AutismKB 2.0

Annotation Detail for THUMPD3


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Basic Information Top
Gene Symbol:THUMPD3 ( DKFZp434F091 )
Gene Full Name: THUMP domain containing 3
Band: 3p25.3
Quick LinksEntrez ID:25917; OMIM: NA; Uniprot ID:THUM3_HUMAN; ENSEMBL ID: ENSG00000134077; HGNC ID: 24493
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus35 / 56401262
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult83 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor15 / 26384556
glioma6 / 10688356
head and neck tumor8 / 13630258
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal159 / 336030747
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites4 / 4001599
bladder0 / 297570 
blood0 / 1234780 
bone5 / 7165569
bone marrow0 / 488010 
brain45 / 110098940
cervix0 / 481710 
connective tissue9 / 14925560
ear2 / 16212123
embryonic tissue8 / 21572237
esophagus1 / 2020949
eye14 / 21105466
heart2 / 8962622
intestine10 / 23447242
kidney10 / 21177747
larynx5 / 24145207
liver9 / 20774343
lung24 / 33697471
lymph0 / 442700 
lymph node7 / 9161076
mammary gland4 / 15327126
mouth2 / 6705229
muscle4 / 10771537
nerve0 / 157680 
ovary3 / 10205129
pancreas6 / 21481227
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta8 / 28082528
prostate13 / 18934568
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach3 / 9661931
testis37 / 330442111
thymus1 / 8113112
thyroid5 / 47473105
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P212213
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.84 ± 0.35
Basal Forebrain8.08 ± 0.14
Basal Part of Pons8.15 ± 0.13
Cerebellar Cortex7.93 ± 0.2
Cerebellar Nuclei8.47 ± 0.23
Claustrum7.72 ± 0.47
Epithalamus8.17 ± 0.24
Frontal Lobe8.07 ± 0.22
Globus Pallidus8.5 ± 0.21
Hypothalamus8.28 ± 0.26
Insula8.04 ± 0.25
Limbic Lobe7.78 ± 0.33
Mesencephalon7.98 ± 0.27
Myelencephalon7.99 ± 0.32
Occipital Lobe7.62 ± 0.37
Parietal Lobe8.01 ± 0.26
Pontine Tegmentum8.03 ± 0.27
Striatum7.69 ± 0.25
Subthalamus8.15 ± 0.34
Temporal Lobe8.04 ± 0.28
Thalamus8.03 ± 0.24
White Matter8.79 ± 0.22
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00079304 15 485 499 TPQAFVHPSEQDGER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018