AutismKB 2.0

Annotation Detail for SSBP2


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Basic Information Top
Gene Symbol:SSBP2 ( DKFZp686F03273,HSPC116,SOSS-B2 )
Gene Full Name: single-stranded DNA binding protein 2
Band: 5q14.1
Quick LinksEntrez ID:23635; OMIM: 607389; Uniprot ID:SSBP2_HUMAN; ENSEMBL ID: ENSG00000145687; HGNC ID: 15831
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus80 / 564012141
neonate0 / 310970 
infant0 / 236200 
juvenile11 / 55556197
adult77 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor12 / 26384545
glioma2 / 10688318
head and neck tumor6 / 13630244
kidney tumor2 / 6895929
leukemia18 / 95842187
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma8 / 71755111
non-neoplasia6 / 9725061
normal229 / 336030768
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood15 / 123478121
bone4 / 7165555
bone marrow7 / 48801143
brain79 / 110098971
cervix3 / 4817162
connective tissue8 / 14925553
ear1 / 1621261
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye14 / 21105466
heart11 / 89626122
intestine1 / 2344724
kidney5 / 21177723
larynx1 / 2414541
liver2 / 2077439
lung18 / 33697453
lymph3 / 4427067
lymph node12 / 91610130
mammary gland0 / 1532710 
mouth0 / 670520 
muscle5 / 10771546
nerve2 / 15768126
ovary3 / 10205129
pancreas12 / 21481255
parathyroid3 / 20539146
pharynx7 / 41328169
pituitary gland3 / 16585180
placenta14 / 28082549
prostate2 / 18934510
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach3 / 9661931
testis8 / 33044224
thymus4 / 8113149
thyroid2 / 4747342
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus10 / 23287842
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203787_at
Cell line Expression level Expression bar
721_B_lymphoblasts28.3
Adipocyte30.35
AdrenalCortex23.25
Adrenalgland17.05
Amygdala35.85
Appendix19.65
AtrioventricularNode19.65
BDCA4+_DentriticCells19.35
Bonemarrow20.7
BronchialEpithelialCells16.85
CD105+_Endothelial50.65
CD14+_Monocytes22.5
CD19+_BCells(neg._sel.)93.95
CD33+_Myeloid33.25
CD34+144.6
CD4+_Tcells23.55
CD56+_NKCells27.2
CD71+_EarlyErythroid20.45
CD8+_Tcells13.45
CardiacMyocytes27.45
Caudatenucleus17.55
Cerebellum30.8
CerebellumPeduncles30.2
CiliaryGanglion16.1
CingulateCortex29.35
Colorectaladenocarcinoma14.7
DorsalRootGanglion26.55
FetalThyroid19.35
Fetalbrain163.35
Fetalliver16.15
Fetallung22.35
GlobusPallidus17.8
Heart32.6
Hypothalamus42.6
Kidney17.4
Leukemia_chronicMyelogenousK-56213.75
Leukemia_promyelocytic-HL-6055.8
Leukemialymphoblastic(MOLT-4)124.25
Liver27.8
Lung26.15
Lymphnode16.3
Lymphoma_burkitts(Daudi)73.4
Lymphoma_burkitts(Raji)32.3
MedullaOblongata18.5
OccipitalLobe19.2
OlfactoryBulb36.2
Ovary13.25
Pancreas15.45
PancreaticIslet21.2
ParietalLobe24.6
Pituitary34.75
Placenta18.6
Pons19.35
PrefrontalCortex44.15
Prostate21.7
Salivarygland17.3
SkeletalMuscle27.05
Skin22.8
SmoothMuscle19.5
Spinalcord36.65
SubthalamicNucleus21.4
SuperiorCervicalGanglion36
TemporalLobe20.15
Testis15.1
TestisGermCell14.75
TestisIntersitial15.3
TestisLeydigCell17.8
TestisSeminiferousTubule15.5
Thalamus25.95
Thymus151.85
Thyroid38.9
Tongue20.05
Tonsil30.2
Trachea29.6
TrigeminalGanglion28.6
Uterus37.5
UterusCorpus28.05
WholeBlood26.85
Wholebrain39.5
colon19.4
pineal_day33.46
pineal_night26.72
retina43.5
small_intestine18.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9331_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.98 ± 0.31
Basal Forebrain9.07 ± 0.21
Basal Part of Pons8.33 ± 0.16
Cerebellar Cortex8.9 ± 0.29
Cerebellar Nuclei8.68 ± 0.15
Claustrum9.12 ± 0.23
Epithalamus9.23 ± 0.28
Frontal Lobe8.68 ± 0.32
Globus Pallidus8.53 ± 0.25
Hypothalamus9.12 ± 0.31
Insula8.89 ± 0.33
Limbic Lobe8.68 ± 0.38
Mesencephalon8.84 ± 0.29
Myelencephalon8.75 ± 0.37
Occipital Lobe8.98 ± 0.45
Parietal Lobe8.61 ± 0.25
Pontine Tegmentum8.96 ± 0.24
Striatum8.91 ± 0.32
Subthalamus8.66 ± 0.25
Temporal Lobe8.81 ± 0.31
Thalamus8.69 ± 0.25
White Matter8.42 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ssbp2CBCerebellum4.32
5.46
Ssbp2CTXCerebral cortex30.8
25.43
Ssbp2HIPHippocampal region26.35
35.91
Ssbp2HPFHippocampal formation38.08
44.27
Ssbp2HYHypothalamus10.35
8.95
Ssbp2LSXLateral septal complex8.6
6.46
Ssbp2MBMidbrain21.61
21.61
Ssbp2MYMedulla16.38
20.12
Ssbp2OLFOlfactory bulb35.7
31.31
Ssbp2PPons15.43
19.22
Ssbp2PALPallidum25.36
27.03
Ssbp2RHPRetrohippocampal region58.35
56.93
Ssbp2sAMYStriatum-like amygdalar nuclei54.58
46.66
Ssbp2STRStriatum23.76
18.97
Ssbp2STRdStriatum dorsal region16.28
12.4
Ssbp2STRvStriatum ventral region37.16
28.52
Ssbp2THThalamus3.52
3.82
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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