Annotation Detail for PTPN23
Basic Information Top
| Gene Symbol: | PTPN23 ( DKFZp564F0923,HD-PTP,HDPTP,KIAA1471,PTP-TD14 ) |
|---|---|
| Gene Full Name: | protein tyrosine phosphatase, non-receptor type 23 |
| Band: | 3p21.31 |
| Quick Links | Entrez ID:25930; OMIM: 606584; Uniprot ID:PTN23_HUMAN; ENSEMBL ID: ENSG00000076201; HGNC ID: 14406 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.25524
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 4 / 70761 | 56 |  |
| blastocyst | 4 / 62319 | 64 | |
| fetus | 18 / 564012 | 31 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 3 / 55556 | 53 | |
| adult | 83 / 1939121 | 42 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 2 / 17475 | 114 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 9 / 114246 | 78 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 14 / 263845 | 53 | |
| glioma | 12 / 106883 | 112 | |
| head and neck tumor | 5 / 136302 | 36 | |
| kidney tumor | 3 / 68959 | 43 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 9 / 96359 | 93 | |
| lung tumor | 7 / 103127 | 67 | |
| lymphoma | 5 / 71755 | 69 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 119 / 3360307 | 35 | |
| ovarian tumor | 10 / 76682 | 130 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 2 / 125680 | 15 | |
| prostate cancer | 1 / 102680 | 9 |  |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 20 / 124949 | 160 | |
| soft tissue/muscle tissue tumor | 7 / 125191 | 55 | |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 1 / 29757 | 33 | |
| blood | 3 / 123478 | 24 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 41 / 1100989 | 37 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 4 / 149255 | 26 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 8 / 215722 | 37 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 11 / 211054 | 52 | |
| heart | 1 / 89626 | 11 | |
| intestine | 17 / 234472 | 72 | |
| kidney | 9 / 211777 | 42 | |
| larynx | 3 / 24145 | 124 | |
| liver | 9 / 207743 | 43 | |
| lung | 14 / 336974 | 41 | |
| lymph | 4 / 44270 | 90 | |
| lymph node | 11 / 91610 | 120 | |
| mammary gland | 8 / 153271 | 52 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 12 / 102051 | 117 | |
| pancreas | 14 / 214812 | 65 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 10 / 280825 | 35 | |
| prostate | 4 / 189345 | 21 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 21 / 210574 | 99 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 6 / 330442 | 18 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 9 / 232878 | 38 | |
| vascular | 1 / 51780 | 19 | |
Microarray in - Probe name: A_24_P179316
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 6.27 ± 0.62 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.93 ± 0.51 | |
| Basal Part of Pons | 5.66 ± 0.41 | |
| Cerebellar Cortex | 5.66 ± 0.41 | |
| Cerebellar Nuclei | 5.97 ± 0.45 | |
| Claustrum | 6.43 ± 0.7 | |
| Epithalamus | 5.5 ± 0.51 | |
| Frontal Lobe | 5.65 ± 0.53 | |
| Globus Pallidus | 6.79 ± 0.19 | |
| Hypothalamus | 5.74 ± 0.42 | |
| Insula | 5.69 ± 0.51 | |
| Limbic Lobe | 6.21 ± 0.59 | |
| Mesencephalon | 6.02 ± 0.58 | |
| Myelencephalon | 5.97 ± 0.54 | |
| Occipital Lobe | 6.4 ± 0.64 | |
| Parietal Lobe | 5.88 ± 0.52 | |
| Pontine Tegmentum | 5.93 ± 0.49 | |
| Striatum | 6.24 ± 0.54 | |
| Subthalamus | 5.72 ± 0.58 | |
| Temporal Lobe | 5.78 ± 0.49 | |
| Thalamus | 5.86 ± 0.35 | |
| White Matter | 7.01 ± 0.65 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Ptpn23 | CB | Cerebellum | 26.3 | |
| 34.81 | | |||
| Ptpn23 | CTX | Cerebral cortex | 86.84 | |
| 68.25 | | |||
| Ptpn23 | HIP | Hippocampal region | 42.37 | |
| 56.57 | | |||
| Ptpn23 | HPF | Hippocampal formation | 52.45 | |
| 57.01 | | |||
| Ptpn23 | HY | Hypothalamus | 45.01 | |
| 36.13 | | |||
| Ptpn23 | LSX | Lateral septal complex | 27.54 | |
| 18.74 | | |||
| Ptpn23 | MB | Midbrain | 33.15 | |
| 29.23 | | |||
| Ptpn23 | MY | Medulla | 27.41 | |
| 28.76 | | |||
| Ptpn23 | OLF | Olfactory bulb | 64.04 | |
| 55.32 | | |||
| Ptpn23 | P | Pons | 35.12 | |
| 35.94 | | |||
| Ptpn23 | PAL | Pallidum | 47.16 | |
| 42.7 | | |||
| Ptpn23 | RHP | Retrohippocampal region | 72.63 | |
| 60.77 | | |||
| Ptpn23 | sAMY | Striatum-like amygdalar nuclei | 49.89 | |
| 36.69 | | |||
| Ptpn23 | STR | Striatum | 41.95 | |
| 31.53 | | |||
| Ptpn23 | STRd | Striatum dorsal region | 37.9 | |
| 29.32 | | |||
| Ptpn23 | STRv | Striatum ventral region | 55.96 | |
| 39.54 | | |||
| Ptpn23 | TH | Thalamus | 53.88 | |
| 44.59 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00025696 | 18 | 1460 | 1477 | HGVPPPCKPLASASISQK | Peptide Atlas |
| PTN23_HUMAN_1223 | 11 | 1223 | 1233 | HQDVMPYDSNR | PRIDE |
| PTN23_HUMAN_518 | 10 | 518 | 527 | AMNLHVGNLR | PRIDE |