AutismKB 2.0

Annotation Detail for TFIP11


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Basic Information Top
Gene Symbol:TFIP11 ( FLJ22086,NTR1,Spp382,TIP39,bK445C9.6,hNtr1 )
Gene Full Name: tuftelin interacting protein 11
Band: 22q12.1
Quick LinksEntrez ID:24144; OMIM: 612747; Uniprot ID:TFP11_HUMAN; ENSEMBL ID: ENSG00000100109; HGNC ID: 17165
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst4 / 6231964
fetus43 / 56401276
neonate6 / 31097192
infant3 / 23620127
juvenile7 / 55556125
adult104 / 193912153
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor3 / 3436687
chondrosarcoma10 / 82823120
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor21 / 26384579
glioma5 / 10688346
head and neck tumor12 / 13630288
kidney tumor10 / 68959145
leukemia9 / 9584293
liver tumor9 / 9635993
lung tumor2 / 10312719
lymphoma4 / 7175555
non-neoplasia6 / 9725061
normal206 / 336030761
ovarian tumor6 / 7668278
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor16 / 124949128
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites5 / 40015124
bladder1 / 2975733
blood11 / 12347889
bone0 / 716550 
bone marrow5 / 48801102
brain80 / 110098972
cervix3 / 4817162
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine15 / 23447263
kidney20 / 21177794
larynx0 / 241450 
liver14 / 20774367
lung14 / 33697441
lymph0 / 442700 
lymph node4 / 9161043
mammary gland9 / 15327158
mouth12 / 67052178
muscle1 / 1077159
nerve1 / 1576863
ovary10 / 10205197
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta20 / 28082571
prostate4 / 18934521
salivary gland0 / 201550 
skin24 / 210574113
spleen6 / 53952111
stomach3 / 9661931
testis52 / 330442157
thymus4 / 8113149
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus18 / 23287877
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202750_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts33.05
Adipocyte24.45
AdrenalCortex25.05
Adrenalgland20.25
Amygdala25.3
Appendix23.35
AtrioventricularNode18.3
BDCA4+_DentriticCells67
Bonemarrow24.75
BronchialEpithelialCells24.3
CD105+_Endothelial91.05
CD14+_Monocytes32.45
CD19+_BCells(neg._sel.)35.45
CD33+_Myeloid54
CD34+49.95
CD4+_Tcells35.15
CD56+_NKCells75.05
CD71+_EarlyErythroid41.2
CD8+_Tcells25.85
CardiacMyocytes32.2
Caudatenucleus21.1
Cerebellum19.75
CerebellumPeduncles27.6
CiliaryGanglion16.95
CingulateCortex27.15
Colorectaladenocarcinoma27.95
DorsalRootGanglion18.45
FetalThyroid23.85
Fetalbrain24.6
Fetalliver21
Fetallung20.55
GlobusPallidus17.8
Heart31.6
Hypothalamus26.1
Kidney19.65
Leukemia_chronicMyelogenousK-56222.3
Leukemia_promyelocytic-HL-6021.25
Leukemialymphoblastic(MOLT-4)19.95
Liver31.95
Lung28.65
Lymphnode21.2
Lymphoma_burkitts(Daudi)38.6
Lymphoma_burkitts(Raji)34.25
MedullaOblongata21.2
OccipitalLobe22.05
OlfactoryBulb19.35
Ovary16.15
Pancreas19.4
PancreaticIslet30.75
ParietalLobe25.35
Pituitary28.65
Placenta26.7
Pons21.4
PrefrontalCortex30.75
Prostate28.3
Salivarygland19.5
SkeletalMuscle35.25
Skin18.5
SmoothMuscle29.65
Spinalcord26.15
SubthalamicNucleus23
SuperiorCervicalGanglion27
TemporalLobe20.75
Testis63.1
TestisGermCell38.3
TestisIntersitial36.95
TestisLeydigCell29.4
TestisSeminiferousTubule24.25
Thalamus24.7
Thymus29.75
Thyroid31.15
Tongue22.65
Tonsil25.15
Trachea20.25
TrigeminalGanglion23.7
Uterus18.8
UterusCorpus21.75
WholeBlood38.85
Wholebrain21
colon23.2
pineal_day31.6
pineal_night30.16
retina29.475
small_intestine22.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14891_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.06 ± 0.7
Basal Forebrain3.85 ± 0.55
Basal Part of Pons4.44 ± 0.41
Cerebellar Cortex4.48 ± 0.46
Cerebellar Nuclei4.1 ± 0.84
Claustrum3.87 ± 0.76
Epithalamus4.38 ± 0.61
Frontal Lobe4.47 ± 0.51
Globus Pallidus4.12 ± 0.44
Hypothalamus4.22 ± 0.55
Insula4.52 ± 0.35
Limbic Lobe4.1 ± 0.49
Mesencephalon4.42 ± 0.57
Myelencephalon4.24 ± 0.56
Occipital Lobe3.96 ± 0.5
Parietal Lobe4.2 ± 0.56
Pontine Tegmentum4.21 ± 0.55
Striatum3.81 ± 0.63
Subthalamus4.41 ± 0.2
Temporal Lobe4.45 ± 0.47
Thalamus4.36 ± 0.51
White Matter4.07 ± 0.73
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tfip11CBCerebellum47.21
69.12
Tfip11CTXCerebral cortex80.96
67.51
Tfip11HIPHippocampal region77.37
100
Tfip11HPFHippocampal formation73.02
95.44
Tfip11HYHypothalamus11.26
10.11
Tfip11LSXLateral septal complex7.83
5.58
Tfip11MBMidbrain24.86
24.37
Tfip11MYMedulla36.46
41.37
Tfip11OLFOlfactory bulb59.28
52.57
Tfip11PPons24.2
28.04
Tfip11PALPallidum19.9
19.5
Tfip11RHPRetrohippocampal region62.53
57.76
Tfip11sAMYStriatum-like amygdalar nuclei31.58
25.34
Tfip11STRStriatum36.37
27.87
Tfip11STRdStriatum dorsal region40.88
31.81
Tfip11STRvStriatum ventral region32.9
23.34
Tfip11THThalamus26.22
26.54
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00063121 14 781 794 AEEHNIVFMPVIGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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