AutismKB 2.0

Annotation Detail for WDR27


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Basic Information Top
Gene Symbol:WDR27 ( MGC43690 )
Gene Full Name: WD repeat domain 27
Band: 6q27
Quick LinksEntrez ID:253769; OMIM: NA; Uniprot ID:WDR27_HUMAN; ENSEMBL ID: ENSG00000184465; HGNC ID: 21248
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst5 / 6231980
fetus37 / 56401265
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult30 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal83 / 336030724
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood0 / 1234780 
bone3 / 7165541
bone marrow2 / 4880140
brain14 / 110098912
cervix0 / 481710 
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye0 / 2110540 
heart3 / 8962633
intestine10 / 23447242
kidney4 / 21177718
larynx0 / 241450 
liver1 / 2077434
lung6 / 33697417
lymph0 / 442700 
lymph node10 / 91610109
mammary gland3 / 15327119
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta3 / 28082510
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis11 / 33044233
thymus5 / 8113161
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_323_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.7 ± 1.07
Basal Forebrain1.92 ± 0.56
Basal Part of Pons1.72 ± 0.42
Cerebellar Cortex2.18 ± 0.69
Cerebellar Nuclei2.24 ± 0.78
Claustrum2.56 ± 0.83
Epithalamus3.16 ± 0.75
Frontal Lobe2.02 ± 0.75
Globus Pallidus2.31 ± 0.49
Hypothalamus2.28 ± 0.5
Insula1.56 ± 0.52
Limbic Lobe2.08 ± 0.65
Mesencephalon2.28 ± 0.78
Myelencephalon2.22 ± 0.71
Occipital Lobe2.32 ± 0.55
Parietal Lobe2.07 ± 0.74
Pontine Tegmentum2.13 ± 0.66
Striatum2.67 ± 0.74
Subthalamus2.43 ± 0.16
Temporal Lobe1.99 ± 0.73
Thalamus2.01 ± 0.68
White Matter2.55 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wdr27CBCerebellum0.39
0.96
Wdr27CTXCerebral cortex0.59
0.9
Wdr27HIPHippocampal region0.63
0.93
Wdr27HPFHippocampal formation0.48
0.76
Wdr27HYHypothalamus0.16
0.19
Wdr27LSXLateral septal complex0
0
Wdr27MBMidbrain0.26
0.59
Wdr27MYMedulla0.45
0.62
Wdr27OLFOlfactory bulb1.28
1.53
Wdr27PPons0.33
0.52
Wdr27PALPallidum0.21
0.27
Wdr27RHPRetrohippocampal region0.19
0.29
Wdr27sAMYStriatum-like amygdalar nuclei0.75
0.97
Wdr27STRStriatum0.38
0.37
Wdr27STRdStriatum dorsal region0.33
0.33
Wdr27STRvStriatum ventral region0.63
0.48
Wdr27THThalamus0.19
0.31
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018