Annotation Detail for PANX1
Basic Information Top
| Gene Symbol: | PANX1 ( MGC21309,MRS1,PX1,UNQ2529 ) |
|---|---|
| Gene Full Name: | pannexin 1 |
| Band: | 11q21 |
| Quick Links | Entrez ID:24145; OMIM: 608420; Uniprot ID:PANX1_HUMAN; ENSEMBL ID: ENSG00000110218; HGNC ID: 8599 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.591976
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 28 / 564012 | 49 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 47 / 1939121 | 24 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 |  |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 6 / 82823 | 72 | |
| colorectal tumor | 1 / 114246 | 8 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 12 / 263845 | 45 | |
| glioma | 10 / 106883 | 93 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 4 / 95842 | 41 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 84 / 3360307 | 24 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 2 / 29757 | 67 | |
| blood | 0 / 123478 | 0 | |
| bone | 6 / 71655 | 83 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 24 / 1100989 | 21 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 4 / 149255 | 26 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 4 / 215722 | 18 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 2 / 211054 | 9 | |
| heart | 0 / 89626 | 0 | |
| intestine | 5 / 234472 | 21 | |
| kidney | 3 / 211777 | 14 | |
| larynx | 0 / 24145 | 0 | |
| liver | 5 / 207743 | 24 | |
| lung | 4 / 336974 | 11 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 4 / 91610 | 43 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 13 / 214812 | 60 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 5 / 280825 | 17 | |
| prostate | 6 / 189345 | 31 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 0 / 96619 | 0 | |
| testis | 13 / 330442 | 39 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 6 / 232878 | 25 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 204715_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 9.15 | |
| Adipocyte | 4.4 | |
| AdrenalCortex | 4.7 | |
| Adrenalgland | 3.7 | |
| Amygdala | 4.6 | |
| Appendix | 4.45 | |
| AtrioventricularNode | 3.4 | |
| BDCA4+_DentriticCells | 7.95 | |
| Bonemarrow | 4.35 | |
| BronchialEpithelialCells | 23.3 | |
| CD105+_Endothelial | 4.45 | |
| CD14+_Monocytes | 4.9 | |
| CD19+_BCells(neg._sel.) | 6.3 | |
| CD33+_Myeloid | 8.6 | |
| CD34+ | 5.75 | |
| CD4+_Tcells | 5.1 | |
| CD56+_NKCells | 6.6 | |
| CD71+_EarlyErythroid | 4.1 | |
| CD8+_Tcells | 4.4 | |
| CardiacMyocytes | 6.5 | |
| Caudatenucleus | 3.85 | |
| Cerebellum | 3.55 | |
| CerebellumPeduncles | 5 | |
| CiliaryGanglion | 3.4 | |
| CingulateCortex | 4.5 | |
| Colorectaladenocarcinoma | 4.3 | |
| DorsalRootGanglion | 3.6 | |
| FetalThyroid | 4.25 | |
| Fetalbrain | 4.25 | |
| Fetalliver | 3.75 | |
| Fetallung | 4.4 | |
| GlobusPallidus | 3.2 | |
| Heart | 5.7 | |
| Hypothalamus | 5 | |
| Kidney | 3.55 | |
| Leukemia_chronicMyelogenousK-562 | 3.9 | |
| Leukemia_promyelocytic-HL-60 | 3.85 | |
| Leukemialymphoblastic(MOLT-4) | 3.5 | |
| Liver | 5.8 | |
| Lung | 4.75 | |
| Lymphnode | 3.65 | |
| Lymphoma_burkitts(Daudi) | 5.6 | |
| Lymphoma_burkitts(Raji) | 6.3 | |
| MedullaOblongata | 3.8 | |
| OccipitalLobe | 3.95 | |
| OlfactoryBulb | 3.5 | |
| Ovary | 3.05 | |
| Pancreas | 3.6 | |
| PancreaticIslet | 4.75 | |
| ParietalLobe | 5.7 | |
| Pituitary | 5.2 | |
| Placenta | 4.6 | |
| Pons | 4.2 | |
| PrefrontalCortex | 5.55 | |
| Prostate | 5.05 | |
| Salivarygland | 3.55 | |
| SkeletalMuscle | 5.4 | |
| Skin | 3.75 | |
| SmoothMuscle | 11.7 | |
| Spinalcord | 4.55 | |
| SubthalamicNucleus | 4.05 | |
| SuperiorCervicalGanglion | 4.95 | |
| TemporalLobe | 4.05 | |
| Testis | 3.7 | |
| TestisGermCell | 5.05 | |
| TestisIntersitial | 3.7 | |
| TestisLeydigCell | 4.35 | |
| TestisSeminiferousTubule | 3.85 | |
| Thalamus | 4.5 | |
| Thymus | 3.5 | |
| Thyroid | 5.5 | |
| Tongue | 4.3 | |
| Tonsil | 4.25 | |
| Trachea | 3.7 | |
| TrigeminalGanglion | 4.4 | |
| Uterus | 3.85 | |
| UterusCorpus | 4.1 | |
| WholeBlood | 5.55 | |
| Wholebrain | 3.8 | |
| colon | 4.45 | |
| pineal_day | 5.38 | |
| pineal_night | 5.4 | |
| retina | 5.45 | |
| small_intestine | 4.25 | |
- Probe name: A_23_P47155
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.54 ± 0.33 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 7.41 ± 0.17 | |
| Basal Part of Pons | 7.17 ± 0.35 | |
| Cerebellar Cortex | 7.03 ± 0.28 | |
| Cerebellar Nuclei | 6.86 ± 0.4 | |
| Claustrum | 7.79 ± 0.33 | |
| Epithalamus | 6.93 ± 0.3 | |
| Frontal Lobe | 7.22 ± 0.38 | |
| Globus Pallidus | 6.58 ± 0.46 | |
| Hypothalamus | 7.53 ± 0.36 | |
| Insula | 7.29 ± 0.23 | |
| Limbic Lobe | 7.26 ± 0.38 | |
| Mesencephalon | 7.23 ± 0.47 | |
| Myelencephalon | 7.16 ± 0.44 | |
| Occipital Lobe | 6.99 ± 0.4 | |
| Parietal Lobe | 7.29 ± 0.44 | |
| Pontine Tegmentum | 7.15 ± 0.4 | |
| Striatum | 7.19 ± 0.46 | |
| Subthalamus | 7.27 ± 0.17 | |
| Temporal Lobe | 7.37 ± 0.3 | |
| Thalamus | 7.15 ± 0.34 | |
| White Matter | 5.68 ± 0.45 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Panx1 | CB | Cerebellum | 15.06 | |
| 19.59 | | |||
| Panx1 | CTX | Cerebral cortex | 14.86 | |
| 10.66 | | |||
| Panx1 | HIP | Hippocampal region | 14.16 | |
| 15.31 | | |||
| Panx1 | HPF | Hippocampal formation | 11.64 | |
| 11.68 | | |||
| Panx1 | HY | Hypothalamus | 7.3 | |
| 6.56 | | |||
| Panx1 | LSX | Lateral septal complex | 8.77 | |
| 6.98 | | |||
| Panx1 | MB | Midbrain | 6.82 | |
| 7.39 | | |||
| Panx1 | MY | Medulla | 8.94 | |
| 11.34 | | |||
| Panx1 | OLF | Olfactory bulb | 22.05 | |
| 19.33 | | |||
| Panx1 | P | Pons | 9.84 | |
| 14.52 | | |||
| Panx1 | PAL | Pallidum | 7.42 | |
| 7.98 | | |||
| Panx1 | RHP | Retrohippocampal region | 9.56 | |
| 8.53 | | |||
| Panx1 | sAMY | Striatum-like amygdalar nuclei | 3.19 | |
| 3.29 | | |||
| Panx1 | STR | Striatum | 5.15 | |
| 4.82 | | |||
| Panx1 | STRd | Striatum dorsal region | 3.8 | |
| 4.05 | | |||
| Panx1 | STRv | Striatum ventral region | 9.61 | |
| 7.22 | | |||
| Panx1 | TH | Thalamus | 5.13 | |
| 5.66 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PANX1_HUMAN_349 | 25 | 349 | 373 | VLENIKSSGQGIDPMLLLTNLGMIK | PRIDE |
| PAp00042480 | 22 | 322 | 343 | SEGYNDLSLYNLFLEENISEVK | Peptide Atlas |