AutismKB 2.0

Annotation Detail for NEIL2


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Basic Information Top
Gene Symbol:NEIL2 ( FLJ31644,MGC2832,MGC4505,NEH2,NEI2 )
Gene Full Name: nei endonuclease VIII-like 2 (E. coli)
Band: 8p23.1
Quick LinksEntrez ID:252969; OMIM: 608933; Uniprot ID:NEIL2_HUMAN; ENSEMBL ID: ENSG00000154328; HGNC ID: 18956
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus20 / 56401235
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult47 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor9 / 26384534
glioma4 / 10688337
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia7 / 9584273
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal109 / 336030732
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor4 / 12494932
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder2 / 2975767
blood5 / 12347840
bone6 / 7165583
bone marrow3 / 4880161
brain50 / 110098945
cervix5 / 48171103
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus1 / 2020949
eye5 / 21105423
heart3 / 8962633
intestine4 / 23447217
kidney6 / 21177728
larynx0 / 241450 
liver2 / 2077439
lung7 / 33697420
lymph0 / 442700 
lymph node2 / 9161021
mammary gland4 / 15327126
mouth1 / 6705214
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate6 / 18934531
salivary gland0 / 201550 
skin7 / 21057433
spleen1 / 5395218
stomach0 / 966190 
testis7 / 33044221
thymus2 / 8113124
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular4 / 5178077
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P94128
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.34 ± 0.49
Basal Forebrain6.52 ± 0.36
Basal Part of Pons6.07 ± 0.24
Cerebellar Cortex6 ± 0.27
Cerebellar Nuclei6.44 ± 0.45
Claustrum6.82 ± 0.46
Epithalamus6.2 ± 0.27
Frontal Lobe6.23 ± 0.36
Globus Pallidus6.58 ± 0.35
Hypothalamus6.71 ± 0.27
Insula6.37 ± 0.27
Limbic Lobe6.49 ± 0.38
Mesencephalon6.32 ± 0.52
Myelencephalon6.29 ± 0.38
Occipital Lobe6.59 ± 0.33
Parietal Lobe6.35 ± 0.34
Pontine Tegmentum6.43 ± 0.42
Striatum6.19 ± 0.44
Subthalamus6.36 ± 0.1
Temporal Lobe6.35 ± 0.38
Thalamus6.03 ± 0.32
White Matter5.4 ± 0.1
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018