AutismKB 2.0

Annotation Detail for FBXO33


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Basic Information Top
Gene Symbol:FBXO33 ( BMND12,Fbx33,c14_5247 )
Gene Full Name: F-box protein 33
Band: 14q21.1
Quick LinksEntrez ID:254170; OMIM: 609103; Uniprot ID:FBX33_HUMAN; ENSEMBL ID: ENSG00000165355; HGNC ID: 19833
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus8 / 56401214
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult32 / 193912116
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal56 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood0 / 1234780 
bone2 / 7165527
bone marrow2 / 4880140
brain16 / 110098914
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye5 / 21105423
heart3 / 8962633
intestine1 / 2344724
kidney5 / 21177723
larynx0 / 241450 
liver1 / 2077434
lung10 / 33697429
lymph1 / 4427022
lymph node1 / 9161010
mammary gland3 / 15327119
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta2 / 2808257
prostate6 / 18934531
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis8 / 33044224
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P41021
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.08 ± 0.59
Basal Forebrain6.29 ± 0.19
Basal Part of Pons6.53 ± 0.41
Cerebellar Cortex6.54 ± 0.18
Cerebellar Nuclei6.26 ± 0.5
Claustrum6.13 ± 0.42
Epithalamus6.52 ± 0.36
Frontal Lobe6.67 ± 0.43
Globus Pallidus5.8 ± 0.36
Hypothalamus6.33 ± 0.64
Insula6.5 ± 0.31
Limbic Lobe6.58 ± 0.46
Mesencephalon6.35 ± 0.44
Myelencephalon6.5 ± 0.48
Occipital Lobe6.95 ± 0.35
Parietal Lobe6.86 ± 0.45
Pontine Tegmentum6.58 ± 0.49
Striatum6.13 ± 0.44
Subthalamus6.67 ± 0.08
Temporal Lobe6.55 ± 0.43
Thalamus6.64 ± 0.33
White Matter5.54 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fbxo33CBCerebellum18.55
26.39
Fbxo33CTXCerebral cortex28.01
22.3
Fbxo33HIPHippocampal region18.97
20.18
Fbxo33HPFHippocampal formation16.33
15.62
Fbxo33HYHypothalamus3.89
3.56
Fbxo33LSXLateral septal complex5.1
3.75
Fbxo33MBMidbrain9.88
10.75
Fbxo33MYMedulla20.24
24.6
Fbxo33OLFOlfactory bulb12.67
10.66
Fbxo33PPons14.75
18.01
Fbxo33PALPallidum6.8
6.45
Fbxo33RHPRetrohippocampal region12.16
9.52
Fbxo33sAMYStriatum-like amygdalar nuclei5.19
3.59
Fbxo33STRStriatum2.84
2.11
Fbxo33STRdStriatum dorsal region2.06
1.47
Fbxo33STRvStriatum ventral region3.72
2.99
Fbxo33THThalamus7.62
7.25
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018