AutismKB 2.0

Annotation Detail for MAFF


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MAFF ( U-MAF,hMafF )
Gene Full Name: v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
Band: 22q13.1
Quick LinksEntrez ID:23764; OMIM: 604877; Uniprot ID:MAFF_HUMAN; ENSEMBL ID: ENSG00000185022; HGNC ID: 6780
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus3 / 5640125
neonate5 / 31097160
infant0 / 236200 
juvenile2 / 5555635
adult88 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor19 / 94178201
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor8 / 26384530
glioma1 / 1068839
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal160 / 336030747
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites1 / 4001524
bladder4 / 29757134
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain20 / 110098918
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye3 / 21105414
heart5 / 8962655
intestine8 / 23447234
kidney5 / 21177723
larynx1 / 2414541
liver1 / 2077434
lung30 / 33697489
lymph0 / 442700 
lymph node0 / 916100 
mammary gland20 / 153271130
mouth6 / 6705289
muscle1 / 1077159
nerve1 / 1576863
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta40 / 280825142
prostate5 / 18934526
salivary gland0 / 201550 
skin19 / 21057490
spleen5 / 5395292
stomach3 / 9661931
testis3 / 3304429
thymus9 / 81131110
thyroid1 / 4747321
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus7 / 23287830
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 36711_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.6
Adipocyte14.55
AdrenalCortex187.15
Adrenalgland32.15
Amygdala7.2
Appendix64.95
AtrioventricularNode7.25
BDCA4+_DentriticCells31.75
Bonemarrow7.6
BronchialEpithelialCells96.75
CD105+_Endothelial6.85
CD14+_Monocytes7.25
CD19+_BCells(neg._sel.)7.3
CD33+_Myeloid144
CD34+17.95
CD4+_Tcells6.95
CD56+_NKCells281.85
CD71+_EarlyErythroid6.5
CD8+_Tcells6.65
CardiacMyocytes11.05
Caudatenucleus6.05
Cerebellum5.45
CerebellumPeduncles8
CiliaryGanglion21.9
CingulateCortex7.1
Colorectaladenocarcinoma179.5
DorsalRootGanglion6.25
FetalThyroid6.95
Fetalbrain6.85
Fetalliver6
Fetallung172.35
GlobusPallidus5.4
Heart9.45
Hypothalamus10.1
Kidney6
Leukemia_chronicMyelogenousK-5626.25
Leukemia_promyelocytic-HL-606.35
Leukemialymphoblastic(MOLT-4)5.2
Liver9.75
Lung875.3
Lymphnode13.6
Lymphoma_burkitts(Daudi)8.85
Lymphoma_burkitts(Raji)10.1
MedullaOblongata6
OccipitalLobe5.9
OlfactoryBulb176.55
Ovary40.3
Pancreas13.5
PancreaticIslet86.8
ParietalLobe7.5
Pituitary8.05
Placenta3478.5
Pons6.6
PrefrontalCortex12.2
Prostate172.7
Salivarygland37.6
SkeletalMuscle9.3
Skin59.65
SmoothMuscle122.45
Spinalcord27.05
SubthalamicNucleus6.65
SuperiorCervicalGanglion10.8
TemporalLobe6.3
Testis5.7
TestisGermCell5.65
TestisIntersitial5.85
TestisLeydigCell7.15
TestisSeminiferousTubule5.8
Thalamus7
Thymus11.6
Thyroid59.35
Tongue8.4
Tonsil8.7
Trachea79.15
TrigeminalGanglion12.25
Uterus91.5
UterusCorpus31.2
WholeBlood12
Wholebrain5.75
colon80.2
pineal_day14.04
pineal_night38.98
retina64.425
small_intestine41
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10833_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.16 ± 0.93
Basal Forebrain2.1 ± 0.44
Basal Part of Pons1.72 ± 0.5
Cerebellar Cortex1.79 ± 0.78
Cerebellar Nuclei2.31 ± 0.76
Claustrum2.65 ± 0.91
Epithalamus2.47 ± 0.72
Frontal Lobe1.9 ± 0.78
Globus Pallidus2.18 ± 0.6
Hypothalamus2.46 ± 0.92
Insula1.99 ± 0.6
Limbic Lobe2.06 ± 0.75
Mesencephalon2.17 ± 0.8
Myelencephalon2.04 ± 0.66
Occipital Lobe2.09 ± 0.77
Parietal Lobe2.02 ± 0.73
Pontine Tegmentum2.03 ± 0.84
Striatum2.11 ± 1.13
Subthalamus2.3 ± 0.12
Temporal Lobe1.94 ± 0.72
Thalamus1.82 ± 0.72
White Matter1.95 ± 0.67
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MaffCBCerebellum42.58
53.64
MaffCTXCerebral cortex100
100
MaffHIPHippocampal region64.32
85.1
MaffHPFHippocampal formation76.83
83.08
MaffHYHypothalamus40.53
30.74
MaffLSXLateral septal complex53.26
36.05
MaffMBMidbrain62.18
52.63
MaffMYMedulla54.82
53.01
MaffOLFOlfactory bulb100
89.56
MaffPPons51.75
48.55
MaffPALPallidum42.79
35.65
MaffRHPRetrohippocampal region100
83.56
MaffsAMYStriatum-like amygdalar nuclei58.33
41.99
MaffSTRStriatum63.63
45.05
MaffSTRdStriatum dorsal region61.18
42.65
MaffSTRvStriatum ventral region77.06
55.2
MaffTHThalamus66.42
53.49
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018