Annotation Detail for NALCN
Basic Information Top
| Gene Symbol: | NALCN ( CanIon,FLJ23913,FLJ44659,FLJ44764,MGC74524,VGCNL1,bA430M15.1 ) |
|---|---|
| Gene Full Name: | sodium leak channel, non-selective |
| Band: | 13q32.3-q33.1 |
| Quick Links | Entrez ID:259232; OMIM: 611549; Uniprot ID:NALCN_HUMAN; ENSEMBL ID: ENSG00000102452; HGNC ID: 19082 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.525146
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 8 / 564012 | 14 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 36 / 1939121 | 18 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 1 / 17290 | 57 |  |
| gastrointestinal tumor | 1 / 119369 | 8 |  |
| germ cell tumor | 1 / 263845 | 3 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 12 / 96359 | 124 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 7 / 97250 | 71 | |
| normal | 56 / 3360307 | 16 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 5 / 104616 | 47 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 60 / 1100989 | 54 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 1 / 234472 | 4 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 12 / 207743 | 57 | |
| lung | 10 / 336974 | 29 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 8 / 214812 | 37 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 2 / 280825 | 7 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 2 / 330442 | 6 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 1 / 51780 | 19 | |
Microarray in - Probe name: CUST_14424_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.26 ± 1.15 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.78 ± 0.35 | |
| Basal Part of Pons | 1.73 ± 0.66 | |
| Cerebellar Cortex | 1.79 ± 0.73 | |
| Cerebellar Nuclei | 2.16 ± 0.74 | |
| Claustrum | 2.61 ± 1.05 | |
| Epithalamus | 1.6 ± 0.95 | |
| Frontal Lobe | 1.89 ± 0.77 | |
| Globus Pallidus | 2.04 ± 0.62 | |
| Hypothalamus | 1.74 ± 0.96 | |
| Insula | 1.91 ± 0.56 | |
| Limbic Lobe | 1.84 ± 0.65 | |
| Mesencephalon | 2.09 ± 0.83 | |
| Myelencephalon | 1.95 ± 0.7 | |
| Occipital Lobe | 1.87 ± 0.67 | |
| Parietal Lobe | 1.85 ± 0.79 | |
| Pontine Tegmentum | 1.9 ± 0.77 | |
| Striatum | 1.8 ± 0.8 | |
| Subthalamus | 1.88 ± 0.71 | |
| Temporal Lobe | 1.96 ± 0.8 | |
| Thalamus | 1.8 ± 0.73 | |
| White Matter | 1.99 ± 0.66 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Vgcnl1 | CB | Cerebellum | 5.1 | |
| 6.53 | | |||
| Vgcnl1 | CTX | Cerebral cortex | 3.75 | |
| 2.92 | | |||
| Vgcnl1 | HIP | Hippocampal region | 1.39 | |
| 1.4 | | |||
| Vgcnl1 | HPF | Hippocampal formation | 1.18 | |
| 1.23 | | |||
| Vgcnl1 | HY | Hypothalamus | 0.96 | |
| 0.7 | | |||
| Vgcnl1 | LSX | Lateral septal complex | 0.98 | |
| 2.64 | | |||
| Vgcnl1 | MB | Midbrain | 1.23 | |
| 1.59 | | |||
| Vgcnl1 | MY | Medulla | 2.47 | |
| 2.57 | | |||
| Vgcnl1 | OLF | Olfactory bulb | 6.43 | |
| 4.86 | | |||
| Vgcnl1 | P | Pons | 1.07 | |
| 1.44 | | |||
| Vgcnl1 | PAL | Pallidum | 2.92 | |
| 2.26 | | |||
| Vgcnl1 | RHP | Retrohippocampal region | 0.69 | |
| 0.86 | | |||
| Vgcnl1 | sAMY | Striatum-like amygdalar nuclei | 1.99 | |
| 1.43 | | |||
| Vgcnl1 | STR | Striatum | 3.52 | |
| 2.49 | | |||
| Vgcnl1 | STRd | Striatum dorsal region | 3.75 | |
| 2.53 | | |||
| Vgcnl1 | STRv | Striatum ventral region | 4.54 | |
| 2.87 | | |||
| Vgcnl1 | TH | Thalamus | 2.21 | |
| 1.99 | |