AutismKB 2.0

Annotation Detail for TSSK2


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Basic Information Top
Gene Symbol:TSSK2 ( DGS-G,FLJ38613,SPOGA2,STK22B )
Gene Full Name: testis-specific serine kinase 2
Band: 22q11.21
Quick LinksEntrez ID:23617; OMIM: 610710; Uniprot ID:TSSK2_HUMAN; ENSEMBL ID: ENSG00000206203; HGNC ID: 11401
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal17 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis15 / 33044245
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214371_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.7
Adipocyte5.7
AdrenalCortex7.2
Adrenalgland5.1
Amygdala5.85
Appendix6.5
AtrioventricularNode4.9
BDCA4+_DentriticCells5.8
Bonemarrow6.05
BronchialEpithelialCells5.85
CD105+_Endothelial5.8
CD14+_Monocytes6.15
CD19+_BCells(neg._sel.)5.9
CD33+_Myeloid7.1
CD34+7
CD4+_Tcells6
CD56+_NKCells6.65
CD71+_EarlyErythroid5.35
CD8+_Tcells5.3
CardiacMyocytes7.35
Caudatenucleus5.15
Cerebellum4.7
CerebellumPeduncles6.8
CiliaryGanglion4.6
CingulateCortex6.45
Colorectaladenocarcinoma5.9
DorsalRootGanglion4.85
FetalThyroid6.6
Fetalbrain5.6
Fetalliver5.1
Fetallung4.6
GlobusPallidus4.2
Heart11.9
Hypothalamus6.4
Kidney5.4
Leukemia_chronicMyelogenousK-5625.1
Leukemia_promyelocytic-HL-605.15
Leukemialymphoblastic(MOLT-4)4.6
Liver8.25
Lung6.5
Lymphnode4.8
Lymphoma_burkitts(Daudi)7.65
Lymphoma_burkitts(Raji)8.6
MedullaOblongata5.2
OccipitalLobe5.15
OlfactoryBulb4.5
Ovary4.35
Pancreas4.8
PancreaticIslet6.2
ParietalLobe6.6
Pituitary6.85
Placenta5.9
Pons5.6
PrefrontalCortex7.2
Prostate6.6
Salivarygland4.85
SkeletalMuscle8.7
Skin4.95
SmoothMuscle6.6
Spinalcord6.1
SubthalamicNucleus5.2
SuperiorCervicalGanglion8
TemporalLobe5.45
Testis333.9
TestisGermCell266.1
TestisIntersitial227.45
TestisLeydigCell115.3
TestisSeminiferousTubule113.35
Thalamus5.95
Thymus4.5
Thyroid7.05
Tongue6.05
Tonsil5.7
Trachea4.8
TrigeminalGanglion6.65
Uterus4.65
UterusCorpus5.5
WholeBlood6.25
Wholebrain4.6
colon5.95
pineal_day7
pineal_night6.86
retina7
small_intestine5.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8106_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.16 ± 0.99
Basal Forebrain1.85 ± 0.42
Basal Part of Pons1.5 ± 0.63
Cerebellar Cortex1.61 ± 0.7
Cerebellar Nuclei1.99 ± 0.69
Claustrum2.54 ± 0.85
Epithalamus1.51 ± 0.82
Frontal Lobe1.58 ± 0.62
Globus Pallidus2.37 ± 0.4
Hypothalamus1.83 ± 0.82
Insula1.77 ± 1.1
Limbic Lobe1.77 ± 0.69
Mesencephalon1.9 ± 0.69
Myelencephalon1.78 ± 0.7
Occipital Lobe1.84 ± 0.66
Parietal Lobe1.68 ± 0.61
Pontine Tegmentum1.79 ± 0.69
Striatum1.86 ± 0.5
Subthalamus1.88 ± 0.7
Temporal Lobe1.64 ± 0.73
Thalamus1.69 ± 0.57
White Matter2.39 ± 0.78
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018