AutismKB 2.0

Annotation Detail for TMEFF2


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Basic Information Top
Gene Symbol:TMEFF2 ( CT120.2,HPP1,TENB2,TPEF,TR )
Gene Full Name: transmembrane protein with EGF-like and two follistatin-like domains 2
Band: 2q32.3
Quick LinksEntrez ID:23671; OMIM: 605734; Uniprot ID:TEFF2_HUMAN; ENSEMBL ID: ENSG00000144339; HGNC ID: 11867
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus16 / 56401228
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor1 / 2638453
glioma6 / 10688356
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal86 / 336030725
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer9 / 10268087
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain81 / 110098973
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine2 / 2344728
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve2 / 15768126
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate17 / 18934589
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14044_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.41 ± 0.47
Basal Forebrain8.16 ± 0.42
Basal Part of Pons7.66 ± 0.31
Cerebellar Cortex7.89 ± 0.25
Cerebellar Nuclei8.14 ± 0.27
Claustrum7.87 ± 0.68
Epithalamus7.27 ± 1.05
Frontal Lobe8.55 ± 0.42
Globus Pallidus8.35 ± 0.68
Hypothalamus8.6 ± 0.4
Insula8.55 ± 0.46
Limbic Lobe8.19 ± 0.53
Mesencephalon8.4 ± 0.55
Myelencephalon8.15 ± 0.68
Occipital Lobe7.5 ± 0.65
Parietal Lobe8.09 ± 0.5
Pontine Tegmentum8.33 ± 0.46
Striatum7.56 ± 0.56
Subthalamus7.88 ± 0.44
Temporal Lobe8.47 ± 0.47
Thalamus8.42 ± 0.56
White Matter9.73 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmeff2CBCerebellum43.36
74.11
Tmeff2CTXCerebral cortex100
100
Tmeff2HIPHippocampal region100
100
Tmeff2HPFHippocampal formation100
100
Tmeff2HYHypothalamus100
99.48
Tmeff2LSXLateral septal complex96.7
90.07
Tmeff2MBMidbrain93.31
100
Tmeff2MYMedulla58.28
63.7
Tmeff2OLFOlfactory bulb100
100
Tmeff2PPons71.48
79.77
Tmeff2PALPallidum100
100
Tmeff2RHPRetrohippocampal region100
100
Tmeff2sAMYStriatum-like amygdalar nuclei100
100
Tmeff2STRStriatum93.93
91.87
Tmeff2STRdStriatum dorsal region89.39
85.54
Tmeff2STRvStriatum ventral region91.52
90.09
Tmeff2THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00039617 12 291 302 CDAGYTGQHCEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018