AutismKB 2.0

Annotation Detail for FLRT3


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Basic Information Top
Gene Symbol:FLRT3 ( - )
Gene Full Name: fibronectin leucine rich transmembrane protein 3
Band: 20p12.1
Quick LinksEntrez ID:23767; OMIM: 604808; Uniprot ID:FLRT3_HUMAN; ENSEMBL ID: ENSG00000125848; HGNC ID: 3762
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst2 / 6231932
fetus35 / 56401262
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor14 / 26384553
glioma0 / 1068830 
head and neck tumor4 / 13630229
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal85 / 336030725
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain34 / 110098930
cervix0 / 481710 
connective tissue2 / 14925513
ear7 / 16212431
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye0 / 2110540 
heart5 / 8962655
intestine0 / 2344720 
kidney12 / 21177756
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth4 / 6705259
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach2 / 9661920
testis15 / 33044245
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219250_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.6
Adipocyte4.15
AdrenalCortex4.9
Adrenalgland3.8
Amygdala6
Appendix5.45
AtrioventricularNode4.05
BDCA4+_DentriticCells4.65
Bonemarrow4.45
BronchialEpithelialCells101.35
CD105+_Endothelial4.4
CD14+_Monocytes4.5
CD19+_BCells(neg._sel.)4.6
CD33+_Myeloid5.45
CD34+5.25
CD4+_Tcells4.85
CD56+_NKCells5.3
CD71+_EarlyErythroid4.25
CD8+_Tcells4.15
CardiacMyocytes6
Caudatenucleus3.8
Cerebellum3.65
CerebellumPeduncles5.9
CiliaryGanglion3.75
CingulateCortex10.1
Colorectaladenocarcinoma4.4
DorsalRootGanglion3.9
FetalThyroid5.2
Fetalbrain4.75
Fetalliver38.8
Fetallung11.5
GlobusPallidus3.85
Heart5.9
Hypothalamus5
Kidney5
Leukemia_chronicMyelogenousK-5623.9
Leukemia_promyelocytic-HL-603.85
Leukemialymphoblastic(MOLT-4)3.35
Liver6.1
Lung4.75
Lymphnode3.85
Lymphoma_burkitts(Daudi)5.7
Lymphoma_burkitts(Raji)6.4
MedullaOblongata4.15
OccipitalLobe6.35
OlfactoryBulb4
Ovary3.4
Pancreas3.7
PancreaticIslet15.5
ParietalLobe6
Pituitary5.25
Placenta4.3
Pons4.3
PrefrontalCortex8.55
Prostate13.85
Salivarygland3.65
SkeletalMuscle5.75
Skin3.85
SmoothMuscle4.75
Spinalcord4.8
SubthalamicNucleus5.1
SuperiorCervicalGanglion6.95
TemporalLobe6.35
Testis3.7
TestisGermCell3.65
TestisIntersitial3.75
TestisLeydigCell5
TestisSeminiferousTubule3.85
Thalamus4.6
Thymus3.55
Thyroid5.75
Tongue4.5
Tonsil4.3
Trachea3.75
TrigeminalGanglion6.8
Uterus3.65
UterusCorpus4.4
WholeBlood4.7
Wholebrain4.2
colon4.6
pineal_day5.66
pineal_night6.04
retina5.5
small_intestine4.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6136_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.07 ± 0.79
Basal Forebrain5.55 ± 0.58
Basal Part of Pons4.89 ± 0.53
Cerebellar Cortex6.97 ± 0.2
Cerebellar Nuclei5.46 ± 0.77
Claustrum5.69 ± 0.63
Epithalamus6.1 ± 0.66
Frontal Lobe6.42 ± 0.68
Globus Pallidus4.24 ± 0.75
Hypothalamus6.14 ± 0.61
Insula6.75 ± 0.29
Limbic Lobe6.47 ± 1.03
Mesencephalon6.13 ± 0.72
Myelencephalon6.07 ± 0.7
Occipital Lobe6.02 ± 0.62
Parietal Lobe6.38 ± 0.71
Pontine Tegmentum6.48 ± 0.81
Striatum4.6 ± 0.84
Subthalamus5.45 ± 0.95
Temporal Lobe6.63 ± 0.49
Thalamus5.87 ± 0.62
White Matter4.99 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Flrt3CBCerebellum19.59
19.76
Flrt3CTXCerebral cortex33.55
28.11
Flrt3HIPHippocampal region32.14
63.83
Flrt3HPFHippocampal formation37.91
54.41
Flrt3HYHypothalamus17.89
15.06
Flrt3LSXLateral septal complex24.84
20.24
Flrt3MBMidbrain15.51
14.11
Flrt3MYMedulla11.93
12.05
Flrt3OLFOlfactory bulb30.15
26.62
Flrt3PPons17.26
16.67
Flrt3PALPallidum29.11
28.09
Flrt3RHPRetrohippocampal region47.31
45.72
Flrt3sAMYStriatum-like amygdalar nuclei25.68
21.03
Flrt3STRStriatum66.59
55.66
Flrt3STRdStriatum dorsal region71.34
59.1
Flrt3STRvStriatum ventral region90.47
75.94
Flrt3THThalamus9.17
12.76
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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