AutismKB 2.0

Annotation Detail for MTCH2


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Basic Information Top
Gene Symbol:MTCH2 ( MIMP )
Gene Full Name: mitochondrial carrier homolog 2 (C. elegans)
Band: 11p11.2
Quick LinksEntrez ID:23788; OMIM: 613221; Uniprot ID:MTCH2_HUMAN; ENSEMBL ID: ENSG00000109919; HGNC ID: 17587
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body12 / 70761169
blastocyst2 / 6231932
fetus31 / 56401254
neonate3 / 3109796
infant0 / 236200 
juvenile5 / 5555689
adult171 / 193912188
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma4 / 17475228
breast (mammary gland) tumor6 / 9417863
cervical tumor7 / 34366203
chondrosarcoma10 / 82823120
colorectal tumor8 / 11424670
esophageal tumor1 / 1729057
gastrointestinal tumor11 / 11936992
germ cell tumor13 / 26384549
glioma16 / 106883149
head and neck tumor15 / 136302110
kidney tumor4 / 6895958
leukemia13 / 95842135
liver tumor5 / 9635951
lung tumor8 / 10312777
lymphoma10 / 71755139
non-neoplasia8 / 9725082
normal259 / 336030777
ovarian tumor7 / 7668291
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer13 / 102680126
retinoblastoma5 / 46356107
skin tumor13 / 124949104
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites5 / 40015124
bladder6 / 29757201
blood15 / 123478121
bone8 / 71655111
bone marrow3 / 4880161
brain109 / 110098999
cervix7 / 48171145
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue22 / 215722101
esophagus1 / 2020949
eye19 / 21105490
heart5 / 8962655
intestine13 / 23447255
kidney38 / 211777179
larynx0 / 241450 
liver13 / 20774362
lung26 / 33697477
lymph5 / 44270112
lymph node0 / 916100 
mammary gland7 / 15327145
mouth0 / 670520 
muscle4 / 10771537
nerve1 / 1576863
ovary10 / 10205197
pancreas15 / 21481269
parathyroid1 / 2053948
pharynx8 / 41328193
pituitary gland0 / 165850 
placenta18 / 28082564
prostate18 / 18934595
salivary gland1 / 2015549
skin19 / 21057490
spleen1 / 5395218
stomach5 / 9661951
testis48 / 330442145
thymus1 / 8113112
thyroid13 / 47473273
tonsil1 / 1699958
trachea3 / 5241357
umbilical cord2 / 13680146
uterus28 / 232878120
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217772_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts931.85
Adipocyte194.25
AdrenalCortex37.35
Adrenalgland49.95
Amygdala56.85
Appendix36.85
AtrioventricularNode28.25
BDCA4+_DentriticCells206.15
Bonemarrow80.65
BronchialEpithelialCells341.7
CD105+_Endothelial449.05
CD14+_Monocytes184.45
CD19+_BCells(neg._sel.)82.25
CD33+_Myeloid260.35
CD34+371.3
CD4+_Tcells70.25
CD56+_NKCells183.4
CD71+_EarlyErythroid266.75
CD8+_Tcells60.1
CardiacMyocytes104.6
Caudatenucleus34.1
Cerebellum47.55
CerebellumPeduncles43.95
CiliaryGanglion25.9
CingulateCortex36.65
Colorectaladenocarcinoma62.25
DorsalRootGanglion27.9
FetalThyroid51.1
Fetalbrain51.4
Fetalliver107.3
Fetallung50
GlobusPallidus34.5
Heart104.85
Hypothalamus55.15
Kidney127.75
Leukemia_chronicMyelogenousK-56295.2
Leukemia_promyelocytic-HL-60251
Leukemialymphoblastic(MOLT-4)197.55
Liver304.15
Lung54.4
Lymphnode29.9
Lymphoma_burkitts(Daudi)255.4
Lymphoma_burkitts(Raji)64.6
MedullaOblongata33.2
OccipitalLobe53.5
OlfactoryBulb27.7
Ovary23.5
Pancreas55.65
PancreaticIslet69.7
ParietalLobe38.75
Pituitary46.85
Placenta70.25
Pons34.1
PrefrontalCortex56.45
Prostate43.45
Salivarygland41.3
SkeletalMuscle41.8
Skin31.05
SmoothMuscle256.45
Spinalcord41.7
SubthalamicNucleus39.9
SuperiorCervicalGanglion40.4
TemporalLobe32.8
Testis813.65
TestisGermCell382.85
TestisIntersitial471.65
TestisLeydigCell330.6
TestisSeminiferousTubule255.2
Thalamus59.9
Thymus74.45
Thyroid69.4
Tongue40.3
Tonsil59.05
Trachea40.5
TrigeminalGanglion36.05
Uterus28.85
UterusCorpus30.9
WholeBlood52.75
Wholebrain66.95
colon199.05
pineal_day88.72
pineal_night68.56
retina117.8
small_intestine330.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P64010
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.35 ± 0.29
Basal Forebrain8.35 ± 0.1
Basal Part of Pons8.51 ± 0.13
Cerebellar Cortex8.48 ± 0.18
Cerebellar Nuclei8.54 ± 0.18
Claustrum8.45 ± 0.25
Epithalamus8.55 ± 0.13
Frontal Lobe8.62 ± 0.24
Globus Pallidus8.75 ± 0.21
Hypothalamus8.53 ± 0.19
Insula8.58 ± 0.17
Limbic Lobe8.48 ± 0.24
Mesencephalon8.53 ± 0.24
Myelencephalon8.49 ± 0.24
Occipital Lobe8.26 ± 0.18
Parietal Lobe8.54 ± 0.17
Pontine Tegmentum8.57 ± 0.26
Striatum8.59 ± 0.2
Subthalamus8.68 ± 0.3
Temporal Lobe8.54 ± 0.21
Thalamus8.61 ± 0.26
White Matter8.86 ± 0.09
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mtch2CBCerebellum100
100
Mtch2CTXCerebral cortex41.16
34.34
Mtch2HIPHippocampal region72.57
100
Mtch2HPFHippocampal formation69.17
94.2
Mtch2HYHypothalamus9.82
8.77
Mtch2LSXLateral septal complex3.36
2.8
Mtch2MBMidbrain25.78
26.92
Mtch2MYMedulla41.06
56.82
Mtch2OLFOlfactory bulb38.57
41.25
Mtch2PPons33.3
42.29
Mtch2PALPallidum9.25
9.44
Mtch2RHPRetrohippocampal region65.52
61.47
Mtch2sAMYStriatum-like amygdalar nuclei15.36
11.53
Mtch2STRStriatum5.35
4.38
Mtch2STRdStriatum dorsal region4.45
3.99
Mtch2STRvStriatum ventral region4.26
3.08
Mtch2THThalamus32
31.54
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MTCH2_HUMAN_131 16 131 146 SAATLITHPFHVITLR PRIDE
MTCH2_HUMAN_46 21 46 66 QVCQLPGLFSYAQHIASIDGR PRIDE
MTCH2_HUMAN_68 9 68 76 GLFTGLTPR PRIDE
MTCH2_HUMAN_77 13 77 89 LCSGVLGTVVHGK PRIDE
MTCH2_HUMAN_90 21 90 110 VLQHYQESDKGEELGPGNVQK PRIDE
PAp00002285 15 112 126 EVSSSFDHVIKETTR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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