AutismKB 2.0

Annotation Detail for NEGR1


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Basic Information Top
Gene Symbol:NEGR1 ( DMML2433,IGLON4,KILON,MGC46680,Ntra )
Gene Full Name: neuronal growth regulator 1
Band: 1p31.1
Quick LinksEntrez ID:257194; OMIM: 613173; Uniprot ID:NEGR1_HUMAN; ENSEMBL ID: ENSG00000172260; HGNC ID: 17302
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor9 / 26384534
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal104 / 336030730
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor15 / 125191119
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain77 / 110098969
cervix0 / 481710 
connective tissue16 / 149255107
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine0 / 2344720 
kidney9 / 21177742
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis4 / 33044212
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea8 / 52413152
umbilical cord0 / 136800 
uterus5 / 23287821
vascular4 / 5178077
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11195_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.54 ± 0.4
Basal Forebrain7.95 ± 0.37
Basal Part of Pons7.16 ± 0.34
Cerebellar Cortex8.43 ± 0.14
Cerebellar Nuclei6.84 ± 0.53
Claustrum7.19 ± 0.57
Epithalamus7.96 ± 0.37
Frontal Lobe7.77 ± 0.48
Globus Pallidus6.28 ± 0.5
Hypothalamus8.13 ± 0.62
Insula8.16 ± 0.34
Limbic Lobe8.03 ± 0.62
Mesencephalon7.7 ± 0.73
Myelencephalon7.79 ± 0.71
Occipital Lobe8.57 ± 0.55
Parietal Lobe7.84 ± 0.52
Pontine Tegmentum7.95 ± 0.63
Striatum6.76 ± 0.77
Subthalamus7.2 ± 0.5
Temporal Lobe8.05 ± 0.4
Thalamus7.1 ± 0.65
White Matter6.8 ± 0.58
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Negr1CBCerebellum56.83
40.36
Negr1CTXCerebral cortex81.71
70.31
Negr1HIPHippocampal region66.8
54.28
Negr1HPFHippocampal formation68.39
61.63
Negr1HYHypothalamus44.8
35.86
Negr1LSXLateral septal complex8.34
5.73
Negr1MBMidbrain34.33
29.25
Negr1MYMedulla53.02
51.49
Negr1OLFOlfactory bulb100
100
Negr1PPons51.95
49.53
Negr1PALPallidum39.59
39.74
Negr1RHPRetrohippocampal region70.9
70.17
Negr1sAMYStriatum-like amygdalar nuclei74.41
62.41
Negr1STRStriatum36.28
28.58
Negr1STRdStriatum dorsal region24.1
18.08
Negr1STRvStriatum ventral region71.75
54.21
Negr1THThalamus24.71
20.12
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00065630 28 100 127 DYSLQIQNVDVTDDGPYTCSVQTQHTPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018