AutismKB 2.0

Annotation Detail for ARIH1


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Basic Information Top
Gene Symbol:ARIH1 ( ARI,DKFZp686O13120,FLJ20329,FLJ93118,HARI,HHARI,UBCH7BP )
Gene Full Name: ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
Band: 15q24.1
Quick LinksEntrez ID:25820; OMIM: 605624; Uniprot ID:ARI1_HUMAN; ENSEMBL ID: ENSG00000166233; HGNC ID: 689
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst5 / 6231980
fetus61 / 564012108
neonate1 / 3109732
infant0 / 236200 
juvenile3 / 5555653
adult140 / 193912172
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma2 / 17475114
breast (mammary gland) tumor1 / 9417810
cervical tumor6 / 34366174
chondrosarcoma10 / 82823120
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor33 / 263845125
glioma3 / 10688328
head and neck tumor8 / 13630258
kidney tumor4 / 6895958
leukemia9 / 9584293
liver tumor5 / 9635951
lung tumor3 / 10312729
lymphoma3 / 7175541
non-neoplasia2 / 9725020
normal243 / 336030772
ovarian tumor8 / 76682104
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer2 / 10268019
retinoblastoma3 / 4635664
skin tumor6 / 12494948
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder4 / 29757134
blood10 / 12347880
bone10 / 71655139
bone marrow5 / 48801102
brain33 / 110098929
cervix11 / 48171228
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye17 / 21105480
heart10 / 89626111
intestine7 / 23447229
kidney14 / 21177766
larynx3 / 24145124
liver10 / 20774348
lung30 / 33697489
lymph1 / 4427022
lymph node12 / 91610130
mammary gland10 / 15327165
mouth6 / 6705289
muscle6 / 10771555
nerve2 / 15768126
ovary7 / 10205168
pancreas16 / 21481274
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta15 / 28082553
prostate10 / 18934552
salivary gland0 / 201550 
skin19 / 21057490
spleen0 / 539520 
stomach2 / 9661920
testis36 / 330442108
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord1 / 1368073
uterus19 / 23287881
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201878_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.45
Adipocyte5.75
AdrenalCortex8
Adrenalgland5.45
Amygdala10.3
Appendix6.75
AtrioventricularNode6.25
BDCA4+_DentriticCells10.55
Bonemarrow6.35
BronchialEpithelialCells6.85
CD105+_Endothelial6.8
CD14+_Monocytes9.5
CD19+_BCells(neg._sel.)6.55
CD33+_Myeloid24.65
CD34+20.25
CD4+_Tcells12.65
CD56+_NKCells8.3
CD71+_EarlyErythroid5.9
CD8+_Tcells12.65
CardiacMyocytes11.2
Caudatenucleus5.65
Cerebellum5.55
CerebellumPeduncles7.85
CiliaryGanglion5.2
CingulateCortex8.6
Colorectaladenocarcinoma6.35
DorsalRootGanglion5.85
FetalThyroid6.1
Fetalbrain10.05
Fetalliver5.45
Fetallung5.3
GlobusPallidus6
Heart8.5
Hypothalamus7.85
Kidney5.05
Leukemia_chronicMyelogenousK-5626.85
Leukemia_promyelocytic-HL-605.65
Leukemialymphoblastic(MOLT-4)6.35
Liver9.9
Lung6.2
Lymphnode4.85
Lymphoma_burkitts(Daudi)8.3
Lymphoma_burkitts(Raji)9.3
MedullaOblongata10.5
OccipitalLobe6.25
OlfactoryBulb4.95
Ovary4.5
Pancreas5.45
PancreaticIslet8
ParietalLobe9.65
Pituitary8.15
Placenta7.55
Pons5.9
PrefrontalCortex15.05
Prostate7.25
Salivarygland5.25
SkeletalMuscle9.75
Skin5
SmoothMuscle7.55
Spinalcord7.6
SubthalamicNucleus5.9
SuperiorCervicalGanglion7.6
TemporalLobe5.8
Testis8.75
TestisGermCell9.5
TestisIntersitial12.5
TestisLeydigCell6.7
TestisSeminiferousTubule8.05
Thalamus10.95
Thymus4.65
Thyroid8.05
Tongue6.25
Tonsil6.45
Trachea4.8
TrigeminalGanglion6.7
Uterus8.6
UterusCorpus5.65
WholeBlood7.7
Wholebrain12.75
colon6.95
pineal_day27.46
pineal_night34.62
retina7.725
small_intestine5.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P205855
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.46 ± 0.45
Basal Forebrain5.35 ± 0.42
Basal Part of Pons5.75 ± 0.34
Cerebellar Cortex5.84 ± 0.19
Cerebellar Nuclei5.57 ± 0.57
Claustrum5.39 ± 0.43
Epithalamus5.82 ± 0.36
Frontal Lobe5.59 ± 0.39
Globus Pallidus4.99 ± 0.31
Hypothalamus5.61 ± 0.16
Insula5.6 ± 0.24
Limbic Lobe5.42 ± 0.46
Mesencephalon5.57 ± 0.45
Myelencephalon5.49 ± 0.41
Occipital Lobe5.52 ± 0.39
Parietal Lobe5.64 ± 0.37
Pontine Tegmentum5.49 ± 0.43
Striatum5.31 ± 0.39
Subthalamus5.7 ± 0.16
Temporal Lobe5.53 ± 0.4
Thalamus5.45 ± 0.37
White Matter5.21 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Arih1CBCerebellum57.55
100
Arih1CTXCerebral cortex100
100
Arih1HIPHippocampal region100
100
Arih1HPFHippocampal formation100
100
Arih1HYHypothalamus66.29
62.12
Arih1LSXLateral septal complex98.67
89.79
Arih1MBMidbrain82.71
90.38
Arih1MYMedulla60.59
86.24
Arih1OLFOlfactory bulb100
100
Arih1PPons59.54
79.66
Arih1PALPallidum73.03
77.73
Arih1RHPRetrohippocampal region100
100
Arih1sAMYStriatum-like amygdalar nuclei85.83
72.19
Arih1STRStriatum100
92.63
Arih1STRdStriatum dorsal region100
95.19
Arih1STRvStriatum ventral region100
96.85
Arih1THThalamus99.29
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00026451 13 157 169 LFAECHVINPSKK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018