AutismKB 2.0

Annotation Detail for MOBKL3


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Basic Information Top
Gene Symbol:MOBKL3 ( 2C4D,MGC12264,MOB1,MOB3,PREI3 )
Gene Full Name: MOB1, Mps One Binder kinase activator-like 3 (yeast)
Band: 2q33.1
Quick LinksEntrez ID:25843; OMIM: 609361; Uniprot ID:MOBL3_HUMAN; ENSEMBL ID: ENSG00000115540; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst5 / 6231980
fetus37 / 56401265
neonate2 / 3109764
infant3 / 23620127
juvenile6 / 55556107
adult81 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma2 / 17475114
breast (mammary gland) tumor5 / 9417853
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor2 / 17290115
gastrointestinal tumor5 / 11936941
germ cell tumor21 / 26384579
glioma3 / 10688328
head and neck tumor7 / 13630251
kidney tumor6 / 6895987
leukemia1 / 9584210
liver tumor5 / 9635951
lung tumor4 / 10312738
lymphoma4 / 7175555
non-neoplasia1 / 9725010
normal215 / 336030763
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer3 / 10268029
retinoblastoma3 / 4635664
skin tumor3 / 12494924
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland9 / 33197271
ascites3 / 4001574
bladder3 / 29757100
blood3 / 12347824
bone1 / 7165513
bone marrow2 / 4880140
brain94 / 110098985
cervix1 / 4817120
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue19 / 21572288
esophagus2 / 2020998
eye4 / 21105418
heart8 / 8962689
intestine11 / 23447246
kidney22 / 211777103
larynx3 / 24145124
liver7 / 20774333
lung14 / 33697441
lymph0 / 442700 
lymph node10 / 91610109
mammary gland10 / 15327165
mouth6 / 6705289
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas6 / 21481227
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta13 / 28082546
prostate8 / 18934542
salivary gland2 / 2015599
skin12 / 21057456
spleen1 / 5395218
stomach3 / 9661931
testis20 / 33044260
thymus4 / 8113149
thyroid2 / 4747342
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus8 / 23287834
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202919_at
Cell line Expression level Expression bar
721_B_lymphoblasts77.65
Adipocyte22.7
AdrenalCortex321.75
Adrenalgland113.05
Amygdala64.75
Appendix49.95
AtrioventricularNode22.4
BDCA4+_DentriticCells74.7
Bonemarrow45.9
BronchialEpithelialCells48.4
CD105+_Endothelial50.9
CD14+_Monocytes59.75
CD19+_BCells(neg._sel.)74.15
CD33+_Myeloid95.05
CD34+46.85
CD4+_Tcells62.35
CD56+_NKCells146.65
CD71+_EarlyErythroid96.1
CD8+_Tcells71.8
CardiacMyocytes50.85
Caudatenucleus45.45
Cerebellum41.6
CerebellumPeduncles66
CiliaryGanglion34.9
CingulateCortex60.45
Colorectaladenocarcinoma58.15
DorsalRootGanglion27.1
FetalThyroid24.8
Fetalbrain165.8
Fetalliver43.05
Fetallung53.75
GlobusPallidus30.4
Heart25.35
Hypothalamus114
Kidney30.8
Leukemia_chronicMyelogenousK-56254.35
Leukemia_promyelocytic-HL-6040.95
Leukemialymphoblastic(MOLT-4)37.75
Liver26.8
Lung30.25
Lymphnode33.95
Lymphoma_burkitts(Daudi)58.55
Lymphoma_burkitts(Raji)45.85
MedullaOblongata68.95
OccipitalLobe67.6
OlfactoryBulb26.1
Ovary32.4
Pancreas15.75
PancreaticIslet39.75
ParietalLobe52.1
Pituitary67.2
Placenta30.35
Pons59.85
PrefrontalCortex194.2
Prostate47.25
Salivarygland32.05
SkeletalMuscle32.85
Skin19
SmoothMuscle31.9
Spinalcord51.7
SubthalamicNucleus73.3
SuperiorCervicalGanglion44.55
TemporalLobe67.6
Testis22.9
TestisGermCell28.75
TestisIntersitial12.85
TestisLeydigCell13.7
TestisSeminiferousTubule21.6
Thalamus90.9
Thymus15.65
Thyroid64.25
Tongue57.45
Tonsil65.6
Trachea42.4
TrigeminalGanglion29.25
Uterus42.15
UterusCorpus54.3
WholeBlood69.3
Wholebrain144.45
colon50.95
pineal_day113.4
pineal_night136.46
retina54.625
small_intestine49.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P210274
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.93 ± 0.33
Basal Forebrain7.79 ± 0.33
Basal Part of Pons8.04 ± 0.19
Cerebellar Cortex8.07 ± 0.2
Cerebellar Nuclei7.95 ± 0.35
Claustrum7.57 ± 0.53
Epithalamus7.92 ± 0.22
Frontal Lobe8.07 ± 0.3
Globus Pallidus7.3 ± 0.2
Hypothalamus8.04 ± 0.2
Insula8 ± 0.36
Limbic Lobe7.88 ± 0.48
Mesencephalon7.79 ± 0.47
Myelencephalon7.84 ± 0.41
Occipital Lobe7.78 ± 0.42
Parietal Lobe7.95 ± 0.4
Pontine Tegmentum7.94 ± 0.35
Striatum7.4 ± 0.35
Subthalamus8.13 ± 0.23
Temporal Lobe7.97 ± 0.29
Thalamus7.95 ± 0.3
White Matter7.21 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Prei3CBCerebellum25.55
42.62
Prei3CTXCerebral cortex24.54
19.35
Prei3HIPHippocampal region26.75
29.09
Prei3HPFHippocampal formation30.81
29.41
Prei3HYHypothalamus3.22
2.72
Prei3LSXLateral septal complex6.24
4.97
Prei3MBMidbrain8.63
9.2
Prei3MYMedulla21.77
25.64
Prei3OLFOlfactory bulb18.21
13.91
Prei3PPons15.54
18.37
Prei3PALPallidum10.54
11.23
Prei3RHPRetrohippocampal region38.33
30.57
Prei3sAMYStriatum-like amygdalar nuclei4.64
3.57
Prei3STRStriatum5.93
5.14
Prei3STRdStriatum dorsal region6.61
6.12
Prei3STRvStriatum ventral region4.03
2.82
Prei3THThalamus9.28
8.34
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MOBL3_HUMAN_2 10 2 11 VMAEGTAVLR PRIDE
PAp00003573 19 95 113 HTLDGAACLLNSNKYFPSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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