AutismKB 2.0

Annotation Detail for SERHL2


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Basic Information Top
Gene Symbol:SERHL2 ( MGC149508,MGC157667,MGC157668,dJ222E13.1 )
Gene Full Name: serine hydrolase-like 2
Band: 22q13.2
Quick LinksEntrez ID:253190; OMIM: NA; Uniprot ID:SEHL2_HUMAN; ENSEMBL ID: ENSG00000183569; HGNC ID: 29446
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217284_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.15
Adipocyte4.05
AdrenalCortex4.6
Adrenalgland3.55
Amygdala4.3
Appendix4.2
AtrioventricularNode3.5
BDCA4+_DentriticCells4.6
Bonemarrow4.4
BronchialEpithelialCells4.05
CD105+_Endothelial4.2
CD14+_Monocytes4.45
CD19+_BCells(neg._sel.)4.4
CD33+_Myeloid5.35
CD34+5.3
CD4+_Tcells4.55
CD56+_NKCells4.95
CD71+_EarlyErythroid3.9
CD8+_Tcells4
CardiacMyocytes6.15
Caudatenucleus3.75
Cerebellum3.4
CerebellumPeduncles4.8
CiliaryGanglion2.95
CingulateCortex4.3
Colorectaladenocarcinoma4.2
DorsalRootGanglion3.4
FetalThyroid4.1
Fetalbrain4.5
Fetalliver3.65
Fetallung3.4
GlobusPallidus3.1
Heart5.6
Hypothalamus4.5
Kidney3.4
Leukemia_chronicMyelogenousK-5623.8
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)4.6
Liver5.5
Lung4.6
Lymphnode3.6
Lymphoma_burkitts(Daudi)5.5
Lymphoma_burkitts(Raji)5.95
MedullaOblongata3.75
OccipitalLobe3.75
OlfactoryBulb3.3
Ovary2.9
Pancreas3.35
PancreaticIslet4.4
ParietalLobe4.45
Pituitary4.9
Placenta4.25
Pons4.05
PrefrontalCortex5.2
Prostate4.95
Salivarygland3.35
SkeletalMuscle4.8
Skin3.9
SmoothMuscle4.7
Spinalcord4.45
SubthalamicNucleus3.8
SuperiorCervicalGanglion5.25
TemporalLobe3.85
Testis3.6
TestisGermCell3.5
TestisIntersitial3.6
TestisLeydigCell4.15
TestisSeminiferousTubule4.05
Thalamus4.25
Thymus3.25
Thyroid5.25
Tongue4.3
Tonsil4.1
Trachea3.5
TrigeminalGanglion4.15
Uterus3.45
UterusCorpus3.7
WholeBlood4.6
Wholebrain3.45
colon4.15
pineal_day5.18
pineal_night5.12
retina5.1
small_intestine3.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P120953
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.84 ± 0.29
Basal Forebrain6.42 ± 0.23
Basal Part of Pons6.23 ± 0.31
Cerebellar Cortex5.64 ± 0.2
Cerebellar Nuclei6.27 ± 0.39
Claustrum5.8 ± 0.41
Epithalamus6.28 ± 0.44
Frontal Lobe6.09 ± 0.37
Globus Pallidus6.74 ± 0.24
Hypothalamus6.49 ± 0.35
Insula5.95 ± 0.34
Limbic Lobe5.84 ± 0.53
Mesencephalon6.09 ± 0.41
Myelencephalon6.03 ± 0.38
Occipital Lobe5.66 ± 0.37
Parietal Lobe5.9 ± 0.35
Pontine Tegmentum5.94 ± 0.42
Striatum6.11 ± 0.36
Subthalamus6.74 ± 0.34
Temporal Lobe5.87 ± 0.36
Thalamus5.96 ± 0.36
White Matter7.77 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
SerhlRHPRetrohippocampal region0.38
0.28
SerhlsAMYStriatum-like amygdalar nuclei0.4
0.66
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018