AutismKB 2.0

Annotation Detail for ZMYND8


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Basic Information Top
Gene Symbol:ZMYND8 ( MGC31836,PRKCBP1,PRO2893,RACK7 )
Gene Full Name: zinc finger, MYND-type containing 8
Band: 20q13.12
Quick LinksEntrez ID:23613; OMIM: NA; Uniprot ID:PKCB1_HUMAN; ENSEMBL ID: ENSG00000101040; HGNC ID: 9397
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst13 / 62319208
fetus130 / 564012230
neonate2 / 3109764
infant0 / 236200 
juvenile8 / 55556143
adult223 / 1939121115
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult4 / 19391212
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult3 / 19391211
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor12 / 94178127
cervical tumor2 / 3436658
chondrosarcoma16 / 82823193
colorectal tumor25 / 114246218
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor33 / 263845125
glioma15 / 106883140
head and neck tumor14 / 136302102
kidney tumor0 / 689590 
leukemia18 / 95842187
liver tumor15 / 96359155
lung tumor7 / 10312767
lymphoma1 / 7175513
non-neoplasia11 / 97250113
normal410 / 3360307122
ovarian tumor7 / 7668291
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer5 / 10268048
retinoblastoma4 / 4635686
skin tumor8 / 12494964
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor7 / 9025777
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal11 / 33603073
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal3 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites1 / 4001524
bladder3 / 29757100
blood9 / 12347872
bone5 / 7165569
bone marrow9 / 48801184
brain136 / 1100989123
cervix2 / 4817141
connective tissue18 / 149255120
ear1 / 1621261
embryonic tissue31 / 215722143
esophagus1 / 2020949
eye24 / 211054113
heart10 / 89626111
intestine47 / 234472200
kidney7 / 21177733
larynx2 / 2414582
liver24 / 207743115
lung43 / 336974127
lymph1 / 4427022
lymph node22 / 91610240
mammary gland14 / 15327191
mouth9 / 67052134
muscle5 / 10771546
nerve2 / 15768126
ovary8 / 10205178
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta27 / 28082596
prostate13 / 18934568
salivary gland1 / 2015549
skin28 / 210574132
spleen5 / 5395292
stomach5 / 9661951
testis47 / 330442142
thymus4 / 8113149
thyroid3 / 4747363
tonsil0 / 169990 
trachea10 / 52413190
umbilical cord0 / 136800 
uterus23 / 23287898
vascular4 / 5178077
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine2 / 2344728
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney3 / 21177714
larynx0 / 241450 
liver1 / 2077434
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209049_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts363.7
Adipocyte47.15
AdrenalCortex97.8
Adrenalgland57.8
Amygdala163.45
Appendix33.9
AtrioventricularNode30.7
BDCA4+_DentriticCells135.8
Bonemarrow43.45
BronchialEpithelialCells88.75
CD105+_Endothelial453.2
CD14+_Monocytes36.05
CD19+_BCells(neg._sel.)296.5
CD33+_Myeloid245.55
CD34+730.65
CD4+_Tcells186.6
CD56+_NKCells333.7
CD71+_EarlyErythroid611.85
CD8+_Tcells310.45
CardiacMyocytes57.35
Caudatenucleus40.8
Cerebellum27.15
CerebellumPeduncles47.95
CiliaryGanglion24.4
CingulateCortex50.25
Colorectaladenocarcinoma198.3
DorsalRootGanglion26.5
FetalThyroid36.55
Fetalbrain268.55
Fetalliver85.4
Fetallung54.85
GlobusPallidus33.05
Heart41.25
Hypothalamus120.8
Kidney23.3
Leukemia_chronicMyelogenousK-562100.45
Leukemia_promyelocytic-HL-6029.35
Leukemialymphoblastic(MOLT-4)23.35
Liver36.65
Lung41.95
Lymphnode45.7
Lymphoma_burkitts(Daudi)56.25
Lymphoma_burkitts(Raji)157
MedullaOblongata67.2
OccipitalLobe61.1
OlfactoryBulb30.75
Ovary21.5
Pancreas101.7
PancreaticIslet40.05
ParietalLobe53.5
Pituitary113.75
Placenta97.55
Pons39.6
PrefrontalCortex385.95
Prostate46.75
Salivarygland27.9
SkeletalMuscle38.4
Skin25.6
SmoothMuscle35.1
Spinalcord39.15
SubthalamicNucleus72.15
SuperiorCervicalGanglion43.4
TemporalLobe41.7
Testis36.1
TestisGermCell58.55
TestisIntersitial28.7
TestisLeydigCell33.95
TestisSeminiferousTubule41.15
Thalamus48.2
Thymus31.35
Thyroid63.5
Tongue33
Tonsil38.65
Trachea29.05
TrigeminalGanglion30.3
Uterus28.35
UterusCorpus37.05
WholeBlood99.45
Wholebrain57.6
colon34.05
pineal_day449.24
pineal_night288.78
retina46.85
small_intestine39.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_688_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.25 ± 0.46
Basal Forebrain6.24 ± 0.23
Basal Part of Pons6.16 ± 0.34
Cerebellar Cortex5.93 ± 0.37
Cerebellar Nuclei5.91 ± 0.59
Claustrum6.34 ± 0.4
Epithalamus5.85 ± 0.48
Frontal Lobe6.16 ± 0.45
Globus Pallidus6.29 ± 0.27
Hypothalamus6.08 ± 0.43
Insula6.05 ± 0.48
Limbic Lobe6.29 ± 0.49
Mesencephalon5.97 ± 0.41
Myelencephalon6.12 ± 0.41
Occipital Lobe6.26 ± 0.39
Parietal Lobe6.31 ± 0.36
Pontine Tegmentum6.26 ± 0.45
Striatum6.36 ± 0.38
Subthalamus5.98 ± 0.56
Temporal Lobe6.3 ± 0.38
Thalamus6.14 ± 0.35
White Matter6.75 ± 1.03
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Prkcbp1CBCerebellum45.43
59.73
Prkcbp1CTXCerebral cortex100
100
Prkcbp1HIPHippocampal region73.89
100
Prkcbp1HPFHippocampal formation83.07
100
Prkcbp1HYHypothalamus97.25
87.01
Prkcbp1LSXLateral septal complex90.7
76.94
Prkcbp1MBMidbrain74.91
73.61
Prkcbp1MYMedulla76.57
94.15
Prkcbp1OLFOlfactory bulb100
100
Prkcbp1PPons70.15
82.56
Prkcbp1PALPallidum84.98
88.16
Prkcbp1RHPRetrohippocampal region97.66
100
Prkcbp1sAMYStriatum-like amygdalar nuclei100
89.31
Prkcbp1STRStriatum88.88
73.73
Prkcbp1STRdStriatum dorsal region82.14
66.65
Prkcbp1STRvStriatum ventral region100
96.03
Prkcbp1THThalamus98.31
94.81
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00030583 13 944 956 LQWLHQQELSEMK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018