AutismKB 2.0

Annotation Detail for IL17RA


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Basic Information Top
Gene Symbol:IL17RA ( CD217,CDw217,IL-17RA,IL17R,MGC10262,hIL-17R )
Gene Full Name: interleukin 17 receptor A
Band: 22q11.1
Quick LinksEntrez ID:23765; OMIM: 605461; Uniprot ID:I17RA_HUMAN; ENSEMBL ID: ENSG00000177663; HGNC ID: 5985
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate1 / 3109732
infant1 / 2362042
juvenile1 / 5555617
adult55 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor1 / 2638453
glioma3 / 10688328
head and neck tumor6 / 13630244
kidney tumor4 / 6895958
leukemia7 / 9584273
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal27 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood6 / 12347848
bone2 / 7165527
bone marrow0 / 488010 
brain17 / 110098915
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine0 / 2344720 
kidney5 / 21177723
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph0 / 442700 
lymph node2 / 9161021
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta1 / 2808253
prostate4 / 18934521
salivary gland0 / 201550 
skin2 / 2105749
spleen2 / 5395237
stomach5 / 9661951
testis0 / 3304420 
thymus4 / 8113149
thyroid5 / 47473105
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205707_at
Cell line Expression level Expression bar
721_B_lymphoblasts22.2
Adipocyte22.9
AdrenalCortex18.5
Adrenalgland19.8
Amygdala20.85
Appendix18.25
AtrioventricularNode15.1
BDCA4+_DentriticCells40.1
Bonemarrow34.9
BronchialEpithelialCells17.2
CD105+_Endothelial20.9
CD14+_Monocytes189.65
CD19+_BCells(neg._sel.)19.7
CD33+_Myeloid378.9
CD34+30.9
CD4+_Tcells68.8
CD56+_NKCells33.2
CD71+_EarlyErythroid16.3
CD8+_Tcells79
CardiacMyocytes25.35
Caudatenucleus32.9
Cerebellum16.5
CerebellumPeduncles23.15
CiliaryGanglion13.95
CingulateCortex20.85
Colorectaladenocarcinoma19.15
DorsalRootGanglion13.35
FetalThyroid27.7
Fetalbrain21.15
Fetalliver16.6
Fetallung18.6
GlobusPallidus14.75
Heart20.1
Hypothalamus22.6
Kidney20.2
Leukemia_chronicMyelogenousK-56220.05
Leukemia_promyelocytic-HL-6015.6
Leukemialymphoblastic(MOLT-4)25.05
Liver26.75
Lung33.15
Lymphnode27.1
Lymphoma_burkitts(Daudi)36.35
Lymphoma_burkitts(Raji)28.3
MedullaOblongata18.9
OccipitalLobe24.95
OlfactoryBulb16.25
Ovary13.45
Pancreas16.45
PancreaticIslet24.05
ParietalLobe21.25
Pituitary27.4
Placenta21.55
Pons31.05
PrefrontalCortex22.95
Prostate38.65
Salivarygland16.3
SkeletalMuscle22.55
Skin13.15
SmoothMuscle23.55
Spinalcord25.05
SubthalamicNucleus18.45
SuperiorCervicalGanglion20.75
TemporalLobe25.35
Testis17.9
TestisGermCell17.35
TestisIntersitial14.25
TestisLeydigCell20.2
TestisSeminiferousTubule30.7
Thalamus20.8
Thymus52.35
Thyroid26
Tongue19.75
Tonsil21.95
Trachea17.2
TrigeminalGanglion20.9
Uterus15.55
UterusCorpus17.95
WholeBlood86.25
Wholebrain17.85
colon16.95
pineal_day19.36
pineal_night17.96
retina25.2
small_intestine18.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12784_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.55 ± 0.95
Basal Forebrain4.04 ± 0.7
Basal Part of Pons4.18 ± 0.67
Cerebellar Cortex3.35 ± 0.49
Cerebellar Nuclei4.47 ± 0.55
Claustrum4.18 ± 0.79
Epithalamus3.89 ± 0.46
Frontal Lobe3.67 ± 0.77
Globus Pallidus4.88 ± 0.44
Hypothalamus3.39 ± 0.57
Insula3.43 ± 0.63
Limbic Lobe4.18 ± 1.02
Mesencephalon4.09 ± 0.75
Myelencephalon4.06 ± 0.76
Occipital Lobe4.64 ± 0.76
Parietal Lobe4.1 ± 0.83
Pontine Tegmentum4.08 ± 1.09
Striatum6.41 ± 0.71
Subthalamus3.96 ± 1.05
Temporal Lobe3.99 ± 0.65
Thalamus3.72 ± 0.64
White Matter5.37 ± 0.56
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Il17raCBCerebellum1.27
1.92
Il17raCTXCerebral cortex11.93
8.41
Il17raHIPHippocampal region0.4
0.38
Il17raHPFHippocampal formation0.9
1.24
Il17raHYHypothalamus0.11
0.11
Il17raLSXLateral septal complex0.04
0
Il17raMBMidbrain0.24
0.31
Il17raMYMedulla0.38
0.46
Il17raOLFOlfactory bulb1.44
1.6
Il17raPPons0.46
0.59
Il17raPALPallidum0.07
0.09
Il17raRHPRetrohippocampal region1.51
2.05
Il17rasAMYStriatum-like amygdalar nuclei0.14
0.13
Il17raSTRStriatum0.2
0.16
Il17raSTRdStriatum dorsal region0.23
0.21
Il17raSTRvStriatum ventral region0.12
0.09
Il17raTHThalamus0.24
0.29
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00029152 23 469 491 CDHGKPVGDLFTAAMNMILPDFK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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