AutismKB 2.0

Annotation Detail for MCM9


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Basic Information Top
Gene Symbol:MCM9 ( C6orf61,FLJ13942,FLJ20170,FLJ56845,MCMDC1,MGC35304,dJ329L24.1,dJ329L24.3 )
Gene Full Name: minichromosome maintenance complex component 9
Band: 6q22.31
Quick LinksEntrez ID:254394; OMIM: 610098; Uniprot ID:MCM9_HUMAN; ENSEMBL ID: ENSG00000111877; HGNC ID: 21484
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal54 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow3 / 4880161
brain9 / 11009898
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver3 / 20774314
lung1 / 3369742
lymph0 / 442700 
lymph node11 / 91610120
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach4 / 9661941
testis12 / 33044236
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219673_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.4
Adipocyte4.95
AdrenalCortex5.5
Adrenalgland4.35
Amygdala5.15
Appendix5.95
AtrioventricularNode4.6
BDCA4+_DentriticCells8.5
Bonemarrow5.25
BronchialEpithelialCells5
CD105+_Endothelial5.25
CD14+_Monocytes5.9
CD19+_BCells(neg._sel.)27.85
CD33+_Myeloid9.4
CD34+19.9
CD4+_Tcells6.15
CD56+_NKCells16.9
CD71+_EarlyErythroid4.85
CD8+_Tcells5.05
CardiacMyocytes6.8
Caudatenucleus4.55
Cerebellum4.1
CerebellumPeduncles5.85
CiliaryGanglion4.2
CingulateCortex5.3
Colorectaladenocarcinoma5.05
DorsalRootGanglion4.95
FetalThyroid5
Fetalbrain4.9
Fetalliver4.5
Fetallung4.1
GlobusPallidus3.9
Heart7.4
Hypothalamus5.5
Kidney4.3
Leukemia_chronicMyelogenousK-5624.6
Leukemia_promyelocytic-HL-604.5
Leukemialymphoblastic(MOLT-4)4.05
Liver6.9
Lung5.55
Lymphnode4.4
Lymphoma_burkitts(Daudi)6.6
Lymphoma_burkitts(Raji)7.45
MedullaOblongata4.55
OccipitalLobe4.5
OlfactoryBulb4.05
Ovary3.8
Pancreas4.1
PancreaticIslet5.5
ParietalLobe5.5
Pituitary5.95
Placenta5.3
Pons4.9
PrefrontalCortex6.15
Prostate5.9
Salivarygland4.2
SkeletalMuscle6.3
Skin4.25
SmoothMuscle5.7
Spinalcord5.45
SubthalamicNucleus4.8
SuperiorCervicalGanglion9.25
TemporalLobe4.65
Testis4.4
TestisGermCell4.15
TestisIntersitial4.3
TestisLeydigCell5.3
TestisSeminiferousTubule4.4
Thalamus5.2
Thymus4
Thyroid6.5
Tongue5.2
Tonsil5
Trachea4.3
TrigeminalGanglion5.55
Uterus4.1
UterusCorpus4.65
WholeBlood5.65
Wholebrain4.05
colon5.1
pineal_day6.42
pineal_night6.34
retina6.225
small_intestine4.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8382_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.99 ± 1.16
Basal Forebrain2.55 ± 0.31
Basal Part of Pons2.29 ± 0.45
Cerebellar Cortex2.67 ± 0.86
Cerebellar Nuclei3 ± 0.65
Claustrum3.41 ± 0.94
Epithalamus2.72 ± 0.62
Frontal Lobe2.5 ± 0.78
Globus Pallidus3.63 ± 0.86
Hypothalamus2.51 ± 0.7
Insula2.37 ± 0.81
Limbic Lobe2.56 ± 0.83
Mesencephalon2.82 ± 0.81
Myelencephalon2.62 ± 0.72
Occipital Lobe2.68 ± 0.68
Parietal Lobe2.51 ± 0.83
Pontine Tegmentum2.73 ± 0.84
Striatum2.98 ± 0.86
Subthalamus2.88 ± 0.39
Temporal Lobe2.48 ± 0.74
Thalamus2.58 ± 0.68
White Matter3.74 ± 0.98
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mcmdc1CBCerebellum1.8
1.77
Mcmdc1CTXCerebral cortex1.11
1.28
Mcmdc1HIPHippocampal region1
0.75
Mcmdc1HPFHippocampal formation0.88
0.66
Mcmdc1HYHypothalamus0.3
0.38
Mcmdc1LSXLateral septal complex0.12
0.09
Mcmdc1MBMidbrain1.42
1.32
Mcmdc1MYMedulla4.62
4.72
Mcmdc1OLFOlfactory bulb3.11
3.62
Mcmdc1PPons2.37
2.51
Mcmdc1PALPallidum0.27
0.57
Mcmdc1RHPRetrohippocampal region0.63
0.57
Mcmdc1sAMYStriatum-like amygdalar nuclei0.54
0.57
Mcmdc1STRStriatum0.2
0.15
Mcmdc1STRdStriatum dorsal region0.19
0.13
Mcmdc1STRvStriatum ventral region0.1
0.05
Mcmdc1THThalamus0.53
0.37
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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