AutismKB 2.0

Annotation Detail for FLRT2


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Basic Information Top
Gene Symbol:FLRT2 ( KIAA0405 )
Gene Full Name: fibronectin leucine rich transmembrane protein 2
Band: 14q31.3
Quick LinksEntrez ID:23768; OMIM: 604807; Uniprot ID:FLRT2_HUMAN; ENSEMBL ID: ENSG00000185070; HGNC ID: 3761
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst0 / 623190 
fetus129 / 564012228
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult55 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal250 / 336030774
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites0 / 400150 
bladder2 / 2975767
blood0 / 1234780 
bone8 / 71655111
bone marrow0 / 488010 
brain105 / 110098995
cervix0 / 481710 
connective tissue10 / 14925566
ear11 / 16212678
embryonic tissue19 / 21572288
esophagus0 / 202090 
eye15 / 21105471
heart16 / 89626178
intestine3 / 23447212
kidney4 / 21177718
larynx0 / 241450 
liver2 / 2077439
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth3 / 6705244
muscle4 / 10771537
nerve2 / 15768126
ovary4 / 10205139
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate8 / 18934542
salivary gland0 / 201550 
skin4 / 21057418
spleen1 / 5395218
stomach3 / 9661931
testis10 / 33044230
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord1 / 1368073
uterus7 / 23287830
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204358_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.9
Adipocyte7
AdrenalCortex4.2
Adrenalgland3.3
Amygdala5.05
Appendix4
AtrioventricularNode4.65
BDCA4+_DentriticCells4.35
Bonemarrow3.8
BronchialEpithelialCells3.9
CD105+_Endothelial4
CD14+_Monocytes4.2
CD19+_BCells(neg._sel.)4.15
CD33+_Myeloid5.05
CD34+5.1
CD4+_Tcells4.3
CD56+_NKCells4.7
CD71+_EarlyErythroid3.65
CD8+_Tcells3.75
CardiacMyocytes7.7
Caudatenucleus3.6
Cerebellum3.15
CerebellumPeduncles4.45
CiliaryGanglion2.8
CingulateCortex6.25
Colorectaladenocarcinoma3.95
DorsalRootGanglion3.05
FetalThyroid4.05
Fetalbrain4.3
Fetalliver3.4
Fetallung3.15
GlobusPallidus3.45
Heart5
Hypothalamus4.3
Kidney3.2
Leukemia_chronicMyelogenousK-5623.55
Leukemia_promyelocytic-HL-603.65
Leukemialymphoblastic(MOLT-4)3.1
Liver5.2
Lung4.3
Lymphnode3.4
Lymphoma_burkitts(Daudi)5
Lymphoma_burkitts(Raji)5.45
MedullaOblongata3.7
OccipitalLobe4
OlfactoryBulb4.05
Ovary2.6
Pancreas3.3
PancreaticIslet4.2
ParietalLobe5.35
Pituitary4.7
Placenta4
Pons3.75
PrefrontalCortex11.85
Prostate4.7
Salivarygland4.1
SkeletalMuscle4.7
Skin3.05
SmoothMuscle4.35
Spinalcord4.2
SubthalamicNucleus3.75
SuperiorCervicalGanglion6.3
TemporalLobe6
Testis3.35
TestisGermCell3.4
TestisIntersitial3.3
TestisLeydigCell3.9
TestisSeminiferousTubule3.4
Thalamus4
Thymus3.1
Thyroid4.95
Tongue4.7
Tonsil3.8
Trachea3.35
TrigeminalGanglion3.9
Uterus3.2
UterusCorpus3.55
WholeBlood4.2
Wholebrain4.2
colon3.95
pineal_day4.94
pineal_night4.84
retina5.925
small_intestine3.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P99802
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.84 ± 0.36
Basal Forebrain9.89 ± 0.31
Basal Part of Pons8.6 ± 0.34
Cerebellar Cortex8.98 ± 0.3
Cerebellar Nuclei8.85 ± 0.6
Claustrum9.73 ± 0.37
Epithalamus8.94 ± 0.62
Frontal Lobe9.71 ± 0.54
Globus Pallidus9.5 ± 0.7
Hypothalamus9.09 ± 0.64
Insula9.71 ± 0.4
Limbic Lobe9.78 ± 0.52
Mesencephalon9.65 ± 0.59
Myelencephalon9.65 ± 0.63
Occipital Lobe10.52 ± 0.45
Parietal Lobe9.99 ± 0.49
Pontine Tegmentum10.05 ± 0.38
Striatum9.61 ± 0.79
Subthalamus9.08 ± 0.32
Temporal Lobe9.78 ± 0.57
Thalamus9.75 ± 0.43
White Matter7.72 ± 0.85
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Flrt2CBCerebellum26.73
34.86
Flrt2CTXCerebral cortex80.39
74.85
Flrt2HIPHippocampal region35.96
52.76
Flrt2HPFHippocampal formation41.71
50.61
Flrt2HYHypothalamus13.3
10.66
Flrt2LSXLateral septal complex56.07
46.1
Flrt2MBMidbrain12.06
12.72
Flrt2MYMedulla21.67
26.08
Flrt2OLFOlfactory bulb42.38
46.22
Flrt2PPons13.4
14.57
Flrt2PALPallidum18.38
18.02
Flrt2RHPRetrohippocampal region54.01
50.03
Flrt2sAMYStriatum-like amygdalar nuclei15.13
11.18
Flrt2STRStriatum24.48
21.94
Flrt2STRdStriatum dorsal region17.43
15.39
Flrt2STRvStriatum ventral region43.65
41.18
Flrt2THThalamus23.7
22.46
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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