AutismKB 2.0

Annotation Detail for SHPRH


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Basic Information Top
Gene Symbol:SHPRH ( FLJ27258,FLJ37625,FLJ45012,FLJ90837,KIAA2023,MGC134886,bA545I5.2 )
Gene Full Name: SNF2 histone linker PHD RING helicase
Band: 6q24.3
Quick LinksEntrez ID:257218; OMIM: 608048; Uniprot ID:SHPRH_HUMAN; ENSEMBL ID: ENSG00000146414; HGNC ID: 19336
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus16 / 56401228
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult28 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal57 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain17 / 110098915
cervix3 / 4817162
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus1 / 2020949
eye5 / 21105423
heart3 / 8962633
intestine4 / 23447217
kidney4 / 21177718
larynx1 / 2414541
liver4 / 20774319
lung3 / 3369748
lymph0 / 442700 
lymph node2 / 9161021
mammary gland1 / 1532716
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach3 / 9661931
testis3 / 3304429
thymus4 / 8113149
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P153576
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.09 ± 0.38
Basal Forebrain8.03 ± 0.13
Basal Part of Pons7.86 ± 0.22
Cerebellar Cortex8.41 ± 0.16
Cerebellar Nuclei7.89 ± 0.2
Claustrum8.08 ± 0.24
Epithalamus8.13 ± 0.51
Frontal Lobe7.89 ± 0.25
Globus Pallidus7.97 ± 0.29
Hypothalamus7.86 ± 0.2
Insula8.01 ± 0.31
Limbic Lobe8.12 ± 0.36
Mesencephalon8.08 ± 0.27
Myelencephalon8.02 ± 0.26
Occipital Lobe8.43 ± 0.32
Parietal Lobe8.07 ± 0.27
Pontine Tegmentum8.03 ± 0.34
Striatum8.11 ± 0.32
Subthalamus7.96 ± 0.09
Temporal Lobe8.03 ± 0.23
Thalamus8.02 ± 0.25
White Matter8.82 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
ShprhCBCerebellum66.24
91.51
ShprhLSXLateral septal complex8.39
5.42
ShprhMYMedulla38.79
35.97
ShprhSTRdStriatum dorsal region30.28
21.07
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018