AutismKB 2.0

Annotation Detail for TRIM58


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Basic Information Top
Gene Symbol:TRIM58 ( BIA2,DKFZp434C091 )
Gene Full Name: tripartite motif-containing 58
Band: 1q44
Quick LinksEntrez ID:25893; OMIM: NA; Uniprot ID:TRI58_HUMAN; ENSEMBL ID: ENSG00000162722; HGNC ID: 24150
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult12 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal35 / 336030710
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor5 / 12494940
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow2 / 4880140
brain1 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart2 / 8962622
intestine0 / 2344720 
kidney2 / 2117779
larynx1 / 2414541
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate1 / 1893455
salivary gland2 / 2015599
skin5 / 21057423
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215047_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.7
Adipocyte8.15
AdrenalCortex11.7
Adrenalgland7.55
Amygdala7.85
Appendix14.15
AtrioventricularNode14.65
BDCA4+_DentriticCells7.8
Bonemarrow476.4
BronchialEpithelialCells7.65
CD105+_Endothelial15.75
CD14+_Monocytes9
CD19+_BCells(neg._sel.)8.7
CD33+_Myeloid10.35
CD34+19.75
CD4+_Tcells8
CD56+_NKCells9.6
CD71+_EarlyErythroid1003.7
CD8+_Tcells7.05
CardiacMyocytes12.65
Caudatenucleus7.55
Cerebellum6.85
CerebellumPeduncles10.4
CiliaryGanglion14.55
CingulateCortex8.85
Colorectaladenocarcinoma8.15
DorsalRootGanglion11.65
FetalThyroid8.5
Fetalbrain8.15
Fetalliver432.95
Fetallung6.2
GlobusPallidus7.05
Heart12.7
Hypothalamus8.5
Kidney7.95
Leukemia_chronicMyelogenousK-5627.55
Leukemia_promyelocytic-HL-607.15
Leukemialymphoblastic(MOLT-4)6.2
Liver13.9
Lung9
Lymphnode6.5
Lymphoma_burkitts(Daudi)11.7
Lymphoma_burkitts(Raji)12.7
MedullaOblongata7.5
OccipitalLobe7.25
OlfactoryBulb6.45
Ovary6.55
Pancreas7.5
PancreaticIslet9.2
ParietalLobe10.25
Pituitary9.4
Placenta18.2
Pons9
PrefrontalCortex9.8
Prostate9.3
Salivarygland7.1
SkeletalMuscle14
Skin11.3
SmoothMuscle9.4
Spinalcord8.6
SubthalamicNucleus8.85
SuperiorCervicalGanglion25.75
TemporalLobe8
Testis7.1
TestisGermCell6.5
TestisIntersitial7.45
TestisLeydigCell8.95
TestisSeminiferousTubule7.2
Thalamus8.65
Thymus5.95
Thyroid12
Tongue9.9
Tonsil8.25
Trachea6.85
TrigeminalGanglion11.3
Uterus6.2
UterusCorpus9.3
WholeBlood9.15
Wholebrain6.25
colon8.35
pineal_day9.84
pineal_night9.72
retina10.075
small_intestine7.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_221_PI417507815
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.64 ± 0.8
Basal Forebrain3.39 ± 0.48
Basal Part of Pons4.44 ± 0.28
Cerebellar Cortex3.23 ± 0.73
Cerebellar Nuclei4.18 ± 0.72
Claustrum3.66 ± 0.64
Epithalamus3.51 ± 0.66
Frontal Lobe3.87 ± 0.73
Globus Pallidus3.4 ± 0.99
Hypothalamus4.78 ± 0.8
Insula3.36 ± 0.71
Limbic Lobe3.55 ± 0.63
Mesencephalon4.05 ± 0.71
Myelencephalon3.75 ± 0.84
Occipital Lobe4.2 ± 0.53
Parietal Lobe3.81 ± 0.81
Pontine Tegmentum3.7 ± 0.7
Striatum3.35 ± 0.95
Subthalamus4.12 ± 0.32
Temporal Lobe3.8 ± 0.64
Thalamus3.45 ± 0.72
White Matter2.82 ± 0.53
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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