AutismKB 2.0

Annotation Detail for TMEM2


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Basic Information Top
Gene Symbol:TMEM2 ( - )
Gene Full Name: transmembrane protein 2
Band: 9q21.13
Quick LinksEntrez ID:23670; OMIM: 605835; Uniprot ID:TMEM2_HUMAN; ENSEMBL ID: ENSG00000135048; HGNC ID: 11869
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst5 / 6231980
fetus19 / 56401233
neonate1 / 3109732
infant0 / 236200 
juvenile5 / 5555689
adult148 / 193912176
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor3 / 3436687
chondrosarcoma4 / 8282348
colorectal tumor26 / 114246227
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor19 / 26384572
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor5 / 9635951
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal164 / 336030748
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites3 / 4001574
bladder2 / 2975767
blood3 / 12347824
bone4 / 7165555
bone marrow0 / 488010 
brain16 / 110098914
cervix3 / 4817162
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus1 / 2020949
eye3 / 21105414
heart0 / 896260 
intestine34 / 234472145
kidney4 / 21177718
larynx1 / 2414541
liver19 / 20774391
lung16 / 33697447
lymph1 / 4427022
lymph node5 / 9161054
mammary gland11 / 15327171
mouth2 / 6705229
muscle6 / 10771555
nerve2 / 15768126
ovary1 / 1020519
pancreas6 / 21481227
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta45 / 280825160
prostate6 / 18934531
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach5 / 9661951
testis19 / 33044257
thymus9 / 81131110
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218113_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.6
Adipocyte6.95
AdrenalCortex8.4
Adrenalgland6.65
Amygdala8.05
Appendix8.2
AtrioventricularNode7.25
BDCA4+_DentriticCells8.45
Bonemarrow7.75
BronchialEpithelialCells7.5
CD105+_Endothelial16.2
CD14+_Monocytes23.55
CD19+_BCells(neg._sel.)45.1
CD33+_Myeloid34.65
CD34+9.45
CD4+_Tcells10.15
CD56+_NKCells50.85
CD71+_EarlyErythroid6.5
CD8+_Tcells11.6
CardiacMyocytes12.35
Caudatenucleus6.45
Cerebellum5.65
CerebellumPeduncles9.95
CiliaryGanglion7.9
CingulateCortex7.85
Colorectaladenocarcinoma15.6
DorsalRootGanglion6.65
FetalThyroid7.1
Fetalbrain7.15
Fetalliver6.95
Fetallung95.2
GlobusPallidus6.85
Heart9.7
Hypothalamus9.35
Kidney6.95
Leukemia_chronicMyelogenousK-5626.85
Leukemia_promyelocytic-HL-606
Leukemialymphoblastic(MOLT-4)5.5
Liver10.35
Lung9.3
Lymphnode45.65
Lymphoma_burkitts(Daudi)9.4
Lymphoma_burkitts(Raji)10.4
MedullaOblongata11.75
OccipitalLobe6.95
OlfactoryBulb49.85
Ovary4.85
Pancreas9.1
PancreaticIslet12.45
ParietalLobe8.4
Pituitary8.5
Placenta324.5
Pons13.1
PrefrontalCortex9.3
Prostate8.2
Salivarygland6.6
SkeletalMuscle9.95
Skin6.3
SmoothMuscle33.05
Spinalcord7.95
SubthalamicNucleus9.35
SuperiorCervicalGanglion10
TemporalLobe6.9
Testis5.85
TestisGermCell7.8
TestisIntersitial6.25
TestisLeydigCell7.4
TestisSeminiferousTubule6.35
Thalamus7.6
Thymus15.7
Thyroid7.2
Tongue7.55
Tonsil7.5
Trachea8
TrigeminalGanglion8.3
Uterus4.95
UterusCorpus7.35
WholeBlood42.95
Wholebrain5.75
colon17.6
pineal_day8.26
pineal_night7.56
retina9.275
small_intestine11
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P94552
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.08 ± 0.59
Basal Forebrain5.88 ± 0.31
Basal Part of Pons6.4 ± 0.34
Cerebellar Cortex7.11 ± 0.23
Cerebellar Nuclei6.66 ± 0.51
Claustrum6.92 ± 0.5
Epithalamus5.72 ± 0.42
Frontal Lobe6.88 ± 0.4
Globus Pallidus5.66 ± 0.37
Hypothalamus5.82 ± 0.31
Insula6.97 ± 0.35
Limbic Lobe7.23 ± 0.53
Mesencephalon6.38 ± 0.45
Myelencephalon6.65 ± 0.53
Occipital Lobe6.46 ± 0.54
Parietal Lobe6.58 ± 0.47
Pontine Tegmentum6.72 ± 0.57
Striatum5.8 ± 0.5
Subthalamus6.25 ± 0.27
Temporal Lobe6.77 ± 0.39
Thalamus6.35 ± 0.36
White Matter5.13 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem2CBCerebellum0
0
Tmem2CTXCerebral cortex0
0
Tmem2HIPHippocampal region0
0
Tmem2HPFHippocampal formation0
0
Tmem2HYHypothalamus0
0
Tmem2LSXLateral septal complex0
0
Tmem2MBMidbrain0
0
Tmem2MYMedulla0
0
Tmem2OLFOlfactory bulb0
0
Tmem2PPons0
0
Tmem2PALPallidum0
0
Tmem2RHPRetrohippocampal region0
0
Tmem2sAMYStriatum-like amygdalar nuclei0
0
Tmem2STRStriatum0
0
Tmem2STRdStriatum dorsal region0
0
Tmem2STRvStriatum ventral region0
0
Tmem2THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00133864 13 694 706 FRPHQDANPEKPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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