AutismKB 2.0

Annotation Detail for PAN3


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Basic Information Top
Gene Symbol:PAN3 ( - )
Gene Full Name: PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
Band: 13q12.2
Quick LinksEntrez ID:255967; OMIM: NA; Uniprot ID:PAN3_HUMAN; ENSEMBL ID: ENSG00000152520; HGNC ID: 29991
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus17 / 56401230
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult49 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor9 / 26384534
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia3 / 9725030
normal84 / 336030724
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain15 / 110098913
cervix0 / 481710 
connective tissue3 / 14925520
ear1 / 1621261
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine5 / 23447221
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung11 / 33697432
lymph0 / 442700 
lymph node10 / 91610109
mammary gland9 / 15327158
mouth2 / 6705229
muscle4 / 10771537
nerve2 / 15768126
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta14 / 28082549
prostate4 / 18934521
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach4 / 9661941
testis10 / 33044230
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P385938
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.94 ± 0.59
Basal Forebrain3.91 ± 0.44
Basal Part of Pons4.02 ± 0.51
Cerebellar Cortex4.64 ± 0.33
Cerebellar Nuclei4.18 ± 1.11
Claustrum3.44 ± 0.77
Epithalamus4.64 ± 0.48
Frontal Lobe3.92 ± 0.65
Globus Pallidus4.1 ± 0.58
Hypothalamus3.83 ± 0.8
Insula4.07 ± 0.63
Limbic Lobe3.93 ± 0.55
Mesencephalon4.17 ± 0.56
Myelencephalon3.91 ± 0.63
Occipital Lobe3.99 ± 0.5
Parietal Lobe3.89 ± 0.59
Pontine Tegmentum4.03 ± 0.59
Striatum3.85 ± 0.56
Subthalamus3.85 ± 0.31
Temporal Lobe4.05 ± 0.52
Thalamus3.85 ± 0.62
White Matter5.03 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pan3CBCerebellum42.31
46.86
Pan3CTXCerebral cortex32.49
23.22
Pan3HIPHippocampal region34.73
52.34
Pan3HPFHippocampal formation34.88
42.59
Pan3HYHypothalamus23.06
19.61
Pan3LSXLateral septal complex13.2
9.57
Pan3MBMidbrain11.37
9.95
Pan3MYMedulla21.65
22
Pan3OLFOlfactory bulb71.95
56.15
Pan3PPons19.01
19.98
Pan3PALPallidum19.35
15.48
Pan3RHPRetrohippocampal region35.51
28.33
Pan3sAMYStriatum-like amygdalar nuclei37.94
27.47
Pan3STRStriatum23.42
16.57
Pan3STRdStriatum dorsal region15.99
11.17
Pan3STRvStriatum ventral region43.55
28.99
Pan3THThalamus15.53
14.49
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018