AutismKB 2.0

Annotation Detail for OLFML2B


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Basic Information Top
Gene Symbol:OLFML2B ( MGC51337,RP11-227F8.1 )
Gene Full Name: olfactomedin-like 2B
Band: 1q23.3
Quick LinksEntrez ID:25903; OMIM: NA; Uniprot ID:OLM2B_HUMAN; ENSEMBL ID: ENSG00000162745; HGNC ID: 24558
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus16 / 56401228
neonate4 / 31097128
infant0 / 236200 
juvenile1 / 5555617
adult59 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma5 / 10688346
head and neck tumor10 / 13630273
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia11 / 97250113
normal58 / 336030717
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor17 / 125191135
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood3 / 12347824
bone4 / 7165555
bone marrow0 / 488010 
brain20 / 110098918
cervix0 / 481710 
connective tissue13 / 14925587
ear2 / 16212123
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart6 / 8962666
intestine6 / 23447225
kidney1 / 2117774
larynx1 / 2414541
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth6 / 6705289
muscle0 / 1077150 
nerve1 / 1576863
ovary2 / 10205119
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta11 / 28082539
prostate2 / 18934510
salivary gland2 / 2015599
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis5 / 33044215
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213125_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.1
Adipocyte8.5
AdrenalCortex9.05
Adrenalgland6.8
Amygdala8.35
Appendix8.1
AtrioventricularNode6.95
BDCA4+_DentriticCells8.75
Bonemarrow7.95
BronchialEpithelialCells7.85
CD105+_Endothelial8.95
CD14+_Monocytes8.65
CD19+_BCells(neg._sel.)8.6
CD33+_Myeloid10.35
CD34+10.35
CD4+_Tcells8.8
CD56+_NKCells9.05
CD71+_EarlyErythroid7.55
CD8+_Tcells7.8
CardiacMyocytes10.25
Caudatenucleus7.2
Cerebellum6.45
CerebellumPeduncles9.1
CiliaryGanglion5.8
CingulateCortex8.25
Colorectaladenocarcinoma8
DorsalRootGanglion8.75
FetalThyroid58.5
Fetalbrain8.1
Fetalliver6.95
Fetallung9.6
GlobusPallidus5.9
Heart10.25
Hypothalamus8.8
Kidney6.5
Leukemia_chronicMyelogenousK-5627.25
Leukemia_promyelocytic-HL-606.95
Leukemialymphoblastic(MOLT-4)6.4
Liver10.55
Lung9.05
Lymphnode8.75
Lymphoma_burkitts(Daudi)9.65
Lymphoma_burkitts(Raji)11.2
MedullaOblongata7.4
OccipitalLobe7.25
OlfactoryBulb42.65
Ovary5.3
Pancreas6.45
PancreaticIslet8.55
ParietalLobe8.45
Pituitary9.4
Placenta93.55
Pons7.65
PrefrontalCortex10.05
Prostate9.3
Salivarygland6.45
SkeletalMuscle9.45
Skin6.2
SmoothMuscle8.15
Spinalcord8.6
SubthalamicNucleus7.7
SuperiorCervicalGanglion14.4
TemporalLobe8.45
Testis14.6
TestisGermCell63.45
TestisIntersitial51.35
TestisLeydigCell12.5
TestisSeminiferousTubule18.8
Thalamus8.2
Thymus6.7
Thyroid16.35
Tongue8.15
Tonsil14.8
Trachea6.75
TrigeminalGanglion8.05
Uterus14.6
UterusCorpus10.35
WholeBlood8.8
Wholebrain6.8
colon8.15
pineal_day10.58
pineal_night9.9
retina55.225
small_intestine7.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P137689
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.23 ± 0.77
Basal Forebrain5.13 ± 0.27
Basal Part of Pons5.37 ± 0.49
Cerebellar Cortex5.02 ± 0.61
Cerebellar Nuclei5.23 ± 0.35
Claustrum6.47 ± 0.59
Epithalamus4.17 ± 0.42
Frontal Lobe5.46 ± 0.62
Globus Pallidus5.09 ± 0.42
Hypothalamus5.17 ± 0.32
Insula5.55 ± 0.57
Limbic Lobe5.6 ± 0.65
Mesencephalon5.26 ± 0.53
Myelencephalon5.39 ± 0.64
Occipital Lobe5.18 ± 0.61
Parietal Lobe5.33 ± 0.57
Pontine Tegmentum5.22 ± 0.57
Striatum4.69 ± 0.86
Subthalamus5.36 ± 0.17
Temporal Lobe5.45 ± 0.49
Thalamus5.33 ± 0.48
White Matter4.88 ± 0.72
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Olfml2bCBCerebellum61.45
53.13
Olfml2bCTXCerebral cortex69.1
62.17
Olfml2bHIPHippocampal region88.63
100
Olfml2bHPFHippocampal formation84.73
89.72
Olfml2bHYHypothalamus68.73
61.66
Olfml2bLSXLateral septal complex52.06
40.85
Olfml2bMBMidbrain58.7
56.89
Olfml2bMYMedulla74.18
71.68
Olfml2bOLFOlfactory bulb71.83
63.47
Olfml2bPPons70.47
68.15
Olfml2bPALPallidum61.61
52.17
Olfml2bRHPRetrohippocampal region76.36
66.13
Olfml2bsAMYStriatum-like amygdalar nuclei65.49
51.9
Olfml2bSTRStriatum58.2
38.81
Olfml2bSTRdStriatum dorsal region56.97
31.76
Olfml2bSTRvStriatum ventral region61.84
51.48
Olfml2bTHThalamus58.34
55.62
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018