongata4.75
OccipitalLobe4.55
OlfactoryBulb3.9
Ovary3.5
Pancreas4.15
PancreaticIslet5.4
ParietalLobe5.5
Pituitary5.95
Placenta5.2
Pons4.95
PrefrontalCortex6.35
Prostate5.9
Salivarygland4.15
SkeletalMuscle6.7
Skin4.05
SmoothMuscle5.75
Spinalcord5.45
SubthalamicNucleus4.65
SuperiorCervicalGanglion8.1
TemporalLobe4.75
Testis4.4
TestisGermCell4.55
TestisIntersitial4.35
TestisLeydigCell5.1
TestisSeminiferousTubule4.5
Thalamus5.15
Thymus7.1
Thyroid6.4
Tongue5.25
Tonsil5.05
Trachea4.25
TrigeminalGanglion5.25
Uterus4.25
UterusCorpus4.7
WholeBlood5.5
Wholebrain4.3
colon28.3
pineal_day6.14
pineal_night6.24
retina6.225
small_intestine23.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8416_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.45 ± 0.24
Basal Forebrain6.41 ± 0.22
Basal Part of Pons5.91 ± 0.28
Cerebellar Cortex6.46 ± 0.27
Cerebellar Nuclei6.09 ± 0.3
Claustrum6.37 ± 0.51
Epithalamus5.94 ± 0.25
Frontal Lobe6.05 ± 0.3
Globus Pallidus6.09 ± 0.32
Hypothalamus5.98 ± 0.26
Insula5.98 ± 0.31
Limbic Lobe6.3 ± 0.34
Mesencephalon6.22 ± 0.31
Myelencephalon6.19 ± 0.35
Occipital Lobe6.53 ± 0.36
Parietal Lobe6.23 ± 0.35
Pontine Tegmentum6.16 ± 0.37
Striatum6.37 ± 0.39
Subthalamus6.31 ± 0.37
Temporal Lobe6.1 ± 0.35
Thalamus6.05 ± 0.34
White Matter6.33 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pdss1CBCerebellum40.79
57.33
Pdss1CTXCerebral cortex92.97
83.64
Pdss1HIPHippocampal region49.33
74.16
Pdss1HPFHippocampal formation57.79
68.51
Pdss1HYHypothalamus25.19
22.2
Pdss1LSXLateral septal complex31.95
24.16
Pdss1MBMidbrain41.4
39.37
Pdss1MYMedulla52.54
57.26
Pdss1OLFOlfactory bulb68.25
65.07
Pdss1PPons35.92
37.8
Pdss1PALPallidum38.04
40.69
Pdss1RHPRetrohippocampal region71.46
62.22
Pdss1sAMYStriatum-like amygdalar nuclei60.81
52.45
Pdss1STRStriatum31.84
26.38
Pdss1STRdStriatum dorsal region26.26
21.99
Pdss1STRvStriatum ventral region37.48
29.19
Pdss1THThalamus62.55
55.04
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DPS1_HUMAN_102 10 102 111 DLKGLYEDIR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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