AutismKB 2.0

Annotation Detail for MTO1


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Basic Information Top
Gene Symbol:MTO1 ( - )
Gene Full Name: mitochondrial translation optimization 1 homolog (S. cerevisiae)
Band: 6q13
Quick LinksEntrez ID:25821; OMIM: NA; Uniprot ID:MTO1_HUMAN; ENSEMBL ID: ENSG00000135297; HGNC ID: 19261
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus26 / 56401246
neonate6 / 31097192
infant2 / 2362084
juvenile2 / 5555635
adult209 / 1939121107
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor94 / 94178998
cervical tumor2 / 3436658
chondrosarcoma4 / 8282348
colorectal tumor20 / 114246175
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor10 / 26384537
glioma5 / 10688346
head and neck tumor14 / 136302102
kidney tumor3 / 6895943
leukemia8 / 9584283
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma8 / 71755111
non-neoplasia4 / 9725041
normal172 / 336030751
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor28 / 125191223
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites3 / 4001574
bladder1 / 2975733
blood7 / 12347856
bone3 / 7165541
bone marrow3 / 4880161
brain55 / 110098949
cervix5 / 48171103
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye6 / 21105428
heart4 / 8962644
intestine30 / 234472127
kidney19 / 21177789
larynx0 / 241450 
liver5 / 20774324
lung6 / 33697417
lymph8 / 44270180
lymph node5 / 9161054
mammary gland94 / 153271613
mouth2 / 6705229
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta6 / 28082521
prostate10 / 18934552
salivary gland0 / 201550 
skin14 / 21057466
spleen14 / 53952259
stomach6 / 9661962
testis26 / 33044278
thymus14 / 81131172
thyroid12 / 47473252
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus20 / 23287885
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218716_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts112
Adipocyte34.9
AdrenalCortex38.4
Adrenalgland29.7
Amygdala36.45
Appendix36.35
AtrioventricularNode27.35
BDCA4+_DentriticCells110.5
Bonemarrow35.9
BronchialEpithelialCells64.95
CD105+_Endothelial67.45
CD14+_Monocytes40.95
CD19+_BCells(neg._sel.)110.6
CD33+_Myeloid56.65
CD34+94.6
CD4+_Tcells140.75
CD56+_NKCells68.1
CD71+_EarlyErythroid37.6
CD8+_Tcells88.15
CardiacMyocytes45.95
Caudatenucleus30.45
Cerebellum28.4
CerebellumPeduncles40.2
CiliaryGanglion26.1
CingulateCortex35.45
Colorectaladenocarcinoma36.1
DorsalRootGanglion27.95
FetalThyroid37.7
Fetalbrain30.9
Fetalliver30.5
Fetallung27.85
GlobusPallidus25.9
Heart44
Hypothalamus40.55
Kidney29.3
Leukemia_chronicMyelogenousK-56252.45
Leukemia_promyelocytic-HL-60182.1
Leukemialymphoblastic(MOLT-4)28.05
Liver47.1
Lung36.9
Lymphnode39.7
Lymphoma_burkitts(Daudi)53.2
Lymphoma_burkitts(Raji)262.15
MedullaOblongata30
OccipitalLobe29.7
OlfactoryBulb27.85
Ovary26.65
Pancreas28.9
PancreaticIslet50.05
ParietalLobe38.55
Pituitary41.15
Placenta29.05
Pons33.85
PrefrontalCortex42.45
Prostate53.1
Salivarygland30.45
SkeletalMuscle43.6
Skin29.8
SmoothMuscle38.25
Spinalcord36.9
SubthalamicNucleus32.7
SuperiorCervicalGanglion40.45
TemporalLobe32.5
Testis62.4
TestisGermCell85.65
TestisIntersitial100.25
TestisLeydigCell60.05
TestisSeminiferousTubule42.3
Thalamus35.85
Thymus23.75
Thyroid56.1
Tongue35.45
Tonsil37.25
Trachea28.35
TrigeminalGanglion36.6
Uterus36.05
UterusCorpus32.35
WholeBlood51.95
Wholebrain27.3
colon38.45
pineal_day80.22
pineal_night83
retina41.475
small_intestine40.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P145068
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.97 ± 0.43
Basal Forebrain6.23 ± 0.39
Basal Part of Pons6.6 ± 0.42
Cerebellar Cortex6.75 ± 0.17
Cerebellar Nuclei6.79 ± 0.31
Claustrum5.95 ± 0.55
Epithalamus6.67 ± 0.21
Frontal Lobe6.52 ± 0.32
Globus Pallidus6.35 ± 0.3
Hypothalamus6.66 ± 0.32
Insula6.45 ± 0.32
Limbic Lobe6.17 ± 0.44
Mesencephalon6.25 ± 0.5
Myelencephalon6.35 ± 0.42
Occipital Lobe6.15 ± 0.44
Parietal Lobe6.43 ± 0.4
Pontine Tegmentum6.45 ± 0.3
Striatum5.95 ± 0.37
Subthalamus6.63 ± 0.17
Temporal Lobe6.45 ± 0.35
Thalamus6.42 ± 0.33
White Matter6.73 ± 0.43
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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