AutismKB 2.0

Annotation Detail for FAM89B


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Basic Information Top
Gene Symbol:FAM89B ( MTVR1 )
Gene Full Name: family with sequence similarity 89, member B
Band: 11q13.1
Quick LinksEntrez ID:23625; OMIM: NA; Uniprot ID:FA89B_HUMAN; ENSEMBL ID: ENSG00000176973; HGNC ID: 16708
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst1 / 6231916
fetus39 / 56401269
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult88 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor6 / 26384522
glioma1 / 1068839
head and neck tumor6 / 13630244
kidney tumor2 / 6895929
leukemia6 / 9584262
liver tumor0 / 963590 
lung tumor9 / 10312787
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal123 / 336030736
ovarian tumor6 / 7668278
pancreatic tumor33 / 104616315
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood3 / 12347824
bone5 / 7165569
bone marrow1 / 4880120
brain23 / 110098920
cervix2 / 4817141
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye7 / 21105433
heart6 / 8962666
intestine14 / 23447259
kidney8 / 21177737
larynx0 / 241450 
liver0 / 2077430 
lung27 / 33697480
lymph0 / 442700 
lymph node1 / 9161010
mammary gland4 / 15327126
mouth0 / 670520 
muscle5 / 10771546
nerve1 / 1576863
ovary6 / 10205158
pancreas35 / 214812162
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta7 / 28082524
prostate15 / 18934579
salivary gland6 / 20155297
skin9 / 21057442
spleen1 / 5395218
stomach4 / 9661941
testis3 / 3304429
thymus2 / 8113124
thyroid0 / 474730 
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212484_at
Cell line Expression level Expression bar
721_B_lymphoblasts35.5
Adipocyte35.9
AdrenalCortex31.1
Adrenalgland25.5
Amygdala32.85
Appendix17.5
AtrioventricularNode22.75
BDCA4+_DentriticCells62.8
Bonemarrow30.5
BronchialEpithelialCells32.5
CD105+_Endothelial48.4
CD14+_Monocytes165.15
CD19+_BCells(neg._sel.)55.15
CD33+_Myeloid79.6
CD34+42
CD4+_Tcells49.35
CD56+_NKCells134.2
CD71+_EarlyErythroid145.6
CD8+_Tcells55.3
CardiacMyocytes49.2
Caudatenucleus27.45
Cerebellum25.5
CerebellumPeduncles41.4
CiliaryGanglion21
CingulateCortex31.1
Colorectaladenocarcinoma30.45
DorsalRootGanglion22.9
FetalThyroid33.15
Fetalbrain43.15
Fetalliver25.5
Fetallung31.3
GlobusPallidus22.75
Heart77.1
Hypothalamus31.4
Kidney24.2
Leukemia_chronicMyelogenousK-56227.4
Leukemia_promyelocytic-HL-6026.4
Leukemialymphoblastic(MOLT-4)34
Liver55.95
Lung69.25
Lymphnode26.75
Lymphoma_burkitts(Daudi)38.15
Lymphoma_burkitts(Raji)43.2
MedullaOblongata26.9
OccipitalLobe26.55
OlfactoryBulb23.7
Ovary20.15
Pancreas25.95
PancreaticIslet32.65
ParietalLobe31.25
Pituitary34.5
Placenta30.5
Pons27.85
PrefrontalCortex46.75
Prostate47.55
Salivarygland22.95
SkeletalMuscle35.3
Skin22.9
SmoothMuscle34.55
Spinalcord32
SubthalamicNucleus27.45
SuperiorCervicalGanglion13.4
TemporalLobe31.4
Testis25.5
TestisGermCell23.05
TestisIntersitial24.25
TestisLeydigCell29.15
TestisSeminiferousTubule25.3
Thalamus30.65
Thymus31.5
Thyroid82.15
Tongue31.4
Tonsil34.05
Trachea24.9
TrigeminalGanglion29.25
Uterus39.1
UterusCorpus27.05
WholeBlood176
Wholebrain39.05
colon22.6
pineal_day29.44
pineal_night31.64
retina36.15
small_intestine27.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P124962
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.44 ± 0.34
Basal Forebrain10.24 ± 0.12
Basal Part of Pons10.58 ± 0.17
Cerebellar Cortex10.38 ± 0.17
Cerebellar Nuclei10.01 ± 0.33
Claustrum10.33 ± 0.17
Epithalamus9.9 ± 0.24
Frontal Lobe10.37 ± 0.3
Globus Pallidus9.49 ± 0.29
Hypothalamus10 ± 0.2
Insula10.35 ± 0.27
Limbic Lobe10.42 ± 0.33
Mesencephalon10.15 ± 0.27
Myelencephalon10.29 ± 0.31
Occipital Lobe10.22 ± 0.24
Parietal Lobe10.44 ± 0.29
Pontine Tegmentum10.2 ± 0.26
Striatum10.16 ± 0.32
Subthalamus10.12 ± 0.22
Temporal Lobe10.42 ± 0.27
Thalamus10.18 ± 0.24
White Matter9.41 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mtvr2CBCerebellum42.54
29.38
Mtvr2CTXCerebral cortex32.59
21.44
Mtvr2HIPHippocampal region29.13
17.57
Mtvr2HPFHippocampal formation29.69
20.51
Mtvr2HYHypothalamus37.37
24.24
Mtvr2LSXLateral septal complex10.28
6.59
Mtvr2MBMidbrain27.28
19.06
Mtvr2MYMedulla44.87
34.86
Mtvr2OLFOlfactory bulb62.76
39.34
Mtvr2PPons43.67
36.21
Mtvr2PALPallidum16.02
10.51
Mtvr2RHPRetrohippocampal region31.04
24.85
Mtvr2sAMYStriatum-like amygdalar nuclei33.3
21.81
Mtvr2STRStriatum16.33
10.09
Mtvr2STRdStriatum dorsal region6.55
4.13
Mtvr2STRvStriatum ventral region46.41
25.58
Mtvr2THThalamus23.4
14.63
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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