AutismKB 2.0

Annotation Detail for SUN2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SUN2 ( KIAA0668,MGC133055,MGC133056,UNC84B )
Gene Full Name: Sad1 and UNC84 domain containing 2
Band: 22q13.1
Quick LinksEntrez ID:25777; OMIM: 613569; Uniprot ID:SUN2_HUMAN; ENSEMBL ID: ENSG00000100242; HGNC ID: 14210
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst3 / 6231948
fetus43 / 56401276
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult186 / 193912195
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma8 / 8282396
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor15 / 119369125
germ cell tumor10 / 26384537
glioma13 / 106883121
head and neck tumor5 / 13630236
kidney tumor7 / 68959101
leukemia18 / 95842187
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia14 / 97250143
normal338 / 3360307100
ovarian tumor2 / 7668226
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor5 / 12494940
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue5 / 13106381
adrenal gland2 / 3319760
ascites3 / 4001574
bladder3 / 29757100
blood19 / 123478153
bone11 / 71655153
bone marrow4 / 4880181
brain128 / 1100989116
cervix6 / 48171124
connective tissue13 / 14925587
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye18 / 21105485
heart2 / 8962622
intestine19 / 23447281
kidney16 / 21177775
larynx1 / 2414541
liver3 / 20774314
lung22 / 33697465
lymph0 / 442700 
lymph node17 / 91610185
mammary gland9 / 15327158
mouth3 / 6705244
muscle8 / 10771574
nerve2 / 15768126
ovary2 / 10205119
pancreas11 / 21481251
parathyroid2 / 2053997
pharynx8 / 41328193
pituitary gland0 / 165850 
placenta26 / 28082592
prostate6 / 18934531
salivary gland0 / 201550 
skin7 / 21057433
spleen10 / 53952185
stomach7 / 9661972
testis37 / 330442111
thymus16 / 81131197
thyroid4 / 4747384
tonsil0 / 169990 
trachea8 / 52413152
umbilical cord0 / 136800 
uterus23 / 23287898
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212144_at
Cell line Expression level Expression bar
721_B_lymphoblasts93.2
Adipocyte138.25
AdrenalCortex63.15
Adrenalgland66.7
Amygdala165.85
Appendix76.65
AtrioventricularNode55.2
BDCA4+_DentriticCells283
Bonemarrow146.55
BronchialEpithelialCells61.95
CD105+_Endothelial124.2
CD14+_Monocytes364.2
CD19+_BCells(neg._sel.)523.9
CD33+_Myeloid584.65
CD34+248.95
CD4+_Tcells841.5
CD56+_NKCells1536.1
CD71+_EarlyErythroid121.55
CD8+_Tcells820.3
CardiacMyocytes78.3
Caudatenucleus198.6
Cerebellum94.1
CerebellumPeduncles137.45
CiliaryGanglion44.95
CingulateCortex128.1
Colorectaladenocarcinoma66.6
DorsalRootGanglion82.3
FetalThyroid70.9
Fetalbrain92
Fetalliver67.5
Fetallung65.25
GlobusPallidus73.85
Heart149.25
Hypothalamus374.9
Kidney91.85
Leukemia_chronicMyelogenousK-56255.25
Leukemia_promyelocytic-HL-6053.45
Leukemialymphoblastic(MOLT-4)87.4
Liver144.55
Lung296.7
Lymphnode198.15
Lymphoma_burkitts(Daudi)75.05
Lymphoma_burkitts(Raji)81.95
MedullaOblongata213.6
OccipitalLobe120.4
OlfactoryBulb151.4
Ovary67.45
Pancreas61.8
PancreaticIslet123.15
ParietalLobe162.75
Pituitary90.55
Placenta143.1
Pons103.1
PrefrontalCortex302.55
Prostate224.4
Salivarygland65.85
SkeletalMuscle68.6
Skin48.1
SmoothMuscle83.7
Spinalcord256.2
SubthalamicNucleus82.8
SuperiorCervicalGanglion41.3
TemporalLobe75.25
Testis111.8
TestisGermCell94.55
TestisIntersitial48.7
TestisLeydigCell85.9
TestisSeminiferousTubule64.9
Thalamus319.65
Thymus223.8
Thyroid97.25
Tongue59.05
Tonsil117.15
Trachea90
TrigeminalGanglion70.85
Uterus156.8
UterusCorpus52.8
WholeBlood478.45
Wholebrain262.9
colon72.35
pineal_day57.6
pineal_night74.04
retina112.525
small_intestine60.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7279_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.35 ± 0.81
Basal Forebrain3.03 ± 0.95
Basal Part of Pons3.37 ± 0.86
Cerebellar Cortex3.25 ± 0.67
Cerebellar Nuclei3.41 ± 0.61
Claustrum3.16 ± 0.57
Epithalamus3.08 ± 0.76
Frontal Lobe3.23 ± 0.83
Globus Pallidus4.24 ± 0.35
Hypothalamus2.73 ± 0.65
Insula2.6 ± 0.92
Limbic Lobe3.19 ± 0.74
Mesencephalon3.24 ± 0.82
Myelencephalon3.21 ± 0.65
Occipital Lobe3.35 ± 0.7
Parietal Lobe3.13 ± 0.65
Pontine Tegmentum3.24 ± 0.69
Striatum3.6 ± 0.88
Subthalamus3.23 ± 0.91
Temporal Lobe3.19 ± 0.67
Thalamus3.24 ± 0.62
White Matter5.54 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Unc84bCBCerebellum22.1
37.61
Unc84bCTXCerebral cortex18.26
13.54
Unc84bHIPHippocampal region8.94
8.67
Unc84bHPFHippocampal formation9.82
9.22
Unc84bHYHypothalamus3.6
3.22
Unc84bLSXLateral septal complex4.65
4.47
Unc84bMBMidbrain9.47
10.56
Unc84bMYMedulla24.11
32.22
Unc84bOLFOlfactory bulb36.98
36.88
Unc84bPPons18.01
23.76
Unc84bPALPallidum6.54
6.25
Unc84bRHPRetrohippocampal region11.29
9.71
Unc84bsAMYStriatum-like amygdalar nuclei5.33
4.23
Unc84bSTRStriatum71.18
62.06
Unc84bSTRdStriatum dorsal region80.97
73.94
Unc84bSTRvStriatum ventral region56.21
45.08
Unc84bTHThalamus18.9
18.26
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00039833 17 451 467 DDVESQFPAWISQFLAR Peptide Atlas
Q504T5_HUMAN_412 19 412 430 RLEDQLAGLQQELAALALK PRIDE
Q504T5_HUMAN_570 19 570 588 TALLSLFGIPLWYHSQSPR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved