AutismKB 2.0

Annotation Detail for BRD1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:BRD1 ( BRL,BRPF1,BRPF2,DKFZp686F0325 )
Gene Full Name: bromodomain containing 1
Band: 22q13.33
Quick LinksEntrez ID:23774; OMIM: 604589; Uniprot ID:BRD1_HUMAN; ENSEMBL ID: ENSG00000100425; HGNC ID: 1102
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult53 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor5 / 26384518
glioma4 / 10688337
head and neck tumor6 / 13630244
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal80 / 336030723
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer10 / 10268097
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain18 / 110098916
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus1 / 2020949
eye11 / 21105452
heart2 / 8962622
intestine4 / 23447217
kidney3 / 21177714
larynx1 / 2414541
liver5 / 20774324
lung3 / 3369748
lymph0 / 442700 
lymph node3 / 9161032
mammary gland5 / 15327132
mouth3 / 6705244
muscle2 / 10771518
nerve1 / 1576863
ovary3 / 10205129
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate11 / 18934558
salivary gland1 / 2015549
skin6 / 21057428
spleen1 / 5395218
stomach1 / 9661910
testis18 / 33044254
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204520_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts70
Adipocyte17.75
AdrenalCortex23.55
Adrenalgland17.25
Amygdala38.55
Appendix22.55
AtrioventricularNode20.65
BDCA4+_DentriticCells183.05
Bonemarrow21.95
BronchialEpithelialCells17.7
CD105+_Endothelial129.4
CD14+_Monocytes134.55
CD19+_BCells(neg._sel.)167.9
CD33+_Myeloid123.45
CD34+220.65
CD4+_Tcells348.75
CD56+_NKCells293.3
CD71+_EarlyErythroid78.75
CD8+_Tcells281.85
CardiacMyocytes24.9
Caudatenucleus9.75
Cerebellum62.9
CerebellumPeduncles55.45
CiliaryGanglion14.75
CingulateCortex26.25
Colorectaladenocarcinoma34.3
DorsalRootGanglion18.7
FetalThyroid56.1
Fetalbrain48.9
Fetalliver13.9
Fetallung18.35
GlobusPallidus14.45
Heart25.8
Hypothalamus28
Kidney13.45
Leukemia_chronicMyelogenousK-56219.2
Leukemia_promyelocytic-HL-6022.35
Leukemialymphoblastic(MOLT-4)39.85
Liver30
Lung151.65
Lymphnode21.55
Lymphoma_burkitts(Daudi)24.9
Lymphoma_burkitts(Raji)46.45
MedullaOblongata15.55
OccipitalLobe11.75
OlfactoryBulb16.85
Ovary15.15
Pancreas16.8
PancreaticIslet24.1
ParietalLobe15.05
Pituitary23.85
Placenta39.4
Pons21.75
PrefrontalCortex37.55
Prostate269.9
Salivarygland32.6
SkeletalMuscle24
Skin24.15
SmoothMuscle23.4
Spinalcord25.45
SubthalamicNucleus17.45
SuperiorCervicalGanglion26.15
TemporalLobe20.35
Testis307
TestisGermCell191.65
TestisIntersitial219.15
TestisLeydigCell91.5
TestisSeminiferousTubule105.7
Thalamus19.85
Thymus67.1
Thyroid66.8
Tongue18.25
Tonsil20.95
Trachea19.25
TrigeminalGanglion20.6
Uterus111.5
UterusCorpus17.75
WholeBlood60.85
Wholebrain29.4
colon48
pineal_day111.64
pineal_night149.42
retina190.275
small_intestine71.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1164_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.15 ± 0.32
Basal Forebrain4.88 ± 0.08
Basal Part of Pons4.82 ± 0.57
Cerebellar Cortex5.27 ± 0.24
Cerebellar Nuclei4.38 ± 0.51
Claustrum5.06 ± 0.72
Epithalamus4.78 ± 0.42
Frontal Lobe4.62 ± 0.53
Globus Pallidus4.96 ± 0.4
Hypothalamus4.6 ± 0.57
Insula4.92 ± 0.6
Limbic Lobe5.15 ± 0.58
Mesencephalon4.71 ± 0.59
Myelencephalon4.84 ± 0.53
Occipital Lobe5.39 ± 0.62
Parietal Lobe4.8 ± 0.44
Pontine Tegmentum4.79 ± 0.56
Striatum4.97 ± 0.52
Subthalamus4.87 ± 0.1
Temporal Lobe4.81 ± 0.53
Thalamus4.81 ± 0.37
White Matter5.78 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Brd1CBCerebellum1.5
2.56
Brd1CTXCerebral cortex5.4
2.3
Brd1HIPHippocampal region1.86
1.69
Brd1HPFHippocampal formation1.38
1.15
Brd1HYHypothalamus4.36
1.51
Brd1LSXLateral septal complex4.89
1.61
Brd1MBMidbrain2.71
1.68
Brd1MYMedulla1.63
0.82
Brd1OLFOlfactory bulb2.35
1.26
Brd1PPons2.27
1.15
Brd1PALPallidum0.93
0.6
Brd1RHPRetrohippocampal region0.65
0.47
Brd1sAMYStriatum-like amygdalar nuclei0.31
0.35
Brd1STRStriatum0.76
0.5
Brd1STRdStriatum dorsal region0.46
0.5
Brd1STRvStriatum ventral region0.55
0.29
Brd1THThalamus2.23
0.98
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003574 20 884 903 HTLEDRSELISCIENGNYAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved