Annotation Detail for NGEF
Basic Information Top
| Gene Symbol: | NGEF ( ARHGEF27,EPHEXIN ) |
|---|---|
| Gene Full Name: | neuronal guanine nucleotide exchange factor |
| Band: | 2q37.1 |
| Quick Links | Entrez ID:25791; OMIM: 605991; Uniprot ID:NGEF_HUMAN; ENSEMBL ID: ENSG00000066248; HGNC ID: 7807 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.97316
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 23 / 564012 | 40 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 35 / 1939121 | 18 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 7 / 82823 | 84 |  |
| colorectal tumor | 1 / 114246 | 8 |  |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 1 / 263845 | 3 | |
| glioma | 4 / 106883 | 37 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 7 / 97250 | 71 | |
| normal | 90 / 3360307 | 26 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 2 / 102680 | 19 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 3 / 125191 | 23 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 10 / 33197 | 301 |  |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 10 / 71655 | 139 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 44 / 1100989 | 39 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 5 / 149255 | 33 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 10 / 211054 | 47 | |
| heart | 0 / 89626 | 0 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 7 / 211777 | 33 | |
| larynx | 0 / 24145 | 0 | |
| liver | 1 / 207743 | 4 | |
| lung | 1 / 336974 | 2 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 3 / 214812 | 13 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 5 / 189345 | 26 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 2 / 210574 | 9 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 2 / 330442 | 6 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_23_P102364
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 11.82 ± 0.84 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 12.21 ± 0.79 | |
| Basal Part of Pons | 13.17 ± 0.3 | |
| Cerebellar Cortex | 9.75 ± 0.45 | |
| Cerebellar Nuclei | 8.79 ± 0.97 | |
| Claustrum | 12.11 ± 1.26 | |
| Epithalamus | 11.51 ± 1.12 | |
| Frontal Lobe | 11.36 ± 0.72 | |
| Globus Pallidus | 8.48 ± 2.89 | |
| Hypothalamus | 11.15 ± 0.68 | |
| Insula | 11.29 ± 0.36 | |
| Limbic Lobe | 11 ± 1.19 | |
| Mesencephalon | 10.37 ± 1.11 | |
| Myelencephalon | 11.07 ± 1.14 | |
| Occipital Lobe | 11.26 ± 0.81 | |
| Parietal Lobe | 11.45 ± 0.86 | |
| Pontine Tegmentum | 10.68 ± 0.93 | |
| Striatum | 12.98 ± 0.64 | |
| Subthalamus | 9.09 ± 0.39 | |
| Temporal Lobe | 11.22 ± 0.79 | |
| Thalamus | 10.13 ± 0.88 | |
| White Matter | 8.76 ± 1.6 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Ngef | CB | Cerebellum | 18.35 | |
| 44.07 | | |||
| Ngef | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Ngef | HIP | Hippocampal region | 82.54 | |
| 100 | | |||
| Ngef | HPF | Hippocampal formation | 94.73 | |
| 100 | | |||
| Ngef | HY | Hypothalamus | 56.9 | |
| 55.04 | | |||
| Ngef | LSX | Lateral septal complex | 100 | |
| 100 | | |||
| Ngef | MB | Midbrain | 61.34 | |
| 70.6 | | |||
| Ngef | MY | Medulla | 28.99 | |
| 33.24 | | |||
| Ngef | OLF | Olfactory bulb | 98.52 | |
| 100 | | |||
| Ngef | P | Pons | 36.5 | |
| 41.49 | | |||
| Ngef | PAL | Pallidum | 66.29 | |
| 83.57 | | |||
| Ngef | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Ngef | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 100 | | |||
| Ngef | STR | Striatum | 100 | |
| 100 | | |||
| Ngef | STRd | Striatum dorsal region | 100 | |
| 100 | | |||
| Ngef | STRv | Striatum ventral region | 100 | |
| 100 | | |||
| Ngef | TH | Thalamus | 20.67 | |
| 21.38 | |