AutismKB 2.0

Annotation Detail for NAT6


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Basic Information Top
Gene Symbol:NAT6 ( FUS-2,FUS2 )
Gene Full Name: N-acetyltransferase 6 (GCN5-related)
Band: 3p21.31
Quick LinksEntrez ID:24142; OMIM: 607073; Uniprot ID:NAT6_HUMAN; ENSEMBL ID: ENSG00000186792,ENSG00000243477; HGNC ID: 30252
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210874_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.4
Adipocyte5.75
AdrenalCortex6.15
Adrenalgland4.9
Amygdala6.25
Appendix6.1
AtrioventricularNode4.4
BDCA4+_DentriticCells6.65
Bonemarrow5.85
BronchialEpithelialCells5.8
CD105+_Endothelial5.8
CD14+_Monocytes6.3
CD19+_BCells(neg._sel.)6.35
CD33+_Myeloid6.9
CD34+7.5
CD4+_Tcells6.45
CD56+_NKCells7
CD71+_EarlyErythroid5.45
CD8+_Tcells5.8
CardiacMyocytes7.6
Caudatenucleus5.25
Cerebellum4.7
CerebellumPeduncles6.6
CiliaryGanglion4.05
CingulateCortex6
Colorectaladenocarcinoma6.4
DorsalRootGanglion4.4
FetalThyroid5.7
Fetalbrain5.7
Fetalliver5
Fetallung4.9
GlobusPallidus4.25
Heart7.95
Hypothalamus6.3
Kidney4.75
Leukemia_chronicMyelogenousK-5625.3
Leukemia_promyelocytic-HL-605.05
Leukemialymphoblastic(MOLT-4)5.05
Liver8.55
Lung6.55
Lymphnode5.05
Lymphoma_burkitts(Daudi)7.45
Lymphoma_burkitts(Raji)8.35
MedullaOblongata5.45
OccipitalLobe5.2
OlfactoryBulb4.6
Ovary3.85
Pancreas4.7
PancreaticIslet6.25
ParietalLobe6.15
Pituitary6.85
Placenta5.85
Pons5.5
PrefrontalCortex7.15
Prostate6.95
Salivarygland4.55
SkeletalMuscle6.95
Skin4.4
SmoothMuscle6.35
Spinalcord6.25
SubthalamicNucleus5.2
SuperiorCervicalGanglion6.5
TemporalLobe5.3
Testis14.7
TestisGermCell8.25
TestisIntersitial4.9
TestisLeydigCell5.95
TestisSeminiferousTubule5.05
Thalamus5.85
Thymus4.7
Thyroid7.5
Tongue5.65
Tonsil5.7
Trachea4.95
TrigeminalGanglion5.7
Uterus4.9
UterusCorpus5.2
WholeBlood6.5
Wholebrain5.2
colon5.9
pineal_day7.28
pineal_night7.1
retina7.075
small_intestine5.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9657_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.23 ± 0.75
Basal Forebrain2.14 ± 0.45
Basal Part of Pons2.09 ± 0.43
Cerebellar Cortex2.31 ± 0.56
Cerebellar Nuclei2.28 ± 0.74
Claustrum2.52 ± 0.91
Epithalamus1.75 ± 0.7
Frontal Lobe2.1 ± 0.71
Globus Pallidus1.99 ± 0.66
Hypothalamus2.09 ± 0.83
Insula1.84 ± 0.63
Limbic Lobe2.18 ± 0.62
Mesencephalon2.06 ± 0.79
Myelencephalon2.09 ± 0.62
Occipital Lobe2.03 ± 0.76
Parietal Lobe2.18 ± 0.71
Pontine Tegmentum2.08 ± 0.79
Striatum1.79 ± 0.81
Subthalamus1.96 ± 0.74
Temporal Lobe2.08 ± 0.69
Thalamus2.03 ± 0.65
White Matter1.47 ± 0.69
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nat6CBCerebellum40.65
32.09
Nat6CTXCerebral cortex49.25
34.06
Nat6HIPHippocampal region46.47
30.2
Nat6HPFHippocampal formation50.54
35.43
Nat6HYHypothalamus52.48
34.92
Nat6LSXLateral septal complex30.86
16.77
Nat6MBMidbrain30.87
21.87
Nat6MYMedulla48.14
40.74
Nat6OLFOlfactory bulb65.87
49.51
Nat6PPons42.92
33.9
Nat6PALPallidum33.34
23.82
Nat6RHPRetrohippocampal region52.84
38.78
Nat6sAMYStriatum-like amygdalar nuclei50.82
32.94
Nat6STRStriatum26.48
15.13
Nat6STRdStriatum dorsal region19.77
11.05
Nat6STRvStriatum ventral region37.31
19.48
Nat6THThalamus34.05
21.81
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00096808 18 90 107 RPELLDACADLINDQWPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018