AutismKB 2.0

Annotation Detail for TPSG1


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Basic Information Top
Gene Symbol:TPSG1 ( PRSS31,TMT,trpA )
Gene Full Name: tryptase gamma 1
Band: 16p13.3
Quick LinksEntrez ID:25823; OMIM: 609341; Uniprot ID:TRYG1_HUMAN; ENSEMBL ID: ENSG00000116176; HGNC ID: 14134
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal3 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine10 / 23447242
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220339_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.35
Adipocyte4.65
AdrenalCortex4.85
Adrenalgland4.05
Amygdala4.95
Appendix4.75
AtrioventricularNode3.55
BDCA4+_DentriticCells5.15
Bonemarrow4.6
BronchialEpithelialCells4.7
CD105+_Endothelial4.65
CD14+_Monocytes4.9
CD19+_BCells(neg._sel.)5.05
CD33+_Myeloid5.75
CD34+5.85
CD4+_Tcells5
CD56+_NKCells5.55
CD71+_EarlyErythroid4.4
CD8+_Tcells4.35
CardiacMyocytes5.95
Caudatenucleus4.25
Cerebellum3.85
CerebellumPeduncles5.3
CiliaryGanglion3.3
CingulateCortex4.8
Colorectaladenocarcinoma4.75
DorsalRootGanglion3.5
FetalThyroid4.6
Fetalbrain4.75
Fetalliver4.05
Fetallung3.95
GlobusPallidus3.35
Heart5.95
Hypothalamus5.1
Kidney3.75
Leukemia_chronicMyelogenousK-5624.25
Leukemia_promyelocytic-HL-604.15
Leukemialymphoblastic(MOLT-4)3.8
Liver6.45
Lung5.2
Lymphnode4
Lymphoma_burkitts(Daudi)5.95
Lymphoma_burkitts(Raji)6.55
MedullaOblongata4.4
OccipitalLobe4.2
OlfactoryBulb3.7
Ovary3.1
Pancreas3.75
PancreaticIslet5.15
ParietalLobe4.95
Pituitary5.5
Placenta4.8
Pons4.45
PrefrontalCortex5.7
Prostate5.55
Salivarygland3.7
SkeletalMuscle5.65
Skin3.55
SmoothMuscle5.3
Spinalcord5
SubthalamicNucleus4.2
SuperiorCervicalGanglion5.4
TemporalLobe4.25
Testis4.05
TestisGermCell3.95
TestisIntersitial4
TestisLeydigCell4.65
TestisSeminiferousTubule4
Thalamus4.75
Thymus3.7
Thyroid5.95
Tongue4.5
Tonsil4.55
Trachea3.95
TrigeminalGanglion5.2
Uterus3.85
UterusCorpus4.4
WholeBlood5.2
Wholebrain4.05
colon5.3
pineal_day5.68
pineal_night5.54
retina5.65
small_intestine4.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_810_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.83 ± 0.63
Basal Forebrain5.76 ± 0.1
Basal Part of Pons5.49 ± 0.32
Cerebellar Cortex5.58 ± 0.49
Cerebellar Nuclei6.03 ± 0.58
Claustrum6.01 ± 0.75
Epithalamus5.39 ± 0.36
Frontal Lobe5.51 ± 0.45
Globus Pallidus5.97 ± 0.39
Hypothalamus5.43 ± 0.46
Insula5.44 ± 0.33
Limbic Lobe5.66 ± 0.53
Mesencephalon5.75 ± 0.42
Myelencephalon5.68 ± 0.51
Occipital Lobe5.85 ± 0.55
Parietal Lobe5.7 ± 0.47
Pontine Tegmentum5.64 ± 0.51
Striatum5.82 ± 0.46
Subthalamus5.83 ± 0.08
Temporal Lobe5.52 ± 0.49
Thalamus5.77 ± 0.4
White Matter6.15 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tpsg1CBCerebellum0
0
Tpsg1CTXCerebral cortex0
0
Tpsg1HIPHippocampal region0
0
Tpsg1HPFHippocampal formation0
0
Tpsg1HYHypothalamus0
0
Tpsg1LSXLateral septal complex0
0
Tpsg1MBMidbrain0
0
Tpsg1MYMedulla0
0
Tpsg1OLFOlfactory bulb0
0
Tpsg1PPons0
0
Tpsg1PALPallidum0
0
Tpsg1RHPRetrohippocampal region0
0
Tpsg1sAMYStriatum-like amygdalar nuclei0
0
Tpsg1STRStriatum0
0
Tpsg1STRdStriatum dorsal region0
0
Tpsg1STRvStriatum ventral region0
0
Tpsg1THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp01419969 8 72 79 WVLTAAHC Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018