AutismKB 2.0

Annotation Detail for FNDC5


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Basic Information Top
Gene Symbol:FNDC5 ( FRCP2 )
Gene Full Name: fibronectin type III domain containing 5
Band: 1p35.1
Quick LinksEntrez ID:252995; OMIM: 611906; Uniprot ID:FNDC5_HUMAN; ENSEMBL ID: ENSG00000160097; HGNC ID: 20240
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus16 / 56401228
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult33 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma9 / 10688384
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal80 / 336030723
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain33 / 110098929
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye20 / 21105494
heart3 / 8962633
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung29 / 33697486
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle13 / 107715120
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate6 / 18934531
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_4787_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.21 ± 0.49
Basal Forebrain6.27 ± 0.27
Basal Part of Pons7.31 ± 0.28
Cerebellar Cortex7.42 ± 0.2
Cerebellar Nuclei7.52 ± 0.33
Claustrum5.76 ± 0.38
Epithalamus6.34 ± 0.35
Frontal Lobe6.78 ± 0.45
Globus Pallidus6.94 ± 0.36
Hypothalamus6.2 ± 0.21
Insula6.61 ± 0.52
Limbic Lobe6.74 ± 0.58
Mesencephalon6.67 ± 0.46
Myelencephalon6.85 ± 0.55
Occipital Lobe7.41 ± 0.41
Parietal Lobe7.1 ± 0.46
Pontine Tegmentum6.74 ± 0.53
Striatum6.13 ± 0.27
Subthalamus7.43 ± 0.15
Temporal Lobe6.82 ± 0.45
Thalamus7.44 ± 0.42
White Matter4.72 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fndc5CBCerebellum37.56
66.71
Fndc5CTXCerebral cortex27.28
22.95
Fndc5HIPHippocampal region28.75
47.73
Fndc5HPFHippocampal formation23.97
32.87
Fndc5HYHypothalamus16.61
17.13
Fndc5LSXLateral septal complex13.37
10.85
Fndc5MBMidbrain34.43
40.18
Fndc5MYMedulla46.04
61.85
Fndc5OLFOlfactory bulb29.22
30.49
Fndc5PPons36.46
45.88
Fndc5PALPallidum32.79
42.9
Fndc5RHPRetrohippocampal region17.5
16.24
Fndc5sAMYStriatum-like amygdalar nuclei9.63
10.17
Fndc5STRStriatum12.18
10.58
Fndc5STRdStriatum dorsal region11.6
9.96
Fndc5STRvStriatum ventral region15.74
12.99
Fndc5THThalamus42.49
47.35
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018