AutismKB 2.0

Annotation Detail for PRPF40B


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Basic Information Top
Gene Symbol:PRPF40B ( HYPC )
Gene Full Name: PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
Band: 12q13.12
Quick LinksEntrez ID:25766; OMIM: NA; Uniprot ID:PR40B_HUMAN; ENSEMBL ID: ENSG00000110844; HGNC ID: 25031
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult51 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor7 / 26384526
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal60 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer8 / 10268077
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain12 / 110098910
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye9 / 21105442
heart2 / 8962622
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver2 / 2077439
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth0 / 670520 
muscle3 / 10771527
nerve2 / 15768126
ovary7 / 10205168
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta5 / 28082517
prostate8 / 18934542
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis6 / 33044218
thymus1 / 8113112
thyroid5 / 47473105
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_83_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.14 ± 0.52
Basal Forebrain4.94 ± 0.4
Basal Part of Pons4.82 ± 0.48
Cerebellar Cortex4.62 ± 0.4
Cerebellar Nuclei4.66 ± 0.58
Claustrum5.48 ± 0.64
Epithalamus4.63 ± 0.34
Frontal Lobe4.62 ± 0.49
Globus Pallidus5.41 ± 0.44
Hypothalamus4.66 ± 0.35
Insula4.6 ± 0.79
Limbic Lobe5.06 ± 0.47
Mesencephalon4.88 ± 0.56
Myelencephalon4.91 ± 0.51
Occipital Lobe5.21 ± 0.58
Parietal Lobe4.93 ± 0.5
Pontine Tegmentum4.77 ± 0.51
Striatum4.9 ± 0.59
Subthalamus4.08 ± 0.28
Temporal Lobe4.83 ± 0.45
Thalamus4.68 ± 0.6
White Matter5.19 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Prpf40bCBCerebellum1.24
1.63
Prpf40bCTXCerebral cortex1.49
1.28
Prpf40bHIPHippocampal region0.8
0.89
Prpf40bHPFHippocampal formation0.77
0.79
Prpf40bHYHypothalamus0.14
0.18
Prpf40bLSXLateral septal complex0.3
0.24
Prpf40bMBMidbrain1.01
1.1
Prpf40bMYMedulla3.9
4.74
Prpf40bOLFOlfactory bulb0.96
0.74
Prpf40bPPons0.66
0.81
Prpf40bPALPallidum0.35
0.3
Prpf40bRHPRetrohippocampal region0.63
0.59
Prpf40bsAMYStriatum-like amygdalar nuclei0.92
0.81
Prpf40bSTRStriatum0.4
0.33
Prpf40bSTRdStriatum dorsal region0.34
0.29
Prpf40bSTRvStriatum ventral region0.31
0.2
Prpf40bTHThalamus0.91
0.75
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00516784 12 286 297 VPSNASWEQAMK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018