AutismKB 2.0

Annotation Detail for ABL1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ABL1 ( ABL,JTK7,bcr/abl,c-ABL,p150,v-abl )
Gene Full Name: c-abl oncogene 1, non-receptor tyrosine kinase
Band: 9q34.12
Quick LinksEntrez ID:25; OMIM: 189980; Uniprot ID:ABL1_HUMAN; ENSEMBL ID: ENSG00000097007; HGNC ID: 76
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst8 / 62319128
fetus27 / 56401247
neonate2 / 3109764
infant1 / 2362042
juvenile2 / 5555635
adult120 / 193912161
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma7 / 8282384
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor12 / 26384545
glioma7 / 10688365
head and neck tumor11 / 13630280
kidney tumor8 / 68959116
leukemia6 / 9584262
liver tumor3 / 9635931
lung tumor18 / 103127174
lymphoma2 / 7175527
non-neoplasia5 / 9725051
normal179 / 336030753
ovarian tumor9 / 76682117
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor33 / 124949264
soft tissue/muscle tissue tumor24 / 125191191
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood2 / 12347816
bone5 / 7165569
bone marrow2 / 4880140
brain58 / 110098952
cervix5 / 48171103
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue20 / 21572292
esophagus0 / 202090 
eye17 / 21105480
heart6 / 8962666
intestine13 / 23447255
kidney13 / 21177761
larynx2 / 2414582
liver7 / 20774333
lung24 / 33697471
lymph2 / 4427045
lymph node5 / 9161054
mammary gland8 / 15327152
mouth6 / 6705289
muscle20 / 107715185
nerve0 / 157680 
ovary12 / 102051117
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta3 / 28082510
prostate13 / 18934568
salivary gland0 / 201550 
skin39 / 210574185
spleen3 / 5395255
stomach0 / 966190 
testis20 / 33044260
thymus1 / 8113112
thyroid3 / 4747363
tonsil1 / 1699958
trachea3 / 5241357
umbilical cord2 / 13680146
uterus25 / 232878107
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202123_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts102.05
Adipocyte43.7
AdrenalCortex11.8
Adrenalgland21.7
Amygdala16.95
Appendix10.4
AtrioventricularNode4.3
BDCA4+_DentriticCells28.6
Bonemarrow11.85
BronchialEpithelialCells15
CD105+_Endothelial31.9
CD14+_Monocytes10.5
CD19+_BCells(neg._sel.)21.8
CD33+_Myeloid13.65
CD34+41.85
CD4+_Tcells14.75
CD56+_NKCells31.95
CD71+_EarlyErythroid8.75
CD8+_Tcells22.1
CardiacMyocytes71.75
Caudatenucleus12.45
Cerebellum8.45
CerebellumPeduncles7.25
CiliaryGanglion5.95
CingulateCortex12.8
Colorectaladenocarcinoma16.4
DorsalRootGanglion3.75
FetalThyroid67.7
Fetalbrain19.5
Fetalliver6.2
Fetallung44.05
GlobusPallidus5.25
Heart35.15
Hypothalamus41.85
Kidney21.95
Leukemia_chronicMyelogenousK-562194
Leukemia_promyelocytic-HL-607.1
Leukemialymphoblastic(MOLT-4)27.2
Liver13.85
Lung100.45
Lymphnode12.6
Lymphoma_burkitts(Daudi)10.5
Lymphoma_burkitts(Raji)30.3
MedullaOblongata10.95
OccipitalLobe11.7
OlfactoryBulb29.2
Ovary15.25
Pancreas8.35
PancreaticIslet11.6
ParietalLobe9.95
Pituitary19.85
Placenta43.4
Pons6.4
PrefrontalCortex47.75
Prostate106.4
Salivarygland4.5
SkeletalMuscle6.6
Skin5.3
SmoothMuscle238.4
Spinalcord35.55
SubthalamicNucleus6.3
SuperiorCervicalGanglion8.2
TemporalLobe6.55
Testis20.45
TestisGermCell20.65
TestisIntersitial6.85
TestisLeydigCell5.65
TestisSeminiferousTubule11.05
Thalamus10.55
Thymus31.5
Thyroid135.15
Tongue10.3
Tonsil9
Trachea20.05
TrigeminalGanglion8
Uterus192.95
UterusCorpus35.25
WholeBlood8
Wholebrain33
colon71.5
pineal_day57.04
pineal_night28.06
retina99.15
small_intestine38.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P282416
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.69 ± 0.93
Basal Forebrain3.03 ± 0.54
Basal Part of Pons3.16 ± 0.35
Cerebellar Cortex3.73 ± 0.49
Cerebellar Nuclei3.62 ± 0.67
Claustrum3.52 ± 0.56
Epithalamus3.51 ± 0.7
Frontal Lobe3.34 ± 0.64
Globus Pallidus4.02 ± 0.89
Hypothalamus3.24 ± 0.72
Insula3.69 ± 0.43
Limbic Lobe3.61 ± 0.54
Mesencephalon3.79 ± 0.75
Myelencephalon3.52 ± 0.56
Occipital Lobe3.79 ± 0.57
Parietal Lobe3.42 ± 0.53
Pontine Tegmentum3.56 ± 0.65
Striatum3.66 ± 0.65
Subthalamus3.65 ± 0.28
Temporal Lobe3.51 ± 0.64
Thalamus3.5 ± 0.6
White Matter4.53 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Abl1CBCerebellum46.68
59.8
Abl1CTXCerebral cortex47.38
32.54
Abl1HIPHippocampal region36.53
41.76
Abl1HPFHippocampal formation41.08
39.1
Abl1HYHypothalamus19.41
14.76
Abl1LSXLateral septal complex28.66
19.12
Abl1MBMidbrain31.26
25.44
Abl1MYMedulla29.32
23.11
Abl1OLFOlfactory bulb54.07
44.9
Abl1PPons28.15
23.35
Abl1PALPallidum25.85
20.31
Abl1RHPRetrohippocampal region49.06
35.34
Abl1sAMYStriatum-like amygdalar nuclei29.75
20.85
Abl1STRStriatum37.5
27.6
Abl1STRdStriatum dorsal region43.25
33.02
Abl1STRvStriatum ventral region25.51
16.86
Abl1THThalamus28.45
22.75
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00063314 22 910 931 AGGKPSQSPSQEAAGEAVLGAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved