AutismKB 2.0

Annotation Detail for FUCA1


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Basic Information Top
Gene Symbol:FUCA1 ( FUCA )
Gene Full Name: fucosidase, alpha-L- 1, tissue
Band: 1p36.11
Quick LinksEntrez ID:2517; OMIM: 612280; Uniprot ID:FUCO_HUMAN; ENSEMBL ID: ENSG00000179163; HGNC ID: 4006
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus27 / 56401247
neonate794 / 3109725533
infant1 / 2362042
juvenile17 / 55556305
adult186 / 193912195
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor18 / 94178191
cervical tumor6 / 34366174
chondrosarcoma11 / 82823132
colorectal tumor5 / 11424643
esophageal tumor6 / 17290347
gastrointestinal tumor7 / 11936958
germ cell tumor44 / 263845166
glioma23 / 106883215
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia22 / 95842229
liver tumor9 / 9635993
lung tumor4 / 10312738
lymphoma8 / 71755111
non-neoplasia46 / 97250473
normal1932 / 3360307574
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS17 / 125680135
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites1 / 4001524
bladder4 / 29757134
blood887 / 1234787183
bone8 / 71655111
bone marrow2 / 4880140
brain97 / 110098988
cervix8 / 48171166
connective tissue51 / 149255341
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus6 / 20209296
eye7 / 21105433
heart8 / 8962689
intestine85 / 234472362
kidney45 / 211777212
larynx1 / 2414541
liver17 / 20774381
lung29 / 33697486
lymph1 / 4427022
lymph node9 / 9161098
mammary gland28 / 153271182
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary6 / 10205158
pancreas5 / 21481223
parathyroid10 / 20539486
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta30 / 280825106
prostate17 / 18934589
salivary gland1 / 2015549
skin13 / 21057461
spleen38 / 53952704
stomach21 / 96619217
testis52 / 330442157
thymus26 / 81131320
thyroid3 / 4747363
tonsil2 / 16999117
trachea12 / 52413228
umbilical cord0 / 136800 
uterus20 / 23287885
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202838_at
Cell line Expression level Expression bar
721_B_lymphoblasts26.7
Adipocyte6.7
AdrenalCortex6.7
Adrenalgland71.8
Amygdala11.25
Appendix4.95
AtrioventricularNode3.75
BDCA4+_DentriticCells60.8
Bonemarrow41.05
BronchialEpithelialCells65.9
CD105+_Endothelial134.5
CD14+_Monocytes367.95
CD19+_BCells(neg._sel.)10.3
CD33+_Myeloid276.95
CD34+23.85
CD4+_Tcells9
CD56+_NKCells27.5
CD71+_EarlyErythroid4.65
CD8+_Tcells7.1
CardiacMyocytes8.05
Caudatenucleus6.35
Cerebellum4.35
CerebellumPeduncles5.5
CiliaryGanglion4.55
CingulateCortex5.05
Colorectaladenocarcinoma84.8
DorsalRootGanglion3.8
FetalThyroid188.05
Fetalbrain7.15
Fetalliver59.35
Fetallung31.3
GlobusPallidus3.9
Heart12.4
Hypothalamus19.95
Kidney76.4
Leukemia_chronicMyelogenousK-56218.35
Leukemia_promyelocytic-HL-6014.7
Leukemialymphoblastic(MOLT-4)5.4
Liver129.35
Lung241.4
Lymphnode277.05
Lymphoma_burkitts(Daudi)16
Lymphoma_burkitts(Raji)6.85
MedullaOblongata4.3
OccipitalLobe5.9
OlfactoryBulb9.5
Ovary4.15
Pancreas39.35
PancreaticIslet186.5
ParietalLobe5.8
Pituitary74.15
Placenta332.65
Pons4.4
PrefrontalCortex7.5
Prostate124.65
Salivarygland39.1
SkeletalMuscle4.7
Skin5.05
SmoothMuscle6.7
Spinalcord16.8
SubthalamicNucleus8.65
SuperiorCervicalGanglion4.5
TemporalLobe3.55
Testis114.85
TestisGermCell72
TestisIntersitial40.6
TestisLeydigCell43.2
TestisSeminiferousTubule31.85
Thalamus10.7
Thymus64.1
Thyroid302.3
Tongue6.45
Tonsil199.05
Trachea137.1
TrigeminalGanglion4.85
Uterus12.95
UterusCorpus6.55
WholeBlood40.45
Wholebrain16.3
colon144.2
pineal_day10.94
pineal_night10.24
retina25.45
small_intestine135.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9969_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.7 ± 0.69
Basal Forebrain3.17 ± 0.3
Basal Part of Pons3.42 ± 0.32
Cerebellar Cortex3.5 ± 0.55
Cerebellar Nuclei3.93 ± 0.55
Claustrum3.6 ± 0.6
Epithalamus3.58 ± 0.52
Frontal Lobe3.64 ± 0.56
Globus Pallidus3.5 ± 0.8
Hypothalamus3.72 ± 0.66
Insula3.63 ± 0.77
Limbic Lobe3.65 ± 0.52
Mesencephalon3.64 ± 0.57
Myelencephalon3.64 ± 0.59
Occipital Lobe3.49 ± 0.43
Parietal Lobe3.56 ± 0.55
Pontine Tegmentum3.75 ± 0.59
Striatum3.67 ± 0.56
Subthalamus3.4 ± 0.59
Temporal Lobe3.61 ± 0.59
Thalamus3.67 ± 0.56
White Matter3.42 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fuca1CBCerebellum19.27
33.99
Fuca1CTXCerebral cortex60.01
52.7
Fuca1HIPHippocampal region67.38
100
Fuca1HPFHippocampal formation61.34
86.64
Fuca1HYHypothalamus35.44
34.53
Fuca1LSXLateral septal complex14.78
11.29
Fuca1MBMidbrain25.74
29.18
Fuca1MYMedulla19.01
28.33
Fuca1OLFOlfactory bulb43
40.4
Fuca1PPons24.93
33.6
Fuca1PALPallidum44
46.56
Fuca1RHPRetrohippocampal region52.84
49.49
Fuca1sAMYStriatum-like amygdalar nuclei57.3
51.5
Fuca1STRStriatum28.13
22.64
Fuca1STRdStriatum dorsal region22.38
17.89
Fuca1STRvStriatum ventral region37.51
26.88
Fuca1THThalamus34.27
33
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
FUCO_HUMAN_113 17 113 129 FFHPEEWADLFQAAGAK PRIDE
FUCO_HUMAN_158 11 158 168 DLVGELGTALR PRIDE
PAp00092388 17 114 130 FFHPEEWADLFQAAGAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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