AutismKB 2.0

Annotation Detail for OPN3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:OPN3 ( ECPN )
Gene Full Name: opsin 3
Band: 1q43
Quick LinksEntrez ID:23596; OMIM: 606695; Uniprot ID:OPN3_HUMAN; ENSEMBL ID: ENSG00000054277; HGNC ID: 14007
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst3 / 6231948
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult75 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor5 / 26384518
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal98 / 336030729
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone1 / 7165513
bone marrow0 / 488010 
brain14 / 110098912
cervix7 / 48171145
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye7 / 21105433
heart1 / 8962611
intestine2 / 2344728
kidney6 / 21177728
larynx1 / 2414541
liver4 / 20774319
lung13 / 33697438
lymph0 / 442700 
lymph node1 / 9161010
mammary gland5 / 15327132
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta33 / 280825117
prostate2 / 18934510
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach1 / 9661910
testis9 / 33044227
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219032_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.75
Adipocyte9.3
AdrenalCortex7.4
Adrenalgland6.2
Amygdala19.4
Appendix6.25
AtrioventricularNode5.5
BDCA4+_DentriticCells806.15
Bonemarrow11.45
BronchialEpithelialCells35.95
CD105+_Endothelial9.1
CD14+_Monocytes205.1
CD19+_BCells(neg._sel.)403.15
CD33+_Myeloid161.1
CD34+167.05
CD4+_Tcells8.05
CD56+_NKCells18.05
CD71+_EarlyErythroid5.85
CD8+_Tcells6.8
CardiacMyocytes8.95
Caudatenucleus6.4
Cerebellum5.75
CerebellumPeduncles8.15
CiliaryGanglion4.05
CingulateCortex64.85
Colorectaladenocarcinoma8.3
DorsalRootGanglion5.65
FetalThyroid6.95
Fetalbrain6.5
Fetalliver24.7
Fetallung19.9
GlobusPallidus10.3
Heart9.05
Hypothalamus12.6
Kidney10.95
Leukemia_chronicMyelogenousK-56213.75
Leukemia_promyelocytic-HL-604.45
Leukemialymphoblastic(MOLT-4)5.4
Liver9.5
Lung64.05
Lymphnode20.05
Lymphoma_burkitts(Daudi)9.3
Lymphoma_burkitts(Raji)8.2
MedullaOblongata22.15
OccipitalLobe35.75
OlfactoryBulb7.25
Ovary4.7
Pancreas4.05
PancreaticIslet7.7
ParietalLobe40.5
Pituitary7.75
Placenta324.5
Pons8.35
PrefrontalCortex82.8
Prostate8.5
Salivarygland7.85
SkeletalMuscle8.45
Skin5.5
SmoothMuscle6.8
Spinalcord7.35
SubthalamicNucleus23.6
SuperiorCervicalGanglion8.05
TemporalLobe23.6
Testis6.15
TestisGermCell6.3
TestisIntersitial6.1
TestisLeydigCell7.1
TestisSeminiferousTubule6.1
Thalamus92.5
Thymus7.8
Thyroid18.85
Tongue5
Tonsil8.55
Trachea5.8
TrigeminalGanglion7.6
Uterus5.5
UterusCorpus6.05
WholeBlood25.65
Wholebrain128.8
colon7.85
pineal_day7.6
pineal_night8.04
retina9.175
small_intestine6.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6195_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.47 ± 1.16
Basal Forebrain5.05 ± 0.55
Basal Part of Pons6.71 ± 0.38
Cerebellar Cortex5.06 ± 0.68
Cerebellar Nuclei5.76 ± 0.64
Claustrum5.74 ± 0.69
Epithalamus4.97 ± 1.01
Frontal Lobe6.17 ± 0.75
Globus Pallidus4.1 ± 1.4
Hypothalamus5.71 ± 0.44
Insula5.78 ± 0.37
Limbic Lobe5.38 ± 0.87
Mesencephalon5.73 ± 0.83
Myelencephalon5.85 ± 0.93
Occipital Lobe6.45 ± 0.6
Parietal Lobe6.44 ± 0.89
Pontine Tegmentum5.68 ± 0.89
Striatum5.03 ± 1.27
Subthalamus5.52 ± 0.83
Temporal Lobe5.95 ± 0.88
Thalamus7.12 ± 0.75
White Matter4.67 ± 1.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Opn3CBCerebellum16.19
46.86
Opn3CTXCerebral cortex1.19
1.08
Opn3HIPHippocampal region0.13
0.24
Opn3HPFHippocampal formation0.21
0.35
Opn3HYHypothalamus1.06
1.11
Opn3LSXLateral septal complex0.2
0.17
Opn3MBMidbrain0.37
0.7
Opn3MYMedulla1.03
1.71
Opn3OLFOlfactory bulb1.16
1.35
Opn3PPons0.49
0.82
Opn3PALPallidum0.69
1
Opn3RHPRetrohippocampal region0.32
0.46
Opn3sAMYStriatum-like amygdalar nuclei0.21
0.21
Opn3STRStriatum1.83
1.46
Opn3STRdStriatum dorsal region2.37
1.91
Opn3STRvStriatum ventral region1.81
1.36
Opn3THThalamus10.52
9.85
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved