AutismKB 2.0

Annotation Detail for INTS7


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Basic Information Top
Gene Symbol:INTS7 ( C1orf73,DKFZp434B168,INT7 )
Gene Full Name: integrator complex subunit 7
Band: 1q32.3
Quick LinksEntrez ID:25896; OMIM: 611350; Uniprot ID:INT7_HUMAN; ENSEMBL ID: ENSG00000143493; HGNC ID: 24484
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst1 / 6231916
fetus63 / 564012111
neonate3 / 3109796
infant1 / 2362042
juvenile1 / 5555617
adult85 / 193912143
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor18 / 94178191
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor4 / 17290231
gastrointestinal tumor5 / 11936941
germ cell tumor38 / 263845144
glioma1 / 1068839
head and neck tumor18 / 136302132
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor7 / 10312767
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal173 / 336030751
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor5 / 12494940
soft tissue/muscle tissue tumor13 / 125191103
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites4 / 4001599
bladder3 / 29757100
blood7 / 12347856
bone0 / 716550 
bone marrow1 / 4880120
brain73 / 110098966
cervix4 / 4817183
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus4 / 20209197
eye2 / 2110549
heart6 / 8962666
intestine4 / 23447217
kidney6 / 21177728
larynx1 / 2414541
liver3 / 20774314
lung15 / 33697444
lymph0 / 442700 
lymph node10 / 91610109
mammary gland18 / 153271117
mouth20 / 67052298
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta6 / 28082521
prostate4 / 18934521
salivary gland0 / 201550 
skin10 / 21057447
spleen1 / 5395218
stomach1 / 9661910
testis106 / 330442320
thymus18 / 81131221
thyroid1 / 4747321
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus10 / 23287842
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 222250_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts37
Adipocyte7.45
AdrenalCortex10.15
Adrenalgland6.95
Amygdala7.8
Appendix11.2
AtrioventricularNode7.15
BDCA4+_DentriticCells7.6
Bonemarrow7.9
BronchialEpithelialCells7.3
CD105+_Endothelial10.85
CD14+_Monocytes8.25
CD19+_BCells(neg._sel.)7.4
CD33+_Myeloid9.15
CD34+13.85
CD4+_Tcells7.6
CD56+_NKCells8.55
CD71+_EarlyErythroid13.45
CD8+_Tcells6.7
CardiacMyocytes11.25
Caudatenucleus6.9
Cerebellum6.25
CerebellumPeduncles10.1
CiliaryGanglion6.35
CingulateCortex8.25
Colorectaladenocarcinoma7.7
DorsalRootGanglion6.5
FetalThyroid7.75
Fetalbrain7.5
Fetalliver7.7
Fetallung5.65
GlobusPallidus6.1
Heart10.25
Hypothalamus7.65
Kidney6.9
Leukemia_chronicMyelogenousK-5628.55
Leukemia_promyelocytic-HL-606.85
Leukemialymphoblastic(MOLT-4)15.65
Liver11.4
Lung7.85
Lymphnode6.35
Lymphoma_burkitts(Daudi)22.25
Lymphoma_burkitts(Raji)10.95
MedullaOblongata6.95
OccipitalLobe6.75
OlfactoryBulb5.95
Ovary5.6
Pancreas6.25
PancreaticIslet8.4
ParietalLobe9
Pituitary9.45
Placenta7.45
Pons7.8
PrefrontalCortex8.85
Prostate8.75
Salivarygland6.35
SkeletalMuscle22.25
Skin6.65
SmoothMuscle9.25
Spinalcord8.05
SubthalamicNucleus7.4
SuperiorCervicalGanglion12.3
TemporalLobe7.45
Testis12.7
TestisGermCell26.95
TestisIntersitial24.55
TestisLeydigCell12.25
TestisSeminiferousTubule10.05
Thalamus7.9
Thymus6.35
Thyroid9.3
Tongue8.3
Tonsil7.95
Trachea6.4
TrigeminalGanglion10.25
Uterus5.9
UterusCorpus12.8
WholeBlood8.4
Wholebrain5.85
colon7.6
pineal_day9.32
pineal_night9.02
retina8.625
small_intestine6.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7370_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.93 ± 0.4
Basal Forebrain5.96 ± 0.23
Basal Part of Pons5.92 ± 0.29
Cerebellar Cortex5.71 ± 0.33
Cerebellar Nuclei6.02 ± 0.36
Claustrum5.96 ± 0.52
Epithalamus5.64 ± 0.44
Frontal Lobe5.84 ± 0.35
Globus Pallidus5.93 ± 0.44
Hypothalamus5.78 ± 0.39
Insula5.77 ± 0.44
Limbic Lobe5.76 ± 0.3
Mesencephalon5.82 ± 0.4
Myelencephalon5.81 ± 0.37
Occipital Lobe5.71 ± 0.36
Parietal Lobe5.79 ± 0.28
Pontine Tegmentum5.77 ± 0.35
Striatum6.15 ± 0.25
Subthalamus6.05 ± 0.12
Temporal Lobe5.78 ± 0.28
Thalamus5.84 ± 0.33
White Matter6.49 ± 0.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ints7CBCerebellum22.14
28.03
Ints7CTXCerebral cortex100
81.74
Ints7HIPHippocampal region40.41
39.84
Ints7HPFHippocampal formation46.73
41.83
Ints7HYHypothalamus7.99
6.3
Ints7LSXLateral septal complex10.91
9.05
Ints7MBMidbrain8.1
7.48
Ints7MYMedulla15.99
17.53
Ints7OLFOlfactory bulb73.4
60.73
Ints7PPons13.83
16.8
Ints7PALPallidum7.64
6.33
Ints7RHPRetrohippocampal region60.43
46.81
Ints7sAMYStriatum-like amygdalar nuclei35.86
26.44
Ints7STRStriatum45.51
31.68
Ints7STRdStriatum dorsal region53.08
35.84
Ints7STRvStriatum ventral region51.69
36.94
Ints7THThalamus4.64
3.83
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
INT7_HUMAN_2 33 2 34 ASNSTKSFLADAGYGEQELDANSALMELDKGLR PRIDE
PAp00069931 15 326 340 HYFSIVPGNVSSSPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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