AutismKB 2.0

Annotation Detail for BCL2L13


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Basic Information Top
Gene Symbol:BCL2L13 ( BCL-RAMBO,Bcl2-L-13,MIL1 )
Gene Full Name: BCL2-like 13 (apoptosis facilitator)
Band: 22q11.21
Quick LinksEntrez ID:23786; OMIM: NA; Uniprot ID:B2L13_HUMAN; ENSEMBL ID: ENSG00000099968; HGNC ID: 17164
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst5 / 6231980
fetus55 / 56401297
neonate2 / 3109764
infant3 / 23620127
juvenile2 / 5555635
adult165 / 193912185
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor12 / 94178127
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor12 / 114246105
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor28 / 263845106
glioma11 / 106883102
head and neck tumor7 / 13630251
kidney tumor5 / 6895972
leukemia11 / 95842114
liver tumor0 / 963590 
lung tumor14 / 103127135
lymphoma8 / 71755111
non-neoplasia11 / 97250113
normal282 / 336030783
ovarian tumor3 / 7668239
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS17 / 125680135
prostate cancer6 / 10268058
retinoblastoma3 / 4635664
skin tumor18 / 124949144
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites0 / 400150 
bladder2 / 2975767
blood10 / 12347880
bone2 / 7165527
bone marrow2 / 4880140
brain61 / 110098955
cervix5 / 48171103
connective tissue8 / 14925553
ear2 / 16212123
embryonic tissue16 / 21572274
esophagus1 / 2020949
eye38 / 211054180
heart10 / 89626111
intestine20 / 23447285
kidney16 / 21177775
larynx0 / 241450 
liver4 / 20774319
lung32 / 33697494
lymph5 / 44270112
lymph node7 / 9161076
mammary gland17 / 153271110
mouth7 / 67052104
muscle11 / 107715102
nerve2 / 15768126
ovary6 / 10205158
pancreas12 / 21481255
parathyroid3 / 20539146
pharynx3 / 4132872
pituitary gland1 / 1658560
placenta29 / 280825103
prostate16 / 18934584
salivary gland0 / 201550 
skin29 / 210574137
spleen3 / 5395255
stomach1 / 9661910
testis31 / 33044293
thymus6 / 8113173
thyroid1 / 4747321
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus16 / 23287868
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217955_at
Cell line Expression level Expression bar
721_B_lymphoblasts105.15
Adipocyte47.2
AdrenalCortex38.65
Adrenalgland64.95
Amygdala33.35
Appendix39.25
AtrioventricularNode33.45
BDCA4+_DentriticCells141.35
Bonemarrow35.35
BronchialEpithelialCells36.95
CD105+_Endothelial51.6
CD14+_Monocytes127.4
CD19+_BCells(neg._sel.)104.7
CD33+_Myeloid251.1
CD34+130.65
CD4+_Tcells46.8
CD56+_NKCells110.55
CD71+_EarlyErythroid148.05
CD8+_Tcells43.3
CardiacMyocytes48.9
Caudatenucleus23.05
Cerebellum21.3
CerebellumPeduncles43.35
CiliaryGanglion25.1
CingulateCortex29.35
Colorectaladenocarcinoma48.5
DorsalRootGanglion26.5
FetalThyroid37.3
Fetalbrain19.6
Fetalliver34.75
Fetallung18.3
GlobusPallidus14.9
Heart47.35
Hypothalamus40
Kidney51.55
Leukemia_chronicMyelogenousK-56260.25
Leukemia_promyelocytic-HL-6032.2
Leukemialymphoblastic(MOLT-4)16.95
Liver47.05
Lung57.1
Lymphnode27.05
Lymphoma_burkitts(Daudi)37.4
Lymphoma_burkitts(Raji)33.4
MedullaOblongata24.9
OccipitalLobe23.25
OlfactoryBulb26.2
Ovary23.35
Pancreas21.1
PancreaticIslet68.05
ParietalLobe35.7
Pituitary52.5
Placenta74.1
Pons19.95
PrefrontalCortex44
Prostate44.15
Salivarygland27.4
SkeletalMuscle45.8
Skin25.8
SmoothMuscle66.7
Spinalcord47.95
SubthalamicNucleus22.75
SuperiorCervicalGanglion48.75
TemporalLobe25.8
Testis73.6
TestisGermCell45.3
TestisIntersitial27.4
TestisLeydigCell42.05
TestisSeminiferousTubule27.2
Thalamus36.7
Thymus33.9
Thyroid49.35
Tongue41.1
Tonsil27.85
Trachea25.1
TrigeminalGanglion42.7
Uterus19.05
UterusCorpus21.45
WholeBlood47.35
Wholebrain26.65
colon52.25
pineal_day1151.94
pineal_night987.74
retina340.925
small_intestine51.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P409494
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.22 ± 0.31
Basal Forebrain7.16 ± 0.32
Basal Part of Pons7.13 ± 0.23
Cerebellar Cortex7.38 ± 0.23
Cerebellar Nuclei7.13 ± 0.19
Claustrum7.22 ± 0.37
Epithalamus7.12 ± 0.19
Frontal Lobe7.07 ± 0.27
Globus Pallidus7.01 ± 0.26
Hypothalamus7 ± 0.36
Insula7.14 ± 0.36
Limbic Lobe7.26 ± 0.24
Mesencephalon7.08 ± 0.3
Myelencephalon7.17 ± 0.26
Occipital Lobe7.35 ± 0.26
Parietal Lobe7.17 ± 0.25
Pontine Tegmentum7.16 ± 0.3
Striatum7.12 ± 0.26
Subthalamus6.7 ± 0.34
Temporal Lobe7.16 ± 0.25
Thalamus7.15 ± 0.3
White Matter6.97 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Bcl2l13LSXLateral septal complex0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
B2L13_HUMAN_313 20 313 332 EEVPEGMEEAAVASVVLPAR PRIDE
PAp00003583 25 86 110 HTSPVFSPANPESSMEDCLAHLGEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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