AutismKB 2.0

Annotation Detail for SDF2L1


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Basic Information Top
Gene Symbol:SDF2L1 ( - )
Gene Full Name: stromal cell-derived factor 2-like 1
Band: 22q11.21
Quick LinksEntrez ID:23753; OMIM: 607551; Uniprot ID:SDF2L_HUMAN; ENSEMBL ID: ENSG00000128228; HGNC ID: 10676
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult64 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor11 / 94178116
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor6 / 26384522
glioma2 / 10688318
head and neck tumor9 / 13630266
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor4 / 10312738
lymphoma5 / 7175569
non-neoplasia1 / 9725010
normal79 / 336030723
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer7 / 10268068
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow1 / 4880120
brain13 / 110098911
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus1 / 2020949
eye7 / 21105433
heart0 / 896260 
intestine10 / 23447242
kidney6 / 21177728
larynx3 / 24145124
liver2 / 2077439
lung9 / 33697426
lymph0 / 442700 
lymph node1 / 9161010
mammary gland12 / 15327178
mouth1 / 6705214
muscle4 / 10771537
nerve0 / 157680 
ovary4 / 10205139
pancreas26 / 214812121
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta2 / 2808257
prostate18 / 18934595
salivary gland3 / 20155148
skin3 / 21057414
spleen1 / 5395218
stomach4 / 9661941
testis7 / 33044221
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218681_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts59.3
Adipocyte12.45
AdrenalCortex11.45
Adrenalgland10.6
Amygdala13.5
Appendix12.45
AtrioventricularNode9.15
BDCA4+_DentriticCells121.55
Bonemarrow17.65
BronchialEpithelialCells26.7
CD105+_Endothelial17.45
CD14+_Monocytes21.5
CD19+_BCells(neg._sel.)16.95
CD33+_Myeloid25.75
CD34+34.75
CD4+_Tcells14.05
CD56+_NKCells75.5
CD71+_EarlyErythroid11.7
CD8+_Tcells12.55
CardiacMyocytes15.6
Caudatenucleus11.2
Cerebellum10.1
CerebellumPeduncles14.15
CiliaryGanglion7.4
CingulateCortex11.55
Colorectaladenocarcinoma14.4
DorsalRootGanglion7.8
FetalThyroid12.9
Fetalbrain12.45
Fetalliver10.9
Fetallung12.45
GlobusPallidus8.95
Heart16.3
Hypothalamus13
Kidney9.95
Leukemia_chronicMyelogenousK-562134.1
Leukemia_promyelocytic-HL-6011.15
Leukemialymphoblastic(MOLT-4)10.65
Liver158.9
Lung31.7
Lymphnode10.95
Lymphoma_burkitts(Daudi)16
Lymphoma_burkitts(Raji)17.55
MedullaOblongata11.5
OccipitalLobe9.6
OlfactoryBulb9.95
Ovary8.3
Pancreas11.45
PancreaticIslet39.8
ParietalLobe13.05
Pituitary24.9
Placenta13.85
Pons11.9
PrefrontalCortex14.5
Prostate30.55
Salivarygland10
SkeletalMuscle13.65
Skin9.25
SmoothMuscle22.9
Spinalcord13.4
SubthalamicNucleus11.25
SuperiorCervicalGanglion13.8
TemporalLobe10.5
Testis12.8
TestisGermCell10.6
TestisIntersitial10.55
TestisLeydigCell12.35
TestisSeminiferousTubule10.8
Thalamus12.7
Thymus10.15
Thyroid97
Tongue12.05
Tonsil12.3
Trachea10.7
TrigeminalGanglion12.05
Uterus10.5
UterusCorpus11.05
WholeBlood13.9
Wholebrain10.95
colon12.9
pineal_day15.7
pineal_night15.2
retina15.425
small_intestine12.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2367_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.87 ± 0.36
Basal Forebrain7 ± 0.17
Basal Part of Pons7.39 ± 0.21
Cerebellar Cortex6.97 ± 0.32
Cerebellar Nuclei7.26 ± 0.33
Claustrum6.82 ± 0.36
Epithalamus7.22 ± 0.49
Frontal Lobe7.21 ± 0.31
Globus Pallidus7.51 ± 0.13
Hypothalamus7.48 ± 0.65
Insula7.04 ± 0.45
Limbic Lobe6.94 ± 0.36
Mesencephalon7.05 ± 0.32
Myelencephalon7.14 ± 0.33
Occipital Lobe6.82 ± 0.27
Parietal Lobe7.03 ± 0.31
Pontine Tegmentum7.04 ± 0.34
Striatum7.37 ± 0.29
Subthalamus7.42 ± 0.04
Temporal Lobe7.19 ± 0.27
Thalamus7.12 ± 0.2
White Matter7.59 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sdf2l1CBCerebellum11.22
13.48
Sdf2l1CTXCerebral cortex7.29
5.48
Sdf2l1HIPHippocampal region3.12
2.96
Sdf2l1HPFHippocampal formation5.01
4.1
Sdf2l1HYHypothalamus0.84
1.04
Sdf2l1LSXLateral septal complex0.05
0
Sdf2l1MBMidbrain0.52
0.65
Sdf2l1MYMedulla2.72
3.23
Sdf2l1OLFOlfactory bulb6.26
5.5
Sdf2l1PPons0.79
1.21
Sdf2l1PALPallidum1.54
1.88
Sdf2l1RHPRetrohippocampal region8.5
5.95
Sdf2l1sAMYStriatum-like amygdalar nuclei0.33
0.15
Sdf2l1STRStriatum1.88
1.38
Sdf2l1STRdStriatum dorsal region2.43
1.86
Sdf2l1STRvStriatum ventral region1.16
0.73
Sdf2l1THThalamus2.04
2.6
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000485 15 29 43 AKTGAELVTCGSVLK Peptide Atlas
SDF2L_HUMAN_183 18 183 200 GQHEVHGMPSANTHNTWK PRIDE
SDF2L_HUMAN_201 20 201 220 AMEGIFIKPSVEPSAGHDEL PRIDE
SDF2L_HUMAN_30 13 30 42 TGAELVTCGSVLK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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