AutismKB 2.0

Annotation Detail for CIZ1


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Basic Information Top
Gene Symbol:CIZ1 ( LSFR1,NP94,ZNF356 )
Gene Full Name: CDKN1A interacting zinc finger protein 1
Band: 9q34.11
Quick LinksEntrez ID:25792; OMIM: 611420; Uniprot ID:CIZ1_HUMAN; ENSEMBL ID: ENSG00000148337; HGNC ID: 16744
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body12 / 70761169
blastocyst9 / 62319144
fetus51 / 56401290
neonate2 / 3109764
infant0 / 236200 
juvenile8 / 55556143
adult255 / 1939121131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor14 / 94178148
cervical tumor15 / 34366436
chondrosarcoma14 / 82823169
colorectal tumor29 / 114246253
esophageal tumor0 / 172900 
gastrointestinal tumor25 / 119369209
germ cell tumor38 / 263845144
glioma21 / 106883196
head and neck tumor27 / 136302198
kidney tumor15 / 68959217
leukemia16 / 95842166
liver tumor4 / 9635941
lung tumor27 / 103127261
lymphoma16 / 71755222
non-neoplasia3 / 9725030
normal328 / 336030797
ovarian tumor12 / 76682156
pancreatic tumor17 / 104616162
primitive neuroectodermal tumor of the CNS32 / 125680254
prostate cancer8 / 10268077
retinoblastoma11 / 46356237
skin tumor26 / 124949208
soft tissue/muscle tissue tumor22 / 125191175
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites17 / 40015424
bladder2 / 2975767
blood16 / 123478129
bone8 / 71655111
bone marrow0 / 488010 
brain114 / 1100989103
cervix16 / 48171332
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue29 / 215722134
esophagus0 / 202090 
eye29 / 211054137
heart11 / 89626122
intestine47 / 234472200
kidney24 / 211777113
larynx3 / 24145124
liver14 / 20774367
lung56 / 336974166
lymph14 / 44270316
lymph node6 / 9161065
mammary gland19 / 153271123
mouth2 / 6705229
muscle17 / 107715157
nerve1 / 1576863
ovary20 / 102051195
pancreas32 / 214812148
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta37 / 280825131
prostate19 / 189345100
salivary gland15 / 20155744
skin35 / 210574166
spleen5 / 5395292
stomach8 / 9661982
testis30 / 33044290
thymus13 / 81131160
thyroid9 / 47473189
tonsil2 / 16999117
trachea3 / 5241357
umbilical cord2 / 13680146
uterus35 / 232878150
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205516_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts165.3
Adipocyte81.85
AdrenalCortex50.7
Adrenalgland55.85
Amygdala75.1
Appendix47.15
AtrioventricularNode37.05
BDCA4+_DentriticCells165.55
Bonemarrow67.95
BronchialEpithelialCells68
CD105+_Endothelial126.55
CD14+_Monocytes152.2
CD19+_BCells(neg._sel.)112.25
CD33+_Myeloid87.85
CD34+214.95
CD4+_Tcells122.3
CD56+_NKCells166.15
CD71+_EarlyErythroid214.8
CD8+_Tcells110.8
CardiacMyocytes69.4
Caudatenucleus64.35
Cerebellum65.25
CerebellumPeduncles87
CiliaryGanglion33.85
CingulateCortex83.45
Colorectaladenocarcinoma222.05
DorsalRootGanglion35.85
FetalThyroid98.3
Fetalbrain133.95
Fetalliver44.2
Fetallung65.95
GlobusPallidus45.15
Heart144.2
Hypothalamus57.65
Kidney40.95
Leukemia_chronicMyelogenousK-562345.6
Leukemia_promyelocytic-HL-6065.4
Leukemialymphoblastic(MOLT-4)200.8
Liver62.2
Lung258.3
Lymphnode86.8
Lymphoma_burkitts(Daudi)191.1
Lymphoma_burkitts(Raji)136.15
MedullaOblongata90.65
OccipitalLobe64.2
OlfactoryBulb70.45
Ovary31.8
Pancreas62.15
PancreaticIslet91.45
ParietalLobe69.35
Pituitary77.7
Placenta79.4
Pons48.95
PrefrontalCortex112.85
Prostate106.85
Salivarygland38.6
SkeletalMuscle84.75
Skin46.05
SmoothMuscle80.55
Spinalcord76.75
SubthalamicNucleus65.9
SuperiorCervicalGanglion54.05
TemporalLobe65.65
Testis158.1
TestisGermCell153.6
TestisIntersitial117.25
TestisLeydigCell83.9
TestisSeminiferousTubule80.7
Thalamus91.3
Thymus90.6
Thyroid144.4
Tongue49.85
Tonsil65.95
Trachea58.3
TrigeminalGanglion47.55
Uterus133.75
UterusCorpus43.4
WholeBlood56.9
Wholebrain88.8
colon59.75
pineal_day184.8
pineal_night157.48
retina89.175
small_intestine47.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P32223
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.47 ± 0.32
Basal Forebrain7.45 ± 0.15
Basal Part of Pons7.83 ± 0.2
Cerebellar Cortex7.61 ± 0.25
Cerebellar Nuclei7.63 ± 0.34
Claustrum7.6 ± 0.2
Epithalamus7.33 ± 0.26
Frontal Lobe7.48 ± 0.26
Globus Pallidus7.51 ± 0.19
Hypothalamus7.42 ± 0.27
Insula7.45 ± 0.3
Limbic Lobe7.39 ± 0.28
Mesencephalon7.41 ± 0.23
Myelencephalon7.45 ± 0.29
Occipital Lobe7.34 ± 0.23
Parietal Lobe7.48 ± 0.24
Pontine Tegmentum7.37 ± 0.19
Striatum7.33 ± 0.24
Subthalamus7.52 ± 0.09
Temporal Lobe7.54 ± 0.24
Thalamus7.52 ± 0.19
White Matter7.5 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ciz1CBCerebellum100
100
Ciz1CTXCerebral cortex100
100
Ciz1HIPHippocampal region87.84
100
Ciz1HPFHippocampal formation99.94
100
Ciz1HYHypothalamus100
96.28
Ciz1LSXLateral septal complex72.02
55.79
Ciz1MBMidbrain76.4
77.78
Ciz1MYMedulla85.31
100
Ciz1OLFOlfactory bulb100
100
Ciz1PPons78.91
97.23
Ciz1PALPallidum93.26
91.07
Ciz1RHPRetrohippocampal region100
100
Ciz1sAMYStriatum-like amygdalar nuclei100
100
Ciz1STRStriatum99.34
82.53
Ciz1STRdStriatum dorsal region86.92
69.25
Ciz1STRvStriatum ventral region100
100
Ciz1THThalamus92.02
87.45
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009325 21 600 620 ASCSSQQEFQDHMSEPQHQQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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