AutismKB 2.0

Annotation Detail for KANK3


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Basic Information Top
Gene Symbol:KANK3 ( ANKRD47,FLJ46061 )
Gene Full Name: KN motif and ankyrin repeat domains 3
Band: 19p13.2
Quick LinksEntrez ID:256949; OMIM: NA; Uniprot ID:KANK3_HUMAN; ENSEMBL ID: ENSG00000186994; HGNC ID: 24796
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst74 / 623191187
fetus56 / 56401299
neonate4 / 31097128
infant3 / 23620127
juvenile2 / 5555635
adult183 / 193912194
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor3 / 3436687
chondrosarcoma0 / 828230 
colorectal tumor13 / 114246113
esophageal tumor1 / 1729057
gastrointestinal tumor11 / 11936992
germ cell tumor8 / 26384530
glioma6 / 10688356
head and neck tumor2 / 13630214
kidney tumor3 / 6895943
leukemia13 / 95842135
liver tumor2 / 9635920
lung tumor5 / 10312748
lymphoma8 / 71755111
non-neoplasia1 / 9725010
normal491 / 3360307146
ovarian tumor6 / 7668278
pancreatic tumor28 / 104616267
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer24 / 102680233
retinoblastoma2 / 4635643
skin tumor7 / 12494956
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood12 / 12347897
bone8 / 71655111
bone marrow15 / 48801307
brain75 / 110098968
cervix4 / 4817183
connective tissue1 / 1492556
ear3 / 16212185
embryonic tissue152 / 215722704
esophagus1 / 2020949
eye17 / 21105480
heart25 / 89626278
intestine26 / 234472110
kidney13 / 21177761
larynx0 / 241450 
liver15 / 20774372
lung12 / 33697435
lymph6 / 44270135
lymph node5 / 9161054
mammary gland9 / 15327158
mouth2 / 6705229
muscle31 / 107715287
nerve0 / 157680 
ovary7 / 10205168
pancreas41 / 214812190
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta10 / 28082535
prostate31 / 189345163
salivary gland2 / 2015599
skin8 / 21057437
spleen2 / 5395237
stomach23 / 96619238
testis6 / 33044218
thymus2 / 8113124
thyroid1 / 4747321
tonsil6 / 16999352
trachea0 / 524130 
umbilical cord4 / 13680292
uterus5 / 23287821
vascular8 / 51780154
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213715_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts18.75
Adipocyte16.3
AdrenalCortex19.4
Adrenalgland14.75
Amygdala14.95
Appendix18.2
AtrioventricularNode18.05
BDCA4+_DentriticCells16.45
Bonemarrow17.65
BronchialEpithelialCells15.85
CD105+_Endothelial16.75
CD14+_Monocytes17.55
CD19+_BCells(neg._sel.)17
CD33+_Myeloid17.95
CD34+20.05
CD4+_Tcells16.8
CD56+_NKCells19.55
CD71+_EarlyErythroid18.1
CD8+_Tcells15.45
CardiacMyocytes23.55
Caudatenucleus18.2
Cerebellum13.7
CerebellumPeduncles19.9
CiliaryGanglion18.65
CingulateCortex18.85
Colorectaladenocarcinoma15.05
DorsalRootGanglion15.35
FetalThyroid20.3
Fetalbrain17
Fetalliver14.6
Fetallung18.7
GlobusPallidus12.85
Heart48.5
Hypothalamus17.85
Kidney14.75
Leukemia_chronicMyelogenousK-56215.3
Leukemia_promyelocytic-HL-6014.85
Leukemialymphoblastic(MOLT-4)13.05
Liver23.5
Lung73
Lymphnode14.4
Lymphoma_burkitts(Daudi)22.05
Lymphoma_burkitts(Raji)24.6
MedullaOblongata15.3
OccipitalLobe15.1
OlfactoryBulb13.35
Ovary14.35
Pancreas14.7
PancreaticIslet17.95
ParietalLobe18.4
Pituitary19.35
Placenta26.25
Pons27.65
PrefrontalCortex20.25
Prostate18.9
Salivarygland13.75
SkeletalMuscle22.15
Skin15.7
SmoothMuscle18.65
Spinalcord19.35
SubthalamicNucleus15.75
SuperiorCervicalGanglion23.8
TemporalLobe15.55
Testis14.05
TestisGermCell13.3
TestisIntersitial13.9
TestisLeydigCell17.9
TestisSeminiferousTubule17.9
Thalamus18.2
Thymus12.55
Thyroid20.5
Tongue19.5
Tonsil16.55
Trachea13.9
TrigeminalGanglion19.6
Uterus13.6
UterusCorpus17.15
WholeBlood17.3
Wholebrain13.25
colon10.8
pineal_day19.24
pineal_night19.66
retina20.275
small_intestine15.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P7693
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.68 ± 0.93
Basal Forebrain2.36 ± 0.43
Basal Part of Pons2.35 ± 0.84
Cerebellar Cortex2.29 ± 0.8
Cerebellar Nuclei2.72 ± 0.92
Claustrum3.25 ± 1.03
Epithalamus1.97 ± 0.68
Frontal Lobe2.24 ± 0.74
Globus Pallidus3.2 ± 0.75
Hypothalamus2.25 ± 0.76
Insula2.43 ± 0.5
Limbic Lobe2.43 ± 0.7
Mesencephalon2.53 ± 0.99
Myelencephalon2.52 ± 0.72
Occipital Lobe2.61 ± 0.84
Parietal Lobe2.46 ± 0.78
Pontine Tegmentum2.38 ± 0.69
Striatum2.63 ± 0.8
Subthalamus2.48 ± 0.91
Temporal Lobe2.36 ± 0.77
Thalamus2.39 ± 0.71
White Matter2.48 ± 0.49
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ankrd47CBCerebellum1.64
2.07
Ankrd47CTXCerebral cortex2.46
2.48
Ankrd47HIPHippocampal region1.87
1.64
Ankrd47HPFHippocampal formation1.73
1.38
Ankrd47HYHypothalamus0.58
0.39
Ankrd47LSXLateral septal complex0.23
0.16
Ankrd47MBMidbrain1.42
1.42
Ankrd47MYMedulla4.77
5
Ankrd47OLFOlfactory bulb28.86
25.72
Ankrd47PPons1.87
2.07
Ankrd47PALPallidum1.54
1.08
Ankrd47RHPRetrohippocampal region1.36
0.92
Ankrd47sAMYStriatum-like amygdalar nuclei1.99
1.57
Ankrd47STRStriatum2.93
1.98
Ankrd47STRdStriatum dorsal region3.23
2.23
Ankrd47STRvStriatum ventral region3.52
2.09
Ankrd47THThalamus1.56
1.26
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
KANK3_HUMAN_384 11 384 394 EAAEEAAAGAR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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