AutismKB 2.0

Annotation Detail for IFI6


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Basic Information Top
Gene Symbol:IFI6 ( 6-16,FAM14C,G1P3,IFI-6-16,IFI616 )
Gene Full Name: interferon, alpha-inducible protein 6
Band: 1p35.3
Quick LinksEntrez ID:2537; OMIM: 147572; Uniprot ID:IFI6_HUMAN; ENSEMBL ID: ENSG00000126709; HGNC ID: 4054
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst15 / 62319240
fetus7 / 56401212
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult106 / 193912154
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor22 / 94178233
cervical tumor3 / 3436687
chondrosarcoma6 / 8282372
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor27 / 263845102
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal113 / 336030733
ovarian tumor2 / 7668226
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor10 / 12494980
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood9 / 12347872
bone7 / 7165597
bone marrow0 / 488010 
brain26 / 110098923
cervix3 / 4817162
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye4 / 21105418
heart1 / 8962611
intestine7 / 23447229
kidney4 / 21177718
larynx0 / 241450 
liver7 / 20774333
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland22 / 153271143
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta38 / 280825135
prostate8 / 18934542
salivary gland2 / 2015599
skin17 / 21057480
spleen4 / 5395274
stomach11 / 96619113
testis15 / 33044245
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus16 / 23287868
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204415_at
Cell line Expression level Expression bar
721_B_lymphoblasts26
Adipocyte21.6
AdrenalCortex23.15
Adrenalgland35.25
Amygdala21.5
Appendix19.8
AtrioventricularNode14.45
BDCA4+_DentriticCells22.95
Bonemarrow19.05
BronchialEpithelialCells12.35
CD105+_Endothelial19.9
CD14+_Monocytes68
CD19+_BCells(neg._sel.)18.55
CD33+_Myeloid38.05
CD34+22.65
CD4+_Tcells21.9
CD56+_NKCells22.85
CD71+_EarlyErythroid6.4
CD8+_Tcells19.85
CardiacMyocytes21.65
Caudatenucleus42.45
Cerebellum18.15
CerebellumPeduncles22.5
CiliaryGanglion13.65
CingulateCortex20.4
Colorectaladenocarcinoma19.25
DorsalRootGanglion15.7
FetalThyroid19.45
Fetalbrain22.15
Fetalliver10.8
Fetallung17.05
GlobusPallidus14.4
Heart41.7
Hypothalamus96.5
Kidney15.85
Leukemia_chronicMyelogenousK-56212.35
Leukemia_promyelocytic-HL-6015.55
Leukemialymphoblastic(MOLT-4)18.55
Liver25.75
Lung487.75
Lymphnode47.65
Lymphoma_burkitts(Daudi)69.65
Lymphoma_burkitts(Raji)27.35
MedullaOblongata18.65
OccipitalLobe18.1
OlfactoryBulb18.95
Ovary13
Pancreas29.1
PancreaticIslet20.15
ParietalLobe20.8
Pituitary41.5
Placenta555.3
Pons18.95
PrefrontalCortex25.6
Prostate296.8
Salivarygland15.65
SkeletalMuscle21.65
Skin13.3
SmoothMuscle28.85
Spinalcord98.2
SubthalamicNucleus17.95
SuperiorCervicalGanglion21.9
TemporalLobe17.8
Testis17.45
TestisGermCell32.35
TestisIntersitial14.85
TestisLeydigCell19.3
TestisSeminiferousTubule17.95
Thalamus22
Thymus120.45
Thyroid237.1
Tongue18.9
Tonsil61.5
Trachea35.6
TrigeminalGanglion21.65
Uterus33.4
UterusCorpus17.15
WholeBlood71.45
Wholebrain113.75
colon19.85
pineal_day36.48
pineal_night29.08
retina23.9
small_intestine19.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10153_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.48 ± 0.45
Basal Forebrain5.3 ± 0.36
Basal Part of Pons5.49 ± 0.3
Cerebellar Cortex5.54 ± 0.48
Cerebellar Nuclei5.18 ± 0.25
Claustrum6.1 ± 0.26
Epithalamus5.84 ± 0.42
Frontal Lobe5.89 ± 0.48
Globus Pallidus5.83 ± 0.55
Hypothalamus6.04 ± 0.53
Insula5.66 ± 0.36
Limbic Lobe5.5 ± 0.65
Mesencephalon5.59 ± 0.5
Myelencephalon5.72 ± 0.62
Occipital Lobe5.19 ± 0.54
Parietal Lobe5.5 ± 0.47
Pontine Tegmentum5.72 ± 0.61
Striatum5.25 ± 0.43
Subthalamus5.91 ± 0.45
Temporal Lobe5.65 ± 0.46
Thalamus5.51 ± 0.47
White Matter4.93 ± 0.34
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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