AutismKB 2.0

Annotation Detail for FKBP8


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Basic Information Top
Gene Symbol:FKBP8 ( FKBP38,FKBPr38 )
Gene Full Name: FK506 binding protein 8, 38kDa
Band: 19p13.11
Quick LinksEntrez ID:23770; OMIM: 604840; Uniprot ID:FKBP8_HUMAN; ENSEMBL ID: ENSG00000105701; HGNC ID: 3724
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body14 / 70761197
blastocyst9 / 62319144
fetus50 / 56401288
neonate0 / 310970 
infant2 / 2362084
juvenile7 / 55556125
adult262 / 1939121135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor25 / 94178265
cervical tumor4 / 34366116
chondrosarcoma13 / 82823156
colorectal tumor6 / 11424652
esophageal tumor3 / 17290173
gastrointestinal tumor17 / 119369142
germ cell tumor38 / 263845144
glioma37 / 106883346
head and neck tumor39 / 136302286
kidney tumor13 / 68959188
leukemia16 / 95842166
liver tumor28 / 96359290
lung tumor57 / 103127552
lymphoma43 / 71755599
non-neoplasia7 / 9725071
normal362 / 3360307107
ovarian tumor4 / 7668252
pancreatic tumor45 / 104616430
primitive neuroectodermal tumor of the CNS37 / 125680294
prostate cancer30 / 102680292
retinoblastoma15 / 46356323
skin tumor25 / 124949200
soft tissue/muscle tissue tumor33 / 125191263
uterine tumor13 / 90257144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland4 / 33197120
ascites8 / 40015199
bladder3 / 29757100
blood26 / 123478210
bone12 / 71655167
bone marrow1 / 4880120
brain149 / 1100989135
cervix6 / 48171124
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue39 / 215722180
esophagus3 / 20209148
eye53 / 211054251
heart8 / 8962689
intestine14 / 23447259
kidney19 / 21177789
larynx1 / 2414541
liver28 / 207743134
lung82 / 336974243
lymph39 / 44270880
lymph node6 / 9161065
mammary gland28 / 153271182
mouth1 / 6705214
muscle14 / 107715129
nerve4 / 15768253
ovary17 / 102051166
pancreas54 / 214812251
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta28 / 28082599
prostate32 / 189345169
salivary gland31 / 201551538
skin35 / 210574166
spleen8 / 53952148
stomach3 / 9661931
testis40 / 330442121
thymus8 / 8113198
thyroid6 / 47473126
tonsil3 / 16999176
trachea1 / 5241319
umbilical cord0 / 136800 
uterus35 / 232878150
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 40850_at
Cell line Expression level Expression bar
721_B_lymphoblasts30.45
Adipocyte27.6
AdrenalCortex20.85
Adrenalgland15.15
Amygdala90.8
Appendix19.9
AtrioventricularNode14.75
BDCA4+_DentriticCells16.1
Bonemarrow49.65
BronchialEpithelialCells20.45
CD105+_Endothelial14.65
CD14+_Monocytes27.3
CD19+_BCells(neg._sel.)22
CD33+_Myeloid21.55
CD34+19.5
CD4+_Tcells16.7
CD56+_NKCells19.95
CD71+_EarlyErythroid202.35
CD8+_Tcells15.05
CardiacMyocytes19.9
Caudatenucleus55.95
Cerebellum40.75
CerebellumPeduncles43.4
CiliaryGanglion14.75
CingulateCortex55.85
Colorectaladenocarcinoma25
DorsalRootGanglion14.05
FetalThyroid19.3
Fetalbrain21
Fetalliver17.6
Fetallung22.75
GlobusPallidus27.3
Heart37.05
Hypothalamus47.75
Kidney19.1
Leukemia_chronicMyelogenousK-56222.45
Leukemia_promyelocytic-HL-6016.6
Leukemialymphoblastic(MOLT-4)26.65
Liver29.5
Lung41.7
Lymphnode17
Lymphoma_burkitts(Daudi)12.3
Lymphoma_burkitts(Raji)40.8
MedullaOblongata108.5
OccipitalLobe31.7
OlfactoryBulb22
Ovary12.6
Pancreas11.5
PancreaticIslet16.75
ParietalLobe39.1
Pituitary22.65
Placenta22.25
Pons42.15
PrefrontalCortex308.05
Prostate37.95
Salivarygland10.55
SkeletalMuscle34.75
Skin14.5
SmoothMuscle27.9
Spinalcord36.7
SubthalamicNucleus57.9
SuperiorCervicalGanglion22.05
TemporalLobe95.85
Testis29.4
TestisGermCell68
TestisIntersitial31.3
TestisLeydigCell27.4
TestisSeminiferousTubule39.9
Thalamus19.05
Thymus17.6
Thyroid37.65
Tongue19.55
Tonsil15.7
Trachea17.2
TrigeminalGanglion19.6
Uterus13.4
UterusCorpus16.6
WholeBlood143.5
Wholebrain87.4
colon10.2
pineal_day40.72
pineal_night32.4
retina24.3
small_intestine9.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14627_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.78 ± 0.42
Basal Forebrain8.47 ± 0.22
Basal Part of Pons8.98 ± 0.25
Cerebellar Cortex8.2 ± 0.22
Cerebellar Nuclei8.3 ± 0.38
Claustrum9.05 ± 0.48
Epithalamus7.84 ± 0.33
Frontal Lobe8.44 ± 0.39
Globus Pallidus8.34 ± 0.27
Hypothalamus8.23 ± 0.53
Insula8.41 ± 0.52
Limbic Lobe8.78 ± 0.38
Mesencephalon8.37 ± 0.28
Myelencephalon8.56 ± 0.38
Occipital Lobe8.94 ± 0.34
Parietal Lobe8.66 ± 0.37
Pontine Tegmentum8.4 ± 0.39
Striatum8.97 ± 0.33
Subthalamus8.49 ± 0.03
Temporal Lobe8.57 ± 0.37
Thalamus8.46 ± 0.35
White Matter7.96 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fkbp8CBCerebellum16
20.95
Fkbp8CTXCerebral cortex24.25
20.98
Fkbp8HIPHippocampal region27.26
52.02
Fkbp8HPFHippocampal formation29.81
42.86
Fkbp8HYHypothalamus2.48
2.52
Fkbp8LSXLateral septal complex1.86
1.41
Fkbp8MBMidbrain2.99
3.87
Fkbp8MYMedulla13.26
18.92
Fkbp8OLFOlfactory bulb26.74
25.34
Fkbp8PPons8.45
12.38
Fkbp8PALPallidum6.34
7.9
Fkbp8RHPRetrohippocampal region34.25
32.04
Fkbp8sAMYStriatum-like amygdalar nuclei10.2
8.64
Fkbp8STRStriatum12.57
10.93
Fkbp8STRdStriatum dorsal region14.29
12.59
Fkbp8STRvStriatum ventral region12.78
10.54
Fkbp8THThalamus3.6
4.63
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001170 11 275 285 CLNNLAASQLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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