AutismKB 2.0

Annotation Detail for ZNF345


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Basic Information Top
Gene Symbol:ZNF345 ( HZF10 )
Gene Full Name: zinc finger protein 345
Band: 19q13.12
Quick LinksEntrez ID:25850; OMIM: NA; Uniprot ID:ZN345_HUMAN; ENSEMBL ID: ENSG00000167637,ENSG00000251247; HGNC ID: 16367
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult21 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal36 / 336030710
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine1 / 2344724
kidney2 / 2117779
larynx0 / 241450 
liver2 / 2077439
lung6 / 33697417
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis13 / 33044239
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207236_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.35
Adipocyte6
AdrenalCortex7.4
Adrenalgland5.35
Amygdala5.75
Appendix8.05
AtrioventricularNode4.95
BDCA4+_DentriticCells6.8
Bonemarrow6.25
BronchialEpithelialCells6
CD105+_Endothelial6.05
CD14+_Monocytes6.65
CD19+_BCells(neg._sel.)6.45
CD33+_Myeloid7.8
CD34+7.85
CD4+_Tcells6.8
CD56+_NKCells7.4
CD71+_EarlyErythroid5.85
CD8+_Tcells6
CardiacMyocytes8.75
Caudatenucleus5.5
Cerebellum4.95
CerebellumPeduncles7.2
CiliaryGanglion5.65
CingulateCortex6.55
Colorectaladenocarcinoma6.15
DorsalRootGanglion5.05
FetalThyroid6.1
Fetalbrain6.05
Fetalliver5.35
Fetallung4.95
GlobusPallidus4.7
Heart8.5
Hypothalamus6.5
Kidney5.45
Leukemia_chronicMyelogenousK-5625.5
Leukemia_promyelocytic-HL-605.45
Leukemialymphoblastic(MOLT-4)4.95
Liver8.6
Lung6.6
Lymphnode5.25
Lymphoma_burkitts(Daudi)8.3
Lymphoma_burkitts(Raji)9.4
MedullaOblongata5.6
OccipitalLobe5.5
OlfactoryBulb4.85
Ovary4.3
Pancreas5
PancreaticIslet6.55
ParietalLobe6.65
Pituitary7.2
Placenta6
Pons6
PrefrontalCortex7.55
Prostate7.1
Salivarygland5
SkeletalMuscle9.15
Skin6.9
SmoothMuscle6.8
Spinalcord6.4
SubthalamicNucleus6.05
SuperiorCervicalGanglion11.25
TemporalLobe5.85
Testis5.2
TestisGermCell5.05
TestisIntersitial5.4
TestisLeydigCell6.2
TestisSeminiferousTubule5.3
Thalamus6.3
Thymus4.4
Thyroid7.4
Tongue6.3
Tonsil6.15
Trachea4.95
TrigeminalGanglion9.25
Uterus4.95
UterusCorpus5.9
WholeBlood6.7
Wholebrain4.8
colon6.15
pineal_day7.4
pineal_night7.5
retina7.225
small_intestine5.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_735_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.13 ± 0.97
Basal Forebrain3.24 ± 1.05
Basal Part of Pons2.2 ± 0.32
Cerebellar Cortex2.8 ± 0.62
Cerebellar Nuclei2.97 ± 0.74
Claustrum3.09 ± 0.73
Epithalamus2.54 ± 0.73
Frontal Lobe2.54 ± 0.75
Globus Pallidus3.9 ± 0.55
Hypothalamus2.47 ± 0.8
Insula2.48 ± 0.48
Limbic Lobe2.81 ± 0.92
Mesencephalon2.94 ± 0.73
Myelencephalon2.87 ± 0.77
Occipital Lobe2.93 ± 0.81
Parietal Lobe2.69 ± 0.72
Pontine Tegmentum2.8 ± 0.73
Striatum2.87 ± 0.85
Subthalamus2.8 ± 0.44
Temporal Lobe2.64 ± 0.81
Thalamus2.71 ± 0.59
White Matter4.53 ± 0.42
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018