AutismKB 2.0

Annotation Detail for TMEM86B


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Basic Information Top
Gene Symbol:TMEM86B ( MGC30208 )
Gene Full Name: transmembrane protein 86B
Band: 19q13.42
Quick LinksEntrez ID:255043; OMIM: NA; Uniprot ID:TM86B_HUMAN; ENSEMBL ID: ENSG00000180089; HGNC ID: 28448
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult10 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal27 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone4 / 7165555
bone marrow0 / 488010 
brain4 / 11009893
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus3 / 8113136
thyroid0 / 474730 
tonsil3 / 16999176
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P121956
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.02 ± 0.58
Basal Forebrain8.32 ± 0.57
Basal Part of Pons7.66 ± 0.23
Cerebellar Cortex7.57 ± 0.22
Cerebellar Nuclei8.55 ± 0.32
Claustrum8.45 ± 0.62
Epithalamus7.07 ± 0.51
Frontal Lobe8.02 ± 0.57
Globus Pallidus8.74 ± 0.37
Hypothalamus7.51 ± 0.83
Insula7.86 ± 0.64
Limbic Lobe8.02 ± 0.64
Mesencephalon8.23 ± 0.52
Myelencephalon8.15 ± 0.72
Occipital Lobe8.3 ± 0.67
Parietal Lobe8.17 ± 0.56
Pontine Tegmentum8.17 ± 0.61
Striatum8.73 ± 0.51
Subthalamus8.24 ± 0.65
Temporal Lobe7.9 ± 0.64
Thalamus8.49 ± 0.6
White Matter7.55 ± 0.1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem86bCBCerebellum3.59
3.67
Tmem86bCTXCerebral cortex10.66
6.66
Tmem86bHIPHippocampal region14.48
13.27
Tmem86bHPFHippocampal formation11.46
9.33
Tmem86bHYHypothalamus2.61
1.58
Tmem86bLSXLateral septal complex2.45
2.09
Tmem86bMBMidbrain5.41
4.44
Tmem86bMYMedulla8.1
7.31
Tmem86bOLFOlfactory bulb10.78
7.35
Tmem86bPPons7.01
5.54
Tmem86bPALPallidum3.85
2.58
Tmem86bRHPRetrohippocampal region7.2
4.69
Tmem86bsAMYStriatum-like amygdalar nuclei2.65
1.49
Tmem86bSTRStriatum4.77
3.42
Tmem86bSTRdStriatum dorsal region4.86
3.72
Tmem86bSTRvStriatum ventral region6.65
4.01
Tmem86bTHThalamus2.55
2.19
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018